MDFIC2 is a PIEZO channel modulator that can alleviate mechanical allodynia associated with neuropathic pain

Abdella M. Habib, Shengnan Li, Chenjing Zhang, Meijun Ji, Nancy Osorio, Virginie Penalba, Jesus M. Torres, Samuel J. Gossage, Mehdi A. Rezai, Amy F. Geard, Ahad A. Rahim, Ahmed M. M. Mahmoud, Sonia Santana-Varela, Jun Zhou, Jing Zhao, John N. Wood, Andrei L. Okorokov, Xuelong Zhou, James J. Cox, Bertrand Coste

Open source

DOI: 10.1073/pnas.2512426122
Published: 2025-11-07
Container: Proceedings of the National Academy of Sciences
Publisher: National Academy of Sciences
Open access: unknown

Credibility signals

uncertain Score 64/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

supportingDOI registered: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
supportingDOI resolves: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredOpen access status: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
supportingMetadata completeness: All 6 scored descriptive metadata groups are present. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1073/pnas.2512426122,
  title = {MDFIC2 is a PIEZO channel modulator that can alleviate mechanical allodynia associated with neuropathic pain},
  author = {Abdella M. Habib and Shengnan Li and Chenjing Zhang and Meijun Ji and Nancy Osorio and Virginie Penalba and Jesus M. Torres and Samuel J. Gossage and Mehdi A. Rezai and Amy F. Geard and Ahad A. Rahim and Ahmed M. M. Mahmoud and Sonia Santana-Varela and Jun Zhou and Jing Zhao and John N. Wood and Andrei L. Okorokov and Xuelong Zhou and James J. Cox and Bertrand Coste},
  year = {2025},
  journal = {Proceedings of the National Academy of Sciences},
  doi = {10.1073/pnas.2512426122},
  url = {https://doi.org/10.1073/pnas.2512426122}
}

RIS

TY  - JOUR
TI  - MDFIC2 is a PIEZO channel modulator that can alleviate mechanical allodynia associated with neuropathic pain
AU  - Abdella M. Habib
AU  - Shengnan Li
AU  - Chenjing Zhang
AU  - Meijun Ji
AU  - Nancy Osorio
AU  - Virginie Penalba
AU  - Jesus M. Torres
AU  - Samuel J. Gossage
AU  - Mehdi A. Rezai
AU  - Amy F. Geard
AU  - Ahad A. Rahim
AU  - Ahmed M. M. Mahmoud
AU  - Sonia Santana-Varela
AU  - Jun Zhou
AU  - Jing Zhao
AU  - John N. Wood
AU  - Andrei L. Okorokov
AU  - Xuelong Zhou
AU  - James J. Cox
AU  - Bertrand Coste
PY  - 2025
JO  - Proceedings of the National Academy of Sciences
DO  - 10.1073/pnas.2512426122
UR  - https://doi.org/10.1073/pnas.2512426122
ER  -

APA

Habib, A. M., Li, S., Zhang, C., Ji, M., Osorio, N., Penalba, V., Torres, J. M., Gossage, S. J., Rezai, M. A., Geard, A. F., Rahim, A. A., Mahmoud, A. M. M., Santana-Varela, S., Zhou, J., Zhao, J., Wood, J. N., Okorokov, A. L., Zhou, X., Cox, J. J., & Coste, B. (2025). MDFIC2 is a PIEZO channel modulator that can alleviate mechanical allodynia associated with neuropathic pain. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.2512426122

Source records

crossref · retrieved 2026-11-10T11:19:46.688Z