Direct Oral Challenge for Penicillin Allergy: A Hospital Implementation Evaluation Via the International Network of Antibiotic Allergy Nations (iNAAN) Study

Elise A Mitri, Sara Vogrin, Camille Paynter, Luke R Fletcher, Jonny Peter, Neil Powell, Sara Barnes, Philip H Li, Ana Maria Copaescu, Nicholas A Turner, Fiona James, Richard Sullivan, Maryam Sherkat Masoum, Matthew Rawlins, Geoff Mackay, Benjamin J Smith, Patricia Kilfoyle, Daniel Forster, Morgan Rose, Raquel Cowan, Kylie Alcorn, Anna Brischetto, Andrew Mahony, Andrew Redmond, Arindam Chakravorty, Zaal Meher-Homji, Chino Yuson, Simeon Crawford, Greg Weeks, Sasheela Sri La Sri Ponnampalavanar, Constance Katelaris, Priscilla Tran, Jennifer O’Hern, Jack Godsell, Trisha N Peel, Indy Sandaradura, David New, Candice Holland, Tim Cutfield, Sarah Coghill, Caitlin Hand, Jacob Williams, Jaclyn Bishop, Belinda Lambros, Cascia Day, Courtney Ierano, Natasha E Holmes, Jason A Roberts, Suran L Fernando, Marlena Klaic, Jason A Trubiano, Unknown, Kyra Chua, Joseph De Luca, Gemma Reynolds, Evelyn Andrews, Daniel Lapirow, Abby Douglas, Tanya Crichton, Kate Guy, Jessica Jarvis, Tapiwa Rusike, Benjamin Bowen, Martin Keen, Suman Adhikari, Sara Nobrega, Ekua Brenu, Rachael Roberts, Lilian Whelan, Romeo Torres, Chloe Edwards, Laura Bywater, Jamma Li, Therese Boyle, Melanie Figtree, Jessica Bui, Christy El-Khoury, Claire Italiano, Elizabeth Leahy, Emily Heke, Antje Lutjen, Kevin Nguyen, Marsus Pumar, Mittal Patel, Madonna Khreish, Nazanin Khorshidi, Amanda Nichols, Maria Deetlefs, Marshe Maharaj, Cathryn McDougall, Jason Fok, Frank Thien, Stephen Guy, Kylie D’Arcy-Evans, John Dyer, Melinda Jiang, Saima Ahmad, Janice Chiang, Alicia Neels, Callum Maggs, Caroline Bartolo, Nicholas Ah Yui, Karen Lim, Kathryn Wilks, Sarah Kingscote, Lisa Course, Kate Morton, Michelle Donohue, Jack Cross, Samuel Smith, Philip Tibbits, Jenny Park, Gabrielle Chau, Lawrence Ong, Sanjay Swaminathan, Sarah Keady, Lakshana Kalatharan, Raelene Vine, Judy Lamb, Jenny Wan Sai Cheong, David Brownridge, David Kong, Michael Loftus, Jodi Poole, Leeanne Atkinson, Amrita Ronnachit, Frederick Lee, Peter Bradhurst, Alex Stoyanov, Nicholas Urriola, Lisa Horgan, Karen Wells, Kristine Millar, Sophie Briggs, Chloe Bishop, Joseph Doyle, Rachael Leng, Esha Tamrakar, Kelly Cairns, Ng Rong Xiang, Anjanna Kukreja, Sheron Goh Sir Loon, Ong Hang Cheng, Bushra Binti Megat Johari, Sazali Basri, Ng Sin Hui, Tan Yee Ann, Ho Ai Wui, Jacky Richards, Daniel Hearsey, Nicola Leigh, Elizabeth Haigh, Marie Thomas, Helen Winn, Tamsyn Lewis, Angie Gray, Jane Williams, Sophie Weeks, Amanda Pritchard, Owen O’Reilly, Nathan Ratnam, Shamika Ratnayake, Hoan Dang, Sarah Risdale, Kim Ta, Alice Young, Jacqueline can der Meulen, Rocky Shi, Jane Wong, Valerie Chiang, Gordon Chu, James Hooi, Moneerah Algassim, Adhora Mir, Rachael Wiedmann, Rebekah Wrenn, Natalie Harris, Amy Mackowiak, Karen Watt, Sylvia White, Jacob Griffiths, Katie Jodrell, Michaela Lucas, Benjamin Mulo, Astrid Arellano, Christopher Kleeman, Kate Grogan, Steven Tong, Samantha Chan, Kasha Singh, Douglas Johnson, Kymble Spriggs, Samuel Thorburn, Catherine Fitzpatrick, Jessie Zhou, Karen Giang, Christina Vytilingam, Amanda Jackson, Maureen Turner, Javier Haurat, Wisam Abdelaziz

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DOI
10.1093/cid/ciag083
Published
2026-04-01
Container
Clinical Infectious Diseases
Publisher
Oxford University Press (OUP)
Open access
unknown

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@article{allodium:10.1093/cid/ciag083,
  title = {Direct Oral Challenge for Penicillin Allergy: A Hospital Implementation Evaluation Via the International Network of Antibiotic Allergy Nations (iNAAN) Study},
  author = {Elise A Mitri and Sara Vogrin and Camille Paynter and Luke R Fletcher and Jonny Peter and Neil Powell and Sara Barnes and Philip H Li and Ana Maria Copaescu and Nicholas A Turner and Fiona James and Richard Sullivan and Maryam Sherkat Masoum and Matthew Rawlins and Geoff Mackay and Benjamin J Smith and Patricia Kilfoyle and Daniel Forster and Morgan Rose and Raquel Cowan and Kylie Alcorn and Anna Brischetto and Andrew Mahony and Andrew Redmond and Arindam Chakravorty and Zaal Meher-Homji and Chino Yuson and Simeon Crawford and Greg Weeks and Sasheela Sri La Sri Ponnampalavanar and Constance Katelaris and Priscilla Tran and Jennifer O’Hern and Jack Godsell and Trisha N Peel and Indy Sandaradura and David New and Candice Holland and Tim Cutfield and Sarah Coghill and Caitlin Hand and Jacob Williams and Jaclyn Bishop and Belinda Lambros and Cascia Day and Courtney Ierano and Natasha E Holmes and Jason A Roberts and Suran L Fernando and Marlena Klaic and Jason A Trubiano and Unknown and Kyra Chua and Joseph De Luca and Gemma Reynolds and Evelyn Andrews and Daniel Lapirow and Abby Douglas and Tanya Crichton and Kate Guy and Jessica Jarvis and Tapiwa Rusike and Benjamin Bowen and Martin Keen and Suman Adhikari and Sara Nobrega and Ekua Brenu and Rachael Roberts and Lilian Whelan and Romeo Torres and Chloe Edwards and Laura Bywater and Jamma Li and Therese Boyle and Melanie Figtree and Jessica Bui and Christy El-Khoury and Claire Italiano and Elizabeth Leahy and Emily Heke and Antje Lutjen and Kevin Nguyen and Marsus Pumar and Mittal Patel and Madonna Khreish and Nazanin Khorshidi and Amanda Nichols and Maria Deetlefs and Marshe Maharaj and Cathryn McDougall and Jason Fok and Frank Thien and Stephen Guy and Kylie D’Arcy-Evans and John Dyer and Melinda Jiang and Saima Ahmad and Janice Chiang and Alicia Neels and Callum Maggs and Caroline Bartolo and Nicholas Ah Yui and Karen Lim and Kathryn Wilks and Sarah Kingscote and Lisa Course and Kate Morton and Michelle Donohue and Jack Cross and Samuel Smith and Philip Tibbits and Jenny Park and Gabrielle Chau and Lawrence Ong and Sanjay Swaminathan and Sarah Keady and Lakshana Kalatharan and Raelene Vine and Judy Lamb and Jenny Wan Sai Cheong and David Brownridge and David Kong and Michael Loftus and Jodi Poole and Leeanne Atkinson and Amrita Ronnachit and Frederick Lee and Peter Bradhurst and Alex Stoyanov and Nicholas Urriola and Lisa Horgan and Karen Wells and Kristine Millar and Sophie Briggs and Chloe Bishop and Joseph Doyle and Rachael Leng and Esha Tamrakar and Kelly Cairns and Ng Rong Xiang and Anjanna Kukreja and Sheron Goh Sir Loon and Ong Hang Cheng and Bushra Binti Megat Johari and Sazali Basri and Ng Sin Hui and Tan Yee Ann and Ho Ai Wui and Jacky Richards and Daniel Hearsey and Nicola Leigh and Elizabeth Haigh and Marie Thomas and Helen Winn and Tamsyn Lewis and Angie Gray and Jane Williams and Sophie Weeks and Amanda Pritchard and Owen O’Reilly and Nathan Ratnam and Shamika Ratnayake and Hoan Dang and Sarah Risdale and Kim Ta and Alice Young and Jacqueline can der Meulen and Rocky Shi and Jane Wong and Valerie Chiang and Gordon Chu and James Hooi and Moneerah Algassim and Adhora Mir and Rachael Wiedmann and Rebekah Wrenn and Natalie Harris and Amy Mackowiak and Karen Watt and Sylvia White and Jacob Griffiths and Katie Jodrell and Michaela Lucas and Benjamin Mulo and Astrid Arellano and Christopher Kleeman and Kate Grogan and Steven Tong and Samantha Chan and Kasha Singh and Douglas Johnson and Kymble Spriggs and Samuel Thorburn and Catherine Fitzpatrick and Jessie Zhou and Karen Giang and Christina Vytilingam and Amanda Jackson and Maureen Turner and Javier Haurat and Wisam Abdelaziz},
  year = {2026},
  journal = {Clinical Infectious Diseases},
  doi = {10.1093/cid/ciag083},
  url = {https://doi.org/10.1093/cid/ciag083}
}

RIS

TY  - JOUR
TI  - Direct Oral Challenge for Penicillin Allergy: A Hospital Implementation Evaluation Via the International Network of Antibiotic Allergy Nations (iNAAN) Study
AU  - Elise A Mitri
AU  - Sara Vogrin
AU  - Camille Paynter
AU  - Luke R Fletcher
AU  - Jonny Peter
AU  - Neil Powell
AU  - Sara Barnes
AU  - Philip H Li
AU  - Ana Maria Copaescu
AU  - Nicholas A Turner
AU  - Fiona James
AU  - Richard Sullivan
AU  - Maryam Sherkat Masoum
AU  - Matthew Rawlins
AU  - Geoff Mackay
AU  - Benjamin J Smith
AU  - Patricia Kilfoyle
AU  - Daniel Forster
AU  - Morgan Rose
AU  - Raquel Cowan
AU  - Kylie Alcorn
AU  - Anna Brischetto
AU  - Andrew Mahony
AU  - Andrew Redmond
AU  - Arindam Chakravorty
AU  - Zaal Meher-Homji
AU  - Chino Yuson
AU  - Simeon Crawford
AU  - Greg Weeks
AU  - Sasheela Sri La Sri Ponnampalavanar
AU  - Constance Katelaris
AU  - Priscilla Tran
AU  - Jennifer O’Hern
AU  - Jack Godsell
AU  - Trisha N Peel
AU  - Indy Sandaradura
AU  - David New
AU  - Candice Holland
AU  - Tim Cutfield
AU  - Sarah Coghill
AU  - Caitlin Hand
AU  - Jacob Williams
AU  - Jaclyn Bishop
AU  - Belinda Lambros
AU  - Cascia Day
AU  - Courtney Ierano
AU  - Natasha E Holmes
AU  - Jason A Roberts
AU  - Suran L Fernando
AU  - Marlena Klaic
AU  - Jason A Trubiano
AU  - Unknown
AU  - Kyra Chua
AU  - Joseph De Luca
AU  - Gemma Reynolds
AU  - Evelyn Andrews
AU  - Daniel Lapirow
AU  - Abby Douglas
AU  - Tanya Crichton
AU  - Kate Guy
AU  - Jessica Jarvis
AU  - Tapiwa Rusike
AU  - Benjamin Bowen
AU  - Martin Keen
AU  - Suman Adhikari
AU  - Sara Nobrega
AU  - Ekua Brenu
AU  - Rachael Roberts
AU  - Lilian Whelan
AU  - Romeo Torres
AU  - Chloe Edwards
AU  - Laura Bywater
AU  - Jamma Li
AU  - Therese Boyle
AU  - Melanie Figtree
AU  - Jessica Bui
AU  - Christy El-Khoury
AU  - Claire Italiano
AU  - Elizabeth Leahy
AU  - Emily Heke
AU  - Antje Lutjen
AU  - Kevin Nguyen
AU  - Marsus Pumar
AU  - Mittal Patel
AU  - Madonna Khreish
AU  - Nazanin Khorshidi
AU  - Amanda Nichols
AU  - Maria Deetlefs
AU  - Marshe Maharaj
AU  - Cathryn McDougall
AU  - Jason Fok
AU  - Frank Thien
AU  - Stephen Guy
AU  - Kylie D’Arcy-Evans
AU  - John Dyer
AU  - Melinda Jiang
AU  - Saima Ahmad
AU  - Janice Chiang
AU  - Alicia Neels
AU  - Callum Maggs
AU  - Caroline Bartolo
AU  - Nicholas Ah Yui
AU  - Karen Lim
AU  - Kathryn Wilks
AU  - Sarah Kingscote
AU  - Lisa Course
AU  - Kate Morton
AU  - Michelle Donohue
AU  - Jack Cross
AU  - Samuel Smith
AU  - Philip Tibbits
AU  - Jenny Park
AU  - Gabrielle Chau
AU  - Lawrence Ong
AU  - Sanjay Swaminathan
AU  - Sarah Keady
AU  - Lakshana Kalatharan
AU  - Raelene Vine
AU  - Judy Lamb
AU  - Jenny Wan Sai Cheong
AU  - David Brownridge
AU  - David Kong
AU  - Michael Loftus
AU  - Jodi Poole
AU  - Leeanne Atkinson
AU  - Amrita Ronnachit
AU  - Frederick Lee
AU  - Peter Bradhurst
AU  - Alex Stoyanov
AU  - Nicholas Urriola
AU  - Lisa Horgan
AU  - Karen Wells
AU  - Kristine Millar
AU  - Sophie Briggs
AU  - Chloe Bishop
AU  - Joseph Doyle
AU  - Rachael Leng
AU  - Esha Tamrakar
AU  - Kelly Cairns
AU  - Ng Rong Xiang
AU  - Anjanna Kukreja
AU  - Sheron Goh Sir Loon
AU  - Ong Hang Cheng
AU  - Bushra Binti Megat Johari
AU  - Sazali Basri
AU  - Ng Sin Hui
AU  - Tan Yee Ann
AU  - Ho Ai Wui
AU  - Jacky Richards
AU  - Daniel Hearsey
AU  - Nicola Leigh
AU  - Elizabeth Haigh
AU  - Marie Thomas
AU  - Helen Winn
AU  - Tamsyn Lewis
AU  - Angie Gray
AU  - Jane Williams
AU  - Sophie Weeks
AU  - Amanda Pritchard
AU  - Owen O’Reilly
AU  - Nathan Ratnam
AU  - Shamika Ratnayake
AU  - Hoan Dang
AU  - Sarah Risdale
AU  - Kim Ta
AU  - Alice Young
AU  - Jacqueline can der Meulen
AU  - Rocky Shi
AU  - Jane Wong
AU  - Valerie Chiang
AU  - Gordon Chu
AU  - James Hooi
AU  - Moneerah Algassim
AU  - Adhora Mir
AU  - Rachael Wiedmann
AU  - Rebekah Wrenn
AU  - Natalie Harris
AU  - Amy Mackowiak
AU  - Karen Watt
AU  - Sylvia White
AU  - Jacob Griffiths
AU  - Katie Jodrell
AU  - Michaela Lucas
AU  - Benjamin Mulo
AU  - Astrid Arellano
AU  - Christopher Kleeman
AU  - Kate Grogan
AU  - Steven Tong
AU  - Samantha Chan
AU  - Kasha Singh
AU  - Douglas Johnson
AU  - Kymble Spriggs
AU  - Samuel Thorburn
AU  - Catherine Fitzpatrick
AU  - Jessie Zhou
AU  - Karen Giang
AU  - Christina Vytilingam
AU  - Amanda Jackson
AU  - Maureen Turner
AU  - Javier Haurat
AU  - Wisam Abdelaziz
PY  - 2026
JO  - Clinical Infectious Diseases
DO  - 10.1093/cid/ciag083
UR  - https://doi.org/10.1093/cid/ciag083
ER  - 

APA

Mitri, E. A., Vogrin, S., Paynter, C., Fletcher, L. R., Peter, J., Powell, N., Barnes, S., Li, P. H., Copaescu, A. M., Turner, N. A., James, F., Sullivan, R., Masoum, M. S., Rawlins, M., Mackay, G., Smith, B. J., Kilfoyle, P., Forster, D., Rose, M., Cowan, R., Alcorn, K., Brischetto, A., Mahony, A., Redmond, A., Chakravorty, A., Meher-Homji, Z., Yuson, C., Crawford, S., Weeks, G., Ponnampalavanar, S. S. L. S., Katelaris, C., Tran, P., O’Hern, J., Godsell, J., Peel, T. N., Sandaradura, I., New, D., Holland, C., Cutfield, T., Coghill, S., Hand, C., Williams, J., Bishop, J., Lambros, B., Day, C., Ierano, C., Holmes, N. E., Roberts, J. A., Fernando, S. L., Klaic, M., Trubiano, J. A., Unknown, Chua, K., Luca, J. D., Reynolds, G., Andrews, E., Lapirow, D., Douglas, A., Crichton, T., Guy, K., Jarvis, J., Rusike, T., Bowen, B., Keen, M., Adhikari, S., Nobrega, S., Brenu, E., Roberts, R., Whelan, L., Torres, R., Edwards, C., Bywater, L., Li, J., Boyle, T., Figtree, M., Bui, J., El-Khoury, C., Italiano, C., Leahy, E., Heke, E., Lutjen, A., Nguyen, K., Pumar, M., Patel, M., Khreish, M., Khorshidi, N., Nichols, A., Deetlefs, M., Maharaj, M., McDougall, C., Fok, J., Thien, F., Guy, S., D’Arcy-Evans, K., Dyer, J., Jiang, M., Ahmad, S., Chiang, J., Neels, A., Maggs, C., Bartolo, C., Yui, N. A., Lim, K., Wilks, K., Kingscote, S., Course, L., Morton, K., Donohue, M., Cross, J., Smith, S., Tibbits, P., Park, J., Chau, G., Ong, L., Swaminathan, S., Keady, S., Kalatharan, L., Vine, R., Lamb, J., Cheong, J. W. S., Brownridge, D., Kong, D., Loftus, M., Poole, J., Atkinson, L., Ronnachit, A., Lee, F., Bradhurst, P., Stoyanov, A., Urriola, N., Horgan, L., Wells, K., Millar, K., Briggs, S., Bishop, C., Doyle, J., Leng, R., Tamrakar, E., Cairns, K., Xiang, N. R., Kukreja, A., Loon, S. G. S., Cheng, O. H., Johari, B. B. M., Basri, S., Hui, N. S., Ann, T. Y., Wui, H. A., Richards, J., Hearsey, D., Leigh, N., Haigh, E., Thomas, M., Winn, H., Lewis, T., Gray, A., Williams, J., Weeks, S., Pritchard, A., O’Reilly, O., Ratnam, N., Ratnayake, S., Dang, H., Risdale, S., Ta, K., Young, A., Meulen, J. C. D., Shi, R., Wong, J., Chiang, V., Chu, G., Hooi, J., Algassim, M., Mir, A., Wiedmann, R., Wrenn, R., Harris, N., Mackowiak, A., Watt, K., White, S., Griffiths, J., Jodrell, K., Lucas, M., Mulo, B., Arellano, A., Kleeman, C., Grogan, K., Tong, S., Chan, S., Singh, K., Johnson, D., Spriggs, K., Thorburn, S., Fitzpatrick, C., Zhou, J., Giang, K., Vytilingam, C., Jackson, A., Turner, M., Haurat, J., & Abdelaziz, W. (2026). Direct Oral Challenge for Penicillin Allergy: A Hospital Implementation Evaluation Via the International Network of Antibiotic Allergy Nations (iNAAN) Study. Clinical Infectious Diseases. https://doi.org/10.1093/cid/ciag083

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