Conformational switch of NPC1 epitomizes a lumen-to-membrane alternating access model for nonpolar substrates.

Wu X, Dehghani-Ghahnaviyeh S, Rasouli A, Malona JA, Antalek M, Jones LH, Fan X, Peng A, Tajkhorshid E, Qian H, Yan N

Open source

DOI
10.1073/pnas.2620484123
Published
2026 Oct 13
Container
Proceedings of the National Academy of Sciences of the United States of America
Publisher
Not recorded
Open access
yes

Credibility signals

limited evidence Score 45/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

Cite this work

BibTeX

@article{allodium:10.1073/pnas.2620484123,
  title = {Conformational switch of NPC1 epitomizes a lumen-to-membrane alternating access model for nonpolar substrates.},
  author = {Wu X and Dehghani-Ghahnaviyeh S and Rasouli A and Malona JA and Antalek M and Jones LH and Fan X and Peng A and Tajkhorshid E and Qian H and Yan N},
  year = {2026},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  doi = {10.1073/pnas.2620484123},
  url = {https://doi.org/10.1073/pnas.2620484123}
}

RIS

TY  - JOUR
TI  - Conformational switch of NPC1 epitomizes a lumen-to-membrane alternating access model for nonpolar substrates.
AU  - Wu X
AU  - Dehghani-Ghahnaviyeh S
AU  - Rasouli A
AU  - Malona JA
AU  - Antalek M
AU  - Jones LH
AU  - Fan X
AU  - Peng A
AU  - Tajkhorshid E
AU  - Qian H
AU  - Yan N
PY  - 2026
JO  - Proceedings of the National Academy of Sciences of the United States of America
DO  - 10.1073/pnas.2620484123
UR  - https://doi.org/10.1073/pnas.2620484123
ER  - 

APA

X, W., S, D., A, R., JA, M., M, A., LH, J., X, F., A, P., E, T., H, Q., & N, Y. (2026). Conformational switch of NPC1 epitomizes a lumen-to-membrane alternating access model for nonpolar substrates.. Proceedings of the National Academy of Sciences of the United States of America. https://doi.org/10.1073/pnas.2620484123

Source records