Development of SDP0505: a first-in-class HER3 × c-Met bispecific ADC, demonstrates potent antitumor activity in EGFR TKI-resistant NSCLC, CRC, and beyond

Li-Min Wang, Changyong Yang, Simeng Chen, Xing Sun, Yunan Tian, Jieqiong Zhang, Xiaomeng Gao, Dan Li, Wei Zhang, Yali Hu, Jimin Yuan, Qumiao Xu, Xiyang Liu, Long Zhang, Qianqian Yu, Cheng Liao

Open source

DOI
10.1093/abt/tbag015
Published
2026-04-01
Container
Antibody Therapeutics
Publisher
Oxford University Press (OUP)
Open access
unknown

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BibTeX

@article{allodium:10.1093/abt/tbag015,
  title = {Development of SDP0505: a first-in-class HER3 × c-Met bispecific ADC, demonstrates potent antitumor activity in EGFR TKI-resistant NSCLC, CRC, and beyond},
  author = {Li-Min Wang and Changyong Yang and Simeng Chen and Xing Sun and Yunan Tian and Jieqiong Zhang and Xiaomeng Gao and Dan Li and Wei Zhang and Yali Hu and Jimin Yuan and Qumiao Xu and Xiyang Liu and Long Zhang and Qianqian Yu and Cheng Liao},
  year = {2026},
  journal = {Antibody Therapeutics},
  doi = {10.1093/abt/tbag015},
  url = {https://doi.org/10.1093/abt/tbag015}
}

RIS

TY  - JOUR
TI  - Development of SDP0505: a first-in-class HER3 × c-Met bispecific ADC, demonstrates potent antitumor activity in EGFR TKI-resistant NSCLC, CRC, and beyond
AU  - Li-Min Wang
AU  - Changyong Yang
AU  - Simeng Chen
AU  - Xing Sun
AU  - Yunan Tian
AU  - Jieqiong Zhang
AU  - Xiaomeng Gao
AU  - Dan Li
AU  - Wei Zhang
AU  - Yali Hu
AU  - Jimin Yuan
AU  - Qumiao Xu
AU  - Xiyang Liu
AU  - Long Zhang
AU  - Qianqian Yu
AU  - Cheng Liao
PY  - 2026
JO  - Antibody Therapeutics
DO  - 10.1093/abt/tbag015
UR  - https://doi.org/10.1093/abt/tbag015
ER  - 

APA

Wang, L., Yang, C., Chen, S., Sun, X., Tian, Y., Zhang, J., Gao, X., Li, D., Zhang, W., Hu, Y., Yuan, J., Xu, Q., Liu, X., Zhang, L., Yu, Q., & Liao, C. (2026). Development of SDP0505: a first-in-class HER3 × c-Met bispecific ADC, demonstrates potent antitumor activity in EGFR TKI-resistant NSCLC, CRC, and beyond. Antibody Therapeutics. https://doi.org/10.1093/abt/tbag015

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