Multiscale Brownian dynamics simulations reveal effects of macromolecular crowding on protein-ligand association.

Beccaria R, Muñiz-Chicharro A, Wade RC.

DOI: 10.1073/pnas.2617950123
Published: 2026-10-30
Container: Proc Natl Acad Sci U S A
Publisher: Not recorded
Open access: yes

Credibility signals

limited evidence Score 45/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

cautionDOI registered: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
cautionDOI resolves: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
supportingOpen access status: Normalized open-access status: open. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1073/pnas.2617950123,
  title = {Multiscale Brownian dynamics simulations reveal effects of macromolecular crowding on protein-ligand association.},
  author = {Beccaria R and  Muñiz-Chicharro A and  Wade RC.},
  year = {2026},
  journal = {Proc Natl Acad Sci U S A},
  doi = {10.1073/pnas.2617950123},
  url = {https://doi.org/10.1073/pnas.2617950123}
}

RIS

TY  - JOUR
TI  - Multiscale Brownian dynamics simulations reveal effects of macromolecular crowding on protein-ligand association.
AU  - Beccaria R
AU  -  Muñiz-Chicharro A
AU  -  Wade RC.
PY  - 2026
JO  - Proc Natl Acad Sci U S A
DO  - 10.1073/pnas.2617950123
UR  - https://doi.org/10.1073/pnas.2617950123
ER  -

APA

R, B., A, M., & RC., W. (2026). Multiscale Brownian dynamics simulations reveal effects of macromolecular crowding on protein-ligand association.. Proc Natl Acad Sci U S A. https://doi.org/10.1073/pnas.2617950123

Source records

europe-pmc · retrieved 2026-11-10T10:01:58.144Z