Structure-activity relationships in a series of dihydrouracil-JQ1 conjugates: discovery of highly potent BRD4 degraders.

Shyshlyk O, Stadnichenko V, Diachenko O, Chernysh I, Beshtynarska A, Alieksieieva D, Khotinets D, Oleksiak O, Lesyk D, Yeremenko Y, Biitseva AV, Borysko P, Yarmolchuk V, Tolstanova GM, Grygorenko OO

Open source

DOI: 10.1039/d6md00259e
Published: 2026 May 7
Container: RSC medicinal chemistry
Publisher: Not recorded
Open access: yes

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Cite this work

BibTeX

@article{allodium:10.1039/d6md00259e,
  title = {Structure-activity relationships in a series of dihydrouracil-JQ1 conjugates: discovery of highly potent BRD4 degraders.},
  author = {Shyshlyk O and Stadnichenko V and Diachenko O and Chernysh I and Beshtynarska A and Alieksieieva D and Khotinets D and Oleksiak O and Lesyk D and Yeremenko Y and Biitseva AV and Borysko P and Yarmolchuk V and Tolstanova GM and Grygorenko OO},
  year = {2026},
  journal = {RSC medicinal chemistry},
  doi = {10.1039/d6md00259e},
  url = {https://doi.org/10.1039/d6md00259e}
}

RIS

TY  - JOUR
TI  - Structure-activity relationships in a series of dihydrouracil-JQ1 conjugates: discovery of highly potent BRD4 degraders.
AU  - Shyshlyk O
AU  - Stadnichenko V
AU  - Diachenko O
AU  - Chernysh I
AU  - Beshtynarska A
AU  - Alieksieieva D
AU  - Khotinets D
AU  - Oleksiak O
AU  - Lesyk D
AU  - Yeremenko Y
AU  - Biitseva AV
AU  - Borysko P
AU  - Yarmolchuk V
AU  - Tolstanova GM
AU  - Grygorenko OO
PY  - 2026
JO  - RSC medicinal chemistry
DO  - 10.1039/d6md00259e
UR  - https://doi.org/10.1039/d6md00259e
ER  -

APA

O, S., V, S., O, D., I, C., A, B., D, A., D, K., O, O., D, L., Y, Y., AV, B., P, B., V, Y., GM, T., & OO, G. (2026). Structure-activity relationships in a series of dihydrouracil-JQ1 conjugates: discovery of highly potent BRD4 degraders.. RSC medicinal chemistry. https://doi.org/10.1039/d6md00259e

Source records

pubmed · retrieved 2026-09-27T09:25:59.888Z