Intravenous Doxycycline, Azithromycin, or Both for Severe Scrub Typhus.

Varghese GM, Dayanand D, Gunasekaran K, Kundu D, Wyawahare M, Sharma N, Chaudhry D, Mahajan SK, Saravu K, Aruldhas BW, Mathew BS, Nair RG, Newbigging N, Mathew A, Abhilash KPP, Biswal M, Prasad AH, Zachariah A, Iyadurai R, Hansdak SG, Sathyendra S, Sudarsanam TD, Prakash JAJ, Manesh A, Mohan A, Tarning J, Blacksell SD, Peerawaranun P, Waithira N, Mukaka M, Cheah PY, Peter JV, Abraham OC, Day NPJ, INTREST Trial Investigators

Open source

DOI: 10.1056/nejmoa2208449
Published: 2023 Mar 2
Container: The New England journal of medicine
Publisher: Not recorded
Open access: yes

Credibility signals

limited evidence Score 45/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

cautionDOI registered: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
cautionDOI resolves: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
supportingOpen access status: Normalized open-access status: open. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1056/nejmoa2208449,
  title = {Intravenous Doxycycline, Azithromycin, or Both for Severe Scrub Typhus.},
  author = {Varghese GM and Dayanand D and Gunasekaran K and Kundu D and Wyawahare M and Sharma N and Chaudhry D and Mahajan SK and Saravu K and Aruldhas BW and Mathew BS and Nair RG and Newbigging N and Mathew A and Abhilash KPP and Biswal M and Prasad AH and Zachariah A and Iyadurai R and Hansdak SG and Sathyendra S and Sudarsanam TD and Prakash JAJ and Manesh A and Mohan A and Tarning J and Blacksell SD and Peerawaranun P and Waithira N and Mukaka M and Cheah PY and Peter JV and Abraham OC and Day NPJ and INTREST Trial Investigators},
  year = {2023},
  journal = {The New England journal of medicine},
  doi = {10.1056/nejmoa2208449},
  url = {https://doi.org/10.1056/nejmoa2208449}
}

RIS

TY  - JOUR
TI  - Intravenous Doxycycline, Azithromycin, or Both for Severe Scrub Typhus.
AU  - Varghese GM
AU  - Dayanand D
AU  - Gunasekaran K
AU  - Kundu D
AU  - Wyawahare M
AU  - Sharma N
AU  - Chaudhry D
AU  - Mahajan SK
AU  - Saravu K
AU  - Aruldhas BW
AU  - Mathew BS
AU  - Nair RG
AU  - Newbigging N
AU  - Mathew A
AU  - Abhilash KPP
AU  - Biswal M
AU  - Prasad AH
AU  - Zachariah A
AU  - Iyadurai R
AU  - Hansdak SG
AU  - Sathyendra S
AU  - Sudarsanam TD
AU  - Prakash JAJ
AU  - Manesh A
AU  - Mohan A
AU  - Tarning J
AU  - Blacksell SD
AU  - Peerawaranun P
AU  - Waithira N
AU  - Mukaka M
AU  - Cheah PY
AU  - Peter JV
AU  - Abraham OC
AU  - Day NPJ
AU  - INTREST Trial Investigators
PY  - 2023
JO  - The New England journal of medicine
DO  - 10.1056/nejmoa2208449
UR  - https://doi.org/10.1056/nejmoa2208449
ER  -

APA

GM, V., D, D., K, G., D, K., M, W., N, S., D, C., SK, M., K, S., BW, A., BS, M., RG, N., N, N., A, M., KPP, A., M, B., AH, P., A, Z., R, I., SG, H., S, S., TD, S., JAJ, P., A, M., A, M., J, T., SD, B., P, P., N, W., M, M., PY, C., JV, P., OC, A., NPJ, D., & Investigators, I. T. (2023). Intravenous Doxycycline, Azithromycin, or Both for Severe Scrub Typhus.. The New England journal of medicine. https://doi.org/10.1056/nejmoa2208449

Source records

pubmed · retrieved 2026-09-26T21:18:10.500Z
europe-pmc · retrieved 2026-09-26T21:18:10.517Z