Selectively targeting inosine monophosphate dehydrogenase-2 impairs brain metastatic potential while preserving immune cell function.

Kieliszek AM, Apel E, Zheng S, Piotrowski M, Chui D, Alazet S, Shamsi S, Mobilio D, Johnson JW, Escudero L, Vandevoorde K, Mei L, Acevedo M, Sabbatani J, Kent OA, Dordahan F, Yadav A, MacKay B, Leguay K, Berger KJ, Miletic P, Zhai K, Ang P, Huebner A, Chafe SC, Sturino C, Szychowski J, Venugopal C, Mancini J, Phinney AL, Magolan J, Singh SK

Open source

DOI
10.1073/pnas.2603440123
Published
2026 Jun 23
Container
Proceedings of the National Academy of Sciences of the United States of America
Publisher
Not recorded
Open access
yes

Credibility signals

limited evidence Score 45/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

Cite this work

BibTeX

@article{allodium:10.1073/pnas.2603440123,
  title = {Selectively targeting inosine monophosphate dehydrogenase-2 impairs brain metastatic potential while preserving immune cell function.},
  author = {Kieliszek AM and Apel E and Zheng S and Piotrowski M and Chui D and Alazet S and Shamsi S and Mobilio D and Johnson JW and Escudero L and Vandevoorde K and Mei L and Acevedo M and Sabbatani J and Kent OA and Dordahan F and Yadav A and MacKay B and Leguay K and Berger KJ and Miletic P and Zhai K and Ang P and Huebner A and Chafe SC and Sturino C and Szychowski J and Venugopal C and Mancini J and Phinney AL and Magolan J and Singh SK},
  year = {2026},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  doi = {10.1073/pnas.2603440123},
  url = {https://doi.org/10.1073/pnas.2603440123}
}

RIS

TY  - JOUR
TI  - Selectively targeting inosine monophosphate dehydrogenase-2 impairs brain metastatic potential while preserving immune cell function.
AU  - Kieliszek AM
AU  - Apel E
AU  - Zheng S
AU  - Piotrowski M
AU  - Chui D
AU  - Alazet S
AU  - Shamsi S
AU  - Mobilio D
AU  - Johnson JW
AU  - Escudero L
AU  - Vandevoorde K
AU  - Mei L
AU  - Acevedo M
AU  - Sabbatani J
AU  - Kent OA
AU  - Dordahan F
AU  - Yadav A
AU  - MacKay B
AU  - Leguay K
AU  - Berger KJ
AU  - Miletic P
AU  - Zhai K
AU  - Ang P
AU  - Huebner A
AU  - Chafe SC
AU  - Sturino C
AU  - Szychowski J
AU  - Venugopal C
AU  - Mancini J
AU  - Phinney AL
AU  - Magolan J
AU  - Singh SK
PY  - 2026
JO  - Proceedings of the National Academy of Sciences of the United States of America
DO  - 10.1073/pnas.2603440123
UR  - https://doi.org/10.1073/pnas.2603440123
ER  - 

APA

AM, K., E, A., S, Z., M, P., D, C., S, A., S, S., D, M., JW, J., L, E., K, V., L, M., M, A., J, S., OA, K., F, D., A, Y., B, M., K, L., KJ, B., P, M., K, Z., P, A., A, H., SC, C., C, S., J, S., C, V., J, M., AL, P., J, M., & SK, S. (2026). Selectively targeting inosine monophosphate dehydrogenase-2 impairs brain metastatic potential while preserving immune cell function.. Proceedings of the National Academy of Sciences of the United States of America. https://doi.org/10.1073/pnas.2603440123

Source records