AI-derived therapeutic development of a serotonin receptor–targeting drug for the treatment of opioid use disorder

Valeria Lallai, Samuel Kho, A. C. Martin, James P. Fowler, Madison L. Roach, Kevin Wang, Kendyl N. Laumann, Tyler G. Morris, Mina Palaniappan, Malia Bautista, Allison S. Mogul, Jinjutha E. Cheepluesak, Bijay Shrestha, Dhanaji M. Lade, Julia E. Lagomarsino, Vaishnavi Narayan, Jayson Uffens, Waldemar Lernhardt, Saman Mirzaei, Ian Jenkins, Arturo R. Zavala, Jonathan R. T. Lakey, Robert Tinder, Christie D. Fowler

Open source

DOI: 10.1073/pnas.2516807123
Published: 2026-04-06
Container: Proceedings of the National Academy of Sciences
Publisher: National Academy of Sciences
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1073/pnas.2516807123,
  title = {AI-derived therapeutic development of a serotonin receptor–targeting drug for the treatment of opioid use disorder},
  author = {Valeria Lallai and Samuel Kho and A. C. Martin and James P. Fowler and Madison L. Roach and Kevin Wang and Kendyl N. Laumann and Tyler G. Morris and Mina Palaniappan and Malia Bautista and Allison S. Mogul and Jinjutha E. Cheepluesak and Bijay Shrestha and Dhanaji M. Lade and Julia E. Lagomarsino and Vaishnavi Narayan and Jayson Uffens and Waldemar Lernhardt and Saman Mirzaei and Ian Jenkins and Arturo R. Zavala and Jonathan R. T. Lakey and Robert Tinder and Christie D. Fowler},
  year = {2026},
  journal = {Proceedings of the National Academy of Sciences},
  doi = {10.1073/pnas.2516807123},
  url = {https://doi.org/10.1073/pnas.2516807123}
}

RIS

TY  - JOUR
TI  - AI-derived therapeutic development of a serotonin receptor–targeting drug for the treatment of opioid use disorder
AU  - Valeria Lallai
AU  - Samuel Kho
AU  - A. C. Martin
AU  - James P. Fowler
AU  - Madison L. Roach
AU  - Kevin Wang
AU  - Kendyl N. Laumann
AU  - Tyler G. Morris
AU  - Mina Palaniappan
AU  - Malia Bautista
AU  - Allison S. Mogul
AU  - Jinjutha E. Cheepluesak
AU  - Bijay Shrestha
AU  - Dhanaji M. Lade
AU  - Julia E. Lagomarsino
AU  - Vaishnavi Narayan
AU  - Jayson Uffens
AU  - Waldemar Lernhardt
AU  - Saman Mirzaei
AU  - Ian Jenkins
AU  - Arturo R. Zavala
AU  - Jonathan R. T. Lakey
AU  - Robert Tinder
AU  - Christie D. Fowler
PY  - 2026
JO  - Proceedings of the National Academy of Sciences
DO  - 10.1073/pnas.2516807123
UR  - https://doi.org/10.1073/pnas.2516807123
ER  -

APA

Lallai, V., Kho, S., Martin, A. C., Fowler, J. P., Roach, M. L., Wang, K., Laumann, K. N., Morris, T. G., Palaniappan, M., Bautista, M., Mogul, A. S., Cheepluesak, J. E., Shrestha, B., Lade, D. M., Lagomarsino, J. E., Narayan, V., Uffens, J., Lernhardt, W., Mirzaei, S., Jenkins, I., Zavala, A. R., Lakey, J. R. T., Tinder, R., & Fowler, C. D. (2026). AI-derived therapeutic development of a serotonin receptor–targeting drug for the treatment of opioid use disorder. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.2516807123

Source records

crossref · retrieved 2026-11-10T21:43:18.309Z