Enhancing validation of case-control omics signatures through "minimalist" single-subject analysis (N-of-1 trials): proof of concept in sepsis.

Wilson LS, Pouladi N, Nelson RF, Middleton EA, Tolley ND, Shabanian M, Kenost C, Campbell RA, Rondina MT, Lussier YA

DOI: 10.1093/jamia/ocag061
Published: 2026 Jul 1
Container: Journal of the American Medical Informatics Association : JAMIA
Publisher: Not recorded
Open access: yes

Credibility signals

limited evidence Score 45/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

cautionDOI registered: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
cautionDOI resolves: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
supportingOpen access status: Normalized open-access status: open. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1093/jamia/ocag061,
  title = {Enhancing validation of case-control omics signatures through "minimalist" single-subject analysis (N-of-1 trials): proof of concept in sepsis.},
  author = {Wilson LS and Pouladi N and Nelson RF and Middleton EA and Tolley ND and Shabanian M and Kenost C and Campbell RA and Rondina MT and Lussier YA},
  year = {2026},
  journal = {Journal of the American Medical Informatics Association : JAMIA},
  doi = {10.1093/jamia/ocag061},
  url = {https://doi.org/10.1093/jamia/ocag061}
}

RIS

TY  - JOUR
TI  - Enhancing validation of case-control omics signatures through "minimalist" single-subject analysis (N-of-1 trials): proof of concept in sepsis.
AU  - Wilson LS
AU  - Pouladi N
AU  - Nelson RF
AU  - Middleton EA
AU  - Tolley ND
AU  - Shabanian M
AU  - Kenost C
AU  - Campbell RA
AU  - Rondina MT
AU  - Lussier YA
PY  - 2026
JO  - Journal of the American Medical Informatics Association : JAMIA
DO  - 10.1093/jamia/ocag061
UR  - https://doi.org/10.1093/jamia/ocag061
ER  -

APA

LS, W., N, P., RF, N., EA, M., ND, T., M, S., C, K., RA, C., MT, R., & YA, L. (2026). Enhancing validation of case-control omics signatures through "minimalist" single-subject analysis (N-of-1 trials): proof of concept in sepsis.. Journal of the American Medical Informatics Association : JAMIA. https://doi.org/10.1093/jamia/ocag061

Source records

pubmed · retrieved 2026-09-25T04:15:22.908Z