Tumors with TSC mutations are sensitive to CDK7 inhibition through NRF2 and glutathione depletion.

Zarei M, Du H, Nassar AH, Yan RE, Giannikou K, Johnson SH, Lam HC, Henske EP, Wang Y, Zhang T, Asara J, Kwiatkowski DJ

DOI: 10.1084/jem.20190251
Published: 2019 Nov 4
Container: The Journal of experimental medicine
Publisher: Not recorded
Open access: yes

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Cite this work

BibTeX

@article{allodium:10.1084/jem.20190251,
  title = {Tumors with TSC mutations are sensitive to CDK7 inhibition through NRF2 and glutathione depletion.},
  author = {Zarei M and Du H and Nassar AH and Yan RE and Giannikou K and Johnson SH and Lam HC and Henske EP and Wang Y and Zhang T and Asara J and Kwiatkowski DJ},
  year = {2019},
  journal = {The Journal of experimental medicine},
  doi = {10.1084/jem.20190251},
  url = {https://doi.org/10.1084/jem.20190251}
}

RIS

TY  - JOUR
TI  - Tumors with TSC mutations are sensitive to CDK7 inhibition through NRF2 and glutathione depletion.
AU  - Zarei M
AU  - Du H
AU  - Nassar AH
AU  - Yan RE
AU  - Giannikou K
AU  - Johnson SH
AU  - Lam HC
AU  - Henske EP
AU  - Wang Y
AU  - Zhang T
AU  - Asara J
AU  - Kwiatkowski DJ
PY  - 2019
JO  - The Journal of experimental medicine
DO  - 10.1084/jem.20190251
UR  - https://doi.org/10.1084/jem.20190251
ER  -

APA

M, Z., H, D., AH, N., RE, Y., K, G., SH, J., HC, L., EP, H., Y, W., T, Z., J, A., & DJ, K. (2019). Tumors with TSC mutations are sensitive to CDK7 inhibition through NRF2 and glutathione depletion.. The Journal of experimental medicine. https://doi.org/10.1084/jem.20190251

Source records

pubmed · retrieved 2026-09-25T01:50:12.375Z