Targeting RUNX1 protects against diastolic dysfunction in a two-hit mouse model of heart failure with preserved ejection fraction.

Elbassioni AAM, Raheem AA, Song J, Johnston AS, Trivett C, Lin H, Zhang H, Bradley A, Higgins E, Thomson CR, Mooney L, Koay YC, O'Toole D, Herzyk P, Nixon C, Blyth K, Hughes M, Al-Attar N, O'Sullivan JF, Lang NN, Berry C, Braun T, Schiattarella GG, Giacca M, McBride MW, Nicklin SA, Cameron ER, Loughrey CM, MacDonald EA

Open source

DOI: 10.1093/cvr/cvag106
Published: 2026 Jul 11
Container: Cardiovascular research
Publisher: Not recorded
Open access: yes

Credibility signals

limited evidence Score 45/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

cautionDOI registered: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
cautionDOI resolves: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
supportingOpen access status: Normalized open-access status: open. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1093/cvr/cvag106,
  title = {Targeting RUNX1 protects against diastolic dysfunction in a two-hit mouse model of heart failure with preserved ejection fraction.},
  author = {Elbassioni AAM and Raheem AA and Song J and Johnston AS and Trivett C and Lin H and Zhang H and Bradley A and Higgins E and Thomson CR and Mooney L and Koay YC and O'Toole D and Herzyk P and Nixon C and Blyth K and Hughes M and Al-Attar N and O'Sullivan JF and Lang NN and Berry C and Braun T and Schiattarella GG and Giacca M and McBride MW and Nicklin SA and Cameron ER and Loughrey CM and MacDonald EA},
  year = {2026},
  journal = {Cardiovascular research},
  doi = {10.1093/cvr/cvag106},
  url = {https://doi.org/10.1093/cvr/cvag106}
}

RIS

TY  - JOUR
TI  - Targeting RUNX1 protects against diastolic dysfunction in a two-hit mouse model of heart failure with preserved ejection fraction.
AU  - Elbassioni AAM
AU  - Raheem AA
AU  - Song J
AU  - Johnston AS
AU  - Trivett C
AU  - Lin H
AU  - Zhang H
AU  - Bradley A
AU  - Higgins E
AU  - Thomson CR
AU  - Mooney L
AU  - Koay YC
AU  - O'Toole D
AU  - Herzyk P
AU  - Nixon C
AU  - Blyth K
AU  - Hughes M
AU  - Al-Attar N
AU  - O'Sullivan JF
AU  - Lang NN
AU  - Berry C
AU  - Braun T
AU  - Schiattarella GG
AU  - Giacca M
AU  - McBride MW
AU  - Nicklin SA
AU  - Cameron ER
AU  - Loughrey CM
AU  - MacDonald EA
PY  - 2026
JO  - Cardiovascular research
DO  - 10.1093/cvr/cvag106
UR  - https://doi.org/10.1093/cvr/cvag106
ER  -

APA

AAM, E., AA, R., J, S., AS, J., C, T., H, L., H, Z., A, B., E, H., CR, T., L, M., YC, K., D, O., P, H., C, N., K, B., M, H., N, A., JF, O., NN, L., C, B., T, B., GG, S., M, G., MW, M., SA, N., ER, C., CM, L., & EA, M. (2026). Targeting RUNX1 protects against diastolic dysfunction in a two-hit mouse model of heart failure with preserved ejection fraction.. Cardiovascular research. https://doi.org/10.1093/cvr/cvag106

Source records

pubmed · retrieved 2026-09-25T20:27:37.914Z