RNA-binding activity of PHGDH drives amyloid-beta production in a human brain organoid model of sporadic Alzheimer's disease.

Chen J, Xu M, Liu Y, Hadi F, Xue S, Chien S, Zhong S

Open source

DOI
10.1073/pnas.2532234123
Published
2026 Feb 24
Container
Proceedings of the National Academy of Sciences of the United States of America
Publisher
Not recorded
Open access
yes

Credibility signals

limited evidence Score 45/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

Cite this work

BibTeX

@article{allodium:10.1073/pnas.2532234123,
  title = {RNA-binding activity of PHGDH drives amyloid-beta production in a human brain organoid model of sporadic Alzheimer's disease.},
  author = {Chen J and Xu M and Liu Y and Hadi F and Xue S and Chien S and Zhong S},
  year = {2026},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  doi = {10.1073/pnas.2532234123},
  url = {https://doi.org/10.1073/pnas.2532234123}
}

RIS

TY  - JOUR
TI  - RNA-binding activity of PHGDH drives amyloid-beta production in a human brain organoid model of sporadic Alzheimer's disease.
AU  - Chen J
AU  - Xu M
AU  - Liu Y
AU  - Hadi F
AU  - Xue S
AU  - Chien S
AU  - Zhong S
PY  - 2026
JO  - Proceedings of the National Academy of Sciences of the United States of America
DO  - 10.1073/pnas.2532234123
UR  - https://doi.org/10.1073/pnas.2532234123
ER  - 

APA

J, C., M, X., Y, L., F, H., S, X., S, C., & S, Z. (2026). RNA-binding activity of PHGDH drives amyloid-beta production in a human brain organoid model of sporadic Alzheimer's disease.. Proceedings of the National Academy of Sciences of the United States of America. https://doi.org/10.1073/pnas.2532234123

Source records