BIRC3 (Encoding cIAP2) Variants Result in Dysregulated RIPK1 Signaling Leading to Increased Epithelial Cell Death and Are Associated With Monogenic Crohn’s Disease

Qi Li, Ryusuke Nambu, Hu Yaqiang, Xiang Shen, Carmen Argmann, Rei Guan, Erin Janssen, Tom Le Voyer, Neil Warner, Daniel D. Yu, Jing Guo, Kelvin Long, Jodie Ouahed, Michael Field, Lauren Collen, Jonas Bibus, David Illig, Meino Rohlfs, Ziqi Yu, Shaohong Yang, Wenjuan Li, Craig D. Platt, Phillip H. Comella, Daniel Jordan, Mayte Suárez-Fariñas, Mohammed F. Alosaimi, Lauren A. Peters, Jeremie Rosain, Claire Fieschi, Anne Puel, Elena W.Y. Hsieh, Takeo Naito, Zhiyang Zeng, Marta Velasco Rodríguez-Belvís, Laura Palomino, Peter Küster, Dalin Li, Christoph Klein, Scott B. Snapper, Jean-Laurent Casanova, Raif Geha, Edward Hoffenberg, Dermot P.B. McGovern, Eric Schadt, Daniel Kotlarz, Dali Li, Aleixo M. Muise

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DOI: 10.1053/j.gastro.2026.05.022
Published: 2026-06
Container: Gastroenterology
Publisher: Elsevier BV
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1053/j.gastro.2026.05.022,
  title = {BIRC3 (Encoding cIAP2) Variants Result in Dysregulated RIPK1 Signaling Leading to Increased Epithelial Cell Death and Are Associated With Monogenic Crohn’s Disease},
  author = {Qi Li and Ryusuke Nambu and Hu Yaqiang and Xiang Shen and Carmen Argmann and Rei Guan and Erin Janssen and Tom Le Voyer and Neil Warner and Daniel D. Yu and Jing Guo and Kelvin Long and Jodie Ouahed and Michael Field and Lauren Collen and Jonas Bibus and David Illig and Meino Rohlfs and Ziqi Yu and Shaohong Yang and Wenjuan Li and Craig D. Platt and Phillip H. Comella and Daniel Jordan and Mayte Suárez-Fariñas and Mohammed F. Alosaimi and Lauren A. Peters and Jeremie Rosain and Claire Fieschi and Anne Puel and Elena W.Y. Hsieh and Takeo Naito and Zhiyang Zeng and Marta Velasco Rodríguez-Belvís and Laura Palomino and Peter Küster and Dalin Li and Christoph Klein and Scott B. Snapper and Jean-Laurent Casanova and Raif Geha and Edward Hoffenberg and Dermot P.B. McGovern and Eric Schadt and Daniel Kotlarz and Dali Li and Aleixo M. Muise},
  year = {2026},
  journal = {Gastroenterology},
  doi = {10.1053/j.gastro.2026.05.022},
  url = {https://doi.org/10.1053/j.gastro.2026.05.022}
}

RIS

TY  - JOUR
TI  - BIRC3 (Encoding cIAP2) Variants Result in Dysregulated RIPK1 Signaling Leading to Increased Epithelial Cell Death and Are Associated With Monogenic Crohn’s Disease
AU  - Qi Li
AU  - Ryusuke Nambu
AU  - Hu Yaqiang
AU  - Xiang Shen
AU  - Carmen Argmann
AU  - Rei Guan
AU  - Erin Janssen
AU  - Tom Le Voyer
AU  - Neil Warner
AU  - Daniel D. Yu
AU  - Jing Guo
AU  - Kelvin Long
AU  - Jodie Ouahed
AU  - Michael Field
AU  - Lauren Collen
AU  - Jonas Bibus
AU  - David Illig
AU  - Meino Rohlfs
AU  - Ziqi Yu
AU  - Shaohong Yang
AU  - Wenjuan Li
AU  - Craig D. Platt
AU  - Phillip H. Comella
AU  - Daniel Jordan
AU  - Mayte Suárez-Fariñas
AU  - Mohammed F. Alosaimi
AU  - Lauren A. Peters
AU  - Jeremie Rosain
AU  - Claire Fieschi
AU  - Anne Puel
AU  - Elena W.Y. Hsieh
AU  - Takeo Naito
AU  - Zhiyang Zeng
AU  - Marta Velasco Rodríguez-Belvís
AU  - Laura Palomino
AU  - Peter Küster
AU  - Dalin Li
AU  - Christoph Klein
AU  - Scott B. Snapper
AU  - Jean-Laurent Casanova
AU  - Raif Geha
AU  - Edward Hoffenberg
AU  - Dermot P.B. McGovern
AU  - Eric Schadt
AU  - Daniel Kotlarz
AU  - Dali Li
AU  - Aleixo M. Muise
PY  - 2026
JO  - Gastroenterology
DO  - 10.1053/j.gastro.2026.05.022
UR  - https://doi.org/10.1053/j.gastro.2026.05.022
ER  -

APA

Li, Q., Nambu, R., Yaqiang, H., Shen, X., Argmann, C., Guan, R., Janssen, E., Voyer, T. L., Warner, N., Yu, D. D., Guo, J., Long, K., Ouahed, J., Field, M., Collen, L., Bibus, J., Illig, D., Rohlfs, M., Yu, Z., Yang, S., Li, W., Platt, C. D., Comella, P. H., Jordan, D., Suárez-Fariñas, M., Alosaimi, M. F., Peters, L. A., Rosain, J., Fieschi, C., Puel, A., Hsieh, E. W., Naito, T., Zeng, Z., Rodríguez-Belvís, M. V., Palomino, L., Küster, P., Li, D., Klein, C., Snapper, S. B., Casanova, J., Geha, R., Hoffenberg, E., McGovern, D. P., Schadt, E., Kotlarz, D., Li, D., & Muise, A. M. (2026). BIRC3 (Encoding cIAP2) Variants Result in Dysregulated RIPK1 Signaling Leading to Increased Epithelial Cell Death and Are Associated With Monogenic Crohn’s Disease. Gastroenterology. https://doi.org/10.1053/j.gastro.2026.05.022

Source records

crossref · retrieved 2026-09-26T16:15:11.578Z