Targeting CDK12 disrupts estrogen-receptor chromatin recruitment and ER-MED1 transcription in advanced ER+ breast cancer.
- DOI
- 10.1093/jnci/djaf295
- Published
- 2026 Mar 1
- Container
- Journal of the National Cancer Institute
- Publisher
- Not recorded
- Open access
- yes
Credibility signals
limited evidence Score 45/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.
Show all credibility signals
- cautionDOI registered: No matching Crossref record was present in this response.
- cautionDOI resolves: No matching Crossref record was present in this response.
- not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility.
- not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made.
- not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made.
- not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made.
- not scoredROR affiliation: Not checked or no result supplied; no credibility inference made.
- not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete.
- not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete.
- not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete.
- not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete.
- supportingOpen access status: Normalized open-access status: open.
- not scoredPublication license: Not checked or no result supplied; no credibility inference made.
- not scoredPublication version: A publication version was supplied but is not scored.
- cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty.
Cite this work
BibTeX
@article{allodium:10.1093/jnci/djaf295,
title = {Targeting CDK12 disrupts estrogen-receptor chromatin recruitment and ER-MED1 transcription in advanced ER+ breast cancer.},
author = {Ottaviani D and Ola M and Allotta A and Maati Chaibi Y and Hickey S and Jagust P and Cosgrove N and Cocchiglia S and Bane F and Fallon R and Daly G and Hegarty A and Hudson L and Sheehan K and Kalsi S and Shovlin S and Powell A and Bahl A and Ainscow E and Oesterreich S and Lee AV and Couch FJ and Hill ADK and Varešlija D and Young L},
year = {2026},
journal = {Journal of the National Cancer Institute},
doi = {10.1093/jnci/djaf295},
url = {https://doi.org/10.1093/jnci/djaf295}
}RIS
TY - JOUR TI - Targeting CDK12 disrupts estrogen-receptor chromatin recruitment and ER-MED1 transcription in advanced ER+ breast cancer. AU - Ottaviani D AU - Ola M AU - Allotta A AU - Maati Chaibi Y AU - Hickey S AU - Jagust P AU - Cosgrove N AU - Cocchiglia S AU - Bane F AU - Fallon R AU - Daly G AU - Hegarty A AU - Hudson L AU - Sheehan K AU - Kalsi S AU - Shovlin S AU - Powell A AU - Bahl A AU - Ainscow E AU - Oesterreich S AU - Lee AV AU - Couch FJ AU - Hill ADK AU - Varešlija D AU - Young L PY - 2026 JO - Journal of the National Cancer Institute DO - 10.1093/jnci/djaf295 UR - https://doi.org/10.1093/jnci/djaf295 ER -
APA
D, O., M, O., A, A., Y, M. C., S, H., P, J., N, C., S, C., F, B., R, F., G, D., A, H., L, H., K, S., S, K., S, S., A, P., A, B., E, A., S, O., AV, L., FJ, C., ADK, H., D, V., & L, Y. (2026). Targeting CDK12 disrupts estrogen-receptor chromatin recruitment and ER-MED1 transcription in advanced ER+ breast cancer.. Journal of the National Cancer Institute. https://doi.org/10.1093/jnci/djaf295
Source records
- pubmed · retrieved 2026-09-27T01:30:57.261Z