Phase 3 Trial of Weekly Oral Islatravir–Lenacapavir for HIV-1 Treatment

Jürgen K. Rockstroh, Moti N. Ramgopal, Adrian Curran Fàbregas, Malcolm Hedgcock, Kimberly A. Workowski, Sylvie Ronot-Bregigeon, Isabel Cassetti, Cynthia Brinson, Samir K. Gupta, Chien-Ching Hung, Mark O’Reilly, Jihad Slim, Hiroyuki Gatanaga, Peter Shalit, Shan-Yu Liu, Stephanie O. Klopfer, Fadi Shihadeh, Nidhi Patel, Reneé-Claude Mercier, Melissa Shaughnessy, Hadas Dvory-Sobol, Devi SenGupta, Cyril Llamoso, Martin S. Rhee, Chloe Orkin

Open source

DOI: 10.1056/nejmoa2607973
Published: 2026-10-01
Container: New England Journal of Medicine
Publisher: Massachusetts Medical Society
Open access: unknown

Credibility signals

uncertain Score 64/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

supportingDOI registered: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
supportingDOI resolves: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredOpen access status: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
supportingMetadata completeness: All 6 scored descriptive metadata groups are present. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1056/nejmoa2607973,
  title = {Phase 3 Trial of Weekly Oral Islatravir–Lenacapavir for HIV-1 Treatment},
  author = {Jürgen K. Rockstroh and Moti N. Ramgopal and Adrian Curran Fàbregas and Malcolm Hedgcock and Kimberly A. Workowski and Sylvie Ronot-Bregigeon and Isabel Cassetti and Cynthia Brinson and Samir K. Gupta and Chien-Ching Hung and Mark O’Reilly and Jihad Slim and Hiroyuki Gatanaga and Peter Shalit and Shan-Yu Liu and Stephanie O. Klopfer and Fadi Shihadeh and Nidhi Patel and Reneé-Claude Mercier and Melissa Shaughnessy and Hadas Dvory-Sobol and Devi SenGupta and Cyril Llamoso and Martin S. Rhee and Chloe Orkin},
  year = {2026},
  journal = {New England Journal of Medicine},
  doi = {10.1056/nejmoa2607973},
  url = {https://doi.org/10.1056/nejmoa2607973}
}

RIS

TY  - JOUR
TI  - Phase 3 Trial of Weekly Oral Islatravir–Lenacapavir for HIV-1 Treatment
AU  - Jürgen K. Rockstroh
AU  - Moti N. Ramgopal
AU  - Adrian Curran Fàbregas
AU  - Malcolm Hedgcock
AU  - Kimberly A. Workowski
AU  - Sylvie Ronot-Bregigeon
AU  - Isabel Cassetti
AU  - Cynthia Brinson
AU  - Samir K. Gupta
AU  - Chien-Ching Hung
AU  - Mark O’Reilly
AU  - Jihad Slim
AU  - Hiroyuki Gatanaga
AU  - Peter Shalit
AU  - Shan-Yu Liu
AU  - Stephanie O. Klopfer
AU  - Fadi Shihadeh
AU  - Nidhi Patel
AU  - Reneé-Claude Mercier
AU  - Melissa Shaughnessy
AU  - Hadas Dvory-Sobol
AU  - Devi SenGupta
AU  - Cyril Llamoso
AU  - Martin S. Rhee
AU  - Chloe Orkin
PY  - 2026
JO  - New England Journal of Medicine
DO  - 10.1056/nejmoa2607973
UR  - https://doi.org/10.1056/nejmoa2607973
ER  -

APA

Rockstroh, J. K., Ramgopal, M. N., Fàbregas, A. C., Hedgcock, M., Workowski, K. A., Ronot-Bregigeon, S., Cassetti, I., Brinson, C., Gupta, S. K., Hung, C., O’Reilly, M., Slim, J., Gatanaga, H., Shalit, P., Liu, S., Klopfer, S. O., Shihadeh, F., Patel, N., Mercier, R., Shaughnessy, M., Dvory-Sobol, H., SenGupta, D., Llamoso, C., Rhee, M. S., & Orkin, C. (2026). Phase 3 Trial of Weekly Oral Islatravir–Lenacapavir for HIV-1 Treatment. New England Journal of Medicine. https://doi.org/10.1056/nejmoa2607973

Source records

crossref · retrieved 2026-11-09T13:13:13.449Z