Bridging preclinical and clinical efficacy of SIK2/SIK3 inhibition in inflammatory bowel disease through integrated murine, patient-derived models, and phase 2a trial-based analyses

Lorenzo Giorio, Steve De Vos, Maikel Luis Colli, Didier Merciris, Eva Vissers, Tommaso Innocenti, Fabrice Kolb, Marc Ferrante, João Guedelha Sabino, Séverine Vermeire, Kaline Arnauts, Bram Verstockt

Open source

DOI
10.1093/ecco-jcc/jjag133
Published
2026-09
Container
Journal of Crohn's and Colitis
Publisher
Oxford University Press (OUP)
Open access
unknown

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BibTeX

@article{allodium:10.1093/ecco-jcc/jjag133,
  title = {Bridging preclinical and clinical efficacy of SIK2/SIK3 inhibition in inflammatory bowel disease through integrated murine, patient-derived models, and phase 2a trial-based analyses},
  author = {Lorenzo Giorio and Steve De Vos and Maikel Luis Colli and Didier Merciris and Eva Vissers and Tommaso Innocenti and Fabrice Kolb and Marc Ferrante and João Guedelha Sabino and Séverine Vermeire and Kaline Arnauts and Bram Verstockt},
  year = {2026},
  journal = {Journal of Crohn's and Colitis},
  doi = {10.1093/ecco-jcc/jjag133},
  url = {https://doi.org/10.1093/ecco-jcc/jjag133}
}

RIS

TY  - JOUR
TI  - Bridging preclinical and clinical efficacy of SIK2/SIK3 inhibition in inflammatory bowel disease through integrated murine, patient-derived models, and phase 2a trial-based analyses
AU  - Lorenzo Giorio
AU  - Steve De Vos
AU  - Maikel Luis Colli
AU  - Didier Merciris
AU  - Eva Vissers
AU  - Tommaso Innocenti
AU  - Fabrice Kolb
AU  - Marc Ferrante
AU  - João Guedelha Sabino
AU  - Séverine Vermeire
AU  - Kaline Arnauts
AU  - Bram Verstockt
PY  - 2026
JO  - Journal of Crohn's and Colitis
DO  - 10.1093/ecco-jcc/jjag133
UR  - https://doi.org/10.1093/ecco-jcc/jjag133
ER  - 

APA

Giorio, L., Vos, S. D., Colli, M. L., Merciris, D., Vissers, E., Innocenti, T., Kolb, F., Ferrante, M., Sabino, J. G., Vermeire, S., Arnauts, K., & Verstockt, B. (2026). Bridging preclinical and clinical efficacy of SIK2/SIK3 inhibition in inflammatory bowel disease through integrated murine, patient-derived models, and phase 2a trial-based analyses. Journal of Crohn's and Colitis. https://doi.org/10.1093/ecco-jcc/jjag133

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