IRE1 activity is prognostic in localised and metastatic prostate cancer and affects epithelial lineage states.

Doultsinos D, Tomljanovic I, Pilalis E, Abusamra SM, Alshalalfa M, Parmentier R, Ahire V, Bridges IE, Figiel S, Hester J, Leach D, Nandakumar A, Wan R, Zekri Y, Zhang J, Bevan CL, O'Neill E, Lamb AD, Macauley V, Theurillat JP, Urbanucci A, Karnes RJ, Spratt DE, Davicioni E, Quigley D, Zwart W, Le Magnen C, Chatziioannou A, Mills IG

Open source

DOI: 10.1038/s44321-026-00490-w
Published: 2026 Aug 22
Container: EMBO molecular medicine
Publisher: Not recorded
Open access: no

Credibility signals

limited evidence Score 43/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

cautionDOI registered: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
cautionDOI resolves: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredOpen access status: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1038/s44321-026-00490-w,
  title = {IRE1 activity is prognostic in localised and metastatic prostate cancer and affects epithelial lineage states.},
  author = {Doultsinos D and Tomljanovic I and Pilalis E and Abusamra SM and Alshalalfa M and Parmentier R and Ahire V and Bridges IE and Figiel S and Hester J and Leach D and Nandakumar A and Wan R and Zekri Y and Zhang J and Bevan CL and O'Neill E and Lamb AD and Macauley V and Theurillat JP and Urbanucci A and Karnes RJ and Spratt DE and Davicioni E and Quigley D and Zwart W and Le Magnen C and Chatziioannou A and Mills IG},
  year = {2026},
  journal = {EMBO molecular medicine},
  doi = {10.1038/s44321-026-00490-w},
  url = {https://doi.org/10.1038/s44321-026-00490-w}
}

RIS

TY  - JOUR
TI  - IRE1 activity is prognostic in localised and metastatic prostate cancer and affects epithelial lineage states.
AU  - Doultsinos D
AU  - Tomljanovic I
AU  - Pilalis E
AU  - Abusamra SM
AU  - Alshalalfa M
AU  - Parmentier R
AU  - Ahire V
AU  - Bridges IE
AU  - Figiel S
AU  - Hester J
AU  - Leach D
AU  - Nandakumar A
AU  - Wan R
AU  - Zekri Y
AU  - Zhang J
AU  - Bevan CL
AU  - O'Neill E
AU  - Lamb AD
AU  - Macauley V
AU  - Theurillat JP
AU  - Urbanucci A
AU  - Karnes RJ
AU  - Spratt DE
AU  - Davicioni E
AU  - Quigley D
AU  - Zwart W
AU  - Le Magnen C
AU  - Chatziioannou A
AU  - Mills IG
PY  - 2026
JO  - EMBO molecular medicine
DO  - 10.1038/s44321-026-00490-w
UR  - https://doi.org/10.1038/s44321-026-00490-w
ER  -

APA

D, D., I, T., E, P., SM, A., M, A., R, P., V, A., IE, B., S, F., J, H., D, L., A, N., R, W., Y, Z., J, Z., CL, B., E, O., AD, L., V, M., JP, T., A, U., RJ, K., DE, S., E, D., D, Q., W, Z., C, L. M., A, C., & IG, M. (2026). IRE1 activity is prognostic in localised and metastatic prostate cancer and affects epithelial lineage states.. EMBO molecular medicine. https://doi.org/10.1038/s44321-026-00490-w

Source records

pubmed · retrieved 2026-09-26T14:14:50.312Z
europe-pmc · retrieved 2026-09-26T14:14:50.306Z