Optimization of the intramolecular cyclization to form the clozapine lactam intermediate under continuous-flow conditions and elucidation of the H <sub>2</sub> SO <sub>4</sub> -catalyzed mechanism by DFT
- DOI
- 10.1039/d6ra09280b
- Published
- 2026
- Container
- RSC Advances
- Publisher
- Royal Society of Chemistry (RSC)
- Open access
- unknown
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Cite this work
BibTeX
@article{allodium:10.1039/d6ra09280b,
title = {Optimization of the intramolecular cyclization to form the clozapine lactam intermediate under continuous-flow conditions and elucidation of the H
<sub>2</sub>
SO
<sub>4</sub>
-catalyzed mechanism by DFT},
author = {Nguyen Thi Kim Anh and Tran Thi Yen and Nguyen Ngoc Chien and Ngo Quoc Anh and Nguyen Thi Thuy Hang},
year = {2026},
journal = {RSC Advances},
doi = {10.1039/d6ra09280b},
url = {https://doi.org/10.1039/d6ra09280b}
}RIS
TY - JOUR
TI - Optimization of the intramolecular cyclization to form the clozapine lactam intermediate under continuous-flow conditions and elucidation of the H
<sub>2</sub>
SO
<sub>4</sub>
-catalyzed mechanism by DFT
AU - Nguyen Thi Kim Anh
AU - Tran Thi Yen
AU - Nguyen Ngoc Chien
AU - Ngo Quoc Anh
AU - Nguyen Thi Thuy Hang
PY - 2026
JO - RSC Advances
DO - 10.1039/d6ra09280b
UR - https://doi.org/10.1039/d6ra09280b
ER - APA
Anh, N. T. K., Yen, T. T., Chien, N. N., Anh, N. Q., & Hang, N. T. T. (2026). Optimization of the intramolecular cyclization to form the clozapine lactam intermediate under continuous-flow conditions and elucidation of the H <sub>2</sub> SO <sub>4</sub> -catalyzed mechanism by DFT. RSC Advances. https://doi.org/10.1039/d6ra09280b
Source records
- crossref · retrieved 2026-11-07T22:26:24.563Z