Chromatin condensates tune nuclear mechanosensing and preserve nuclear integrity to prevent cGAS activation

Sarah D’Annunzio, Martina Di Santo, Giulia Vitali, Lucia Santomaso, Daniela Michelatti, Leonardo Morelli, Chiara Bernardis, Maulana Ariefai, Shiza Nasir, Sara Lago, Lorenzo Lunelli, Claudia Testi, Emanuele Pontecorvo, Alessandro Poli, Fabrizio A Pennacchio, Paolo Maiuri, Elodie Sanchez, David Genevieve, Lorenzo Petrolli, Thomas Tarenzi, Roberto Menichetti, Raffaello Potestio, Giancarlo Ruocco, Alessio Zippo

Open source

DOI
10.1038/s44318-026-00884-z
Published
2026-08-12
Container
The EMBO Journal
Publisher
Springer Science and Business Media LLC
Open access
unknown

Credibility signals

uncertain Score 64/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

Cite this work

BibTeX

@article{allodium:10.1038/s44318-026-00884-z,
  title = {Chromatin condensates tune nuclear mechanosensing and preserve nuclear integrity to prevent cGAS activation},
  author = {Sarah D’Annunzio and Martina Di Santo and Giulia Vitali and Lucia Santomaso and Daniela Michelatti and Leonardo Morelli and Chiara Bernardis and Maulana Ariefai and Shiza Nasir and Sara Lago and Lorenzo Lunelli and Claudia Testi and Emanuele Pontecorvo and Alessandro Poli and Fabrizio A Pennacchio and Paolo Maiuri and Elodie Sanchez and David Genevieve and Lorenzo Petrolli and Thomas Tarenzi and Roberto Menichetti and Raffaello Potestio and Giancarlo Ruocco and Alessio Zippo},
  year = {2026},
  journal = {The EMBO Journal},
  doi = {10.1038/s44318-026-00884-z},
  url = {https://doi.org/10.1038/s44318-026-00884-z}
}

RIS

TY  - JOUR
TI  - Chromatin condensates tune nuclear mechanosensing and preserve nuclear integrity to prevent cGAS activation
AU  - Sarah D’Annunzio
AU  - Martina Di Santo
AU  - Giulia Vitali
AU  - Lucia Santomaso
AU  - Daniela Michelatti
AU  - Leonardo Morelli
AU  - Chiara Bernardis
AU  - Maulana Ariefai
AU  - Shiza Nasir
AU  - Sara Lago
AU  - Lorenzo Lunelli
AU  - Claudia Testi
AU  - Emanuele Pontecorvo
AU  - Alessandro Poli
AU  - Fabrizio A Pennacchio
AU  - Paolo Maiuri
AU  - Elodie Sanchez
AU  - David Genevieve
AU  - Lorenzo Petrolli
AU  - Thomas Tarenzi
AU  - Roberto Menichetti
AU  - Raffaello Potestio
AU  - Giancarlo Ruocco
AU  - Alessio Zippo
PY  - 2026
JO  - The EMBO Journal
DO  - 10.1038/s44318-026-00884-z
UR  - https://doi.org/10.1038/s44318-026-00884-z
ER  - 

APA

D’Annunzio, S., Santo, M. D., Vitali, G., Santomaso, L., Michelatti, D., Morelli, L., Bernardis, C., Ariefai, M., Nasir, S., Lago, S., Lunelli, L., Testi, C., Pontecorvo, E., Poli, A., Pennacchio, F. A., Maiuri, P., Sanchez, E., Genevieve, D., Petrolli, L., Tarenzi, T., Menichetti, R., Potestio, R., Ruocco, G., & Zippo, A. (2026). Chromatin condensates tune nuclear mechanosensing and preserve nuclear integrity to prevent cGAS activation. The EMBO Journal. https://doi.org/10.1038/s44318-026-00884-z

Source records