COCA: a randomized Bayesian design integrating dose optimization and component contribution assessment for combination therapies.

Chi X, Lin R, Yuan Y

DOI: 10.1093/biomtc/ujaf077
Published: 2025 Apr 2
Container: Biometrics
Publisher: Not recorded
Open access: yes

Credibility signals

limited evidence Score 45/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

cautionDOI registered: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
cautionDOI resolves: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
supportingOpen access status: Normalized open-access status: open. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1093/biomtc/ujaf077,
  title = {COCA: a randomized Bayesian design integrating dose optimization and component contribution assessment for combination therapies.},
  author = {Chi X and Lin R and Yuan Y},
  year = {2025},
  journal = {Biometrics},
  doi = {10.1093/biomtc/ujaf077},
  url = {https://doi.org/10.1093/biomtc/ujaf077}
}

RIS

TY  - JOUR
TI  - COCA: a randomized Bayesian design integrating dose optimization and component contribution assessment for combination therapies.
AU  - Chi X
AU  - Lin R
AU  - Yuan Y
PY  - 2025
JO  - Biometrics
DO  - 10.1093/biomtc/ujaf077
UR  - https://doi.org/10.1093/biomtc/ujaf077
ER  -

APA

X, C., R, L., & Y, Y. (2025). COCA: a randomized Bayesian design integrating dose optimization and component contribution assessment for combination therapies.. Biometrics. https://doi.org/10.1093/biomtc/ujaf077

Source records

pubmed · retrieved 2026-09-25T20:53:02.954Z