Intracerebroventricular B7-H3-targeting CAR T cells for non-pontine DMG and recurrent/refractory pediatric CNS tumors: a phase 1 trial.

Ronsley R, Huang W, Rohlf E, Seidel K, Brown C, Beebe A, Rawlings-Rhea SD, Lindgren C, Sad T, Crotty EE, Leary SES, Thomsen A, Beckstrom AR, Holtzclaw SL, Hoeppner C, Hurst D, MacQuivey M, Goldstein HE, Browd SR, Hauptman JS, Lee A, Ojemann JG, Wright JN, Albert CM, Pinto N, Gustafson JA, Ho O, Pattabhi S, Summers C, Annesley C, Wendler JN, Gust J, Gardner RA, Park JR, Jensen MC, Vitanza NA

Open source

DOI: 10.1093/neuonc/noag171
Published: 2026 Jul 25
Container: Neuro-oncology
Publisher: Not recorded
Open access: unknown

Credibility signals

limited evidence Score 43/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

cautionDOI registered: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
cautionDOI resolves: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredOpen access status: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1093/neuonc/noag171,
  title = {Intracerebroventricular B7-H3-targeting CAR T cells for non-pontine DMG and recurrent/refractory pediatric CNS tumors: a phase 1 trial.},
  author = {Ronsley R and Huang W and Rohlf E and Seidel K and Brown C and Beebe A and Rawlings-Rhea SD and Lindgren C and Sad T and Crotty EE and Leary SES and Thomsen A and Beckstrom AR and Holtzclaw SL and Hoeppner C and Hurst D and MacQuivey M and Goldstein HE and Browd SR and Hauptman JS and Lee A and Ojemann JG and Wright JN and Albert CM and Pinto N and Gustafson JA and Ho O and Pattabhi S and Summers C and Annesley C and Wendler JN and Gust J and Gardner RA and Park JR and Jensen MC and Vitanza NA},
  year = {2026},
  journal = {Neuro-oncology},
  doi = {10.1093/neuonc/noag171},
  url = {https://doi.org/10.1093/neuonc/noag171}
}

RIS

TY  - JOUR
TI  - Intracerebroventricular B7-H3-targeting CAR T cells for non-pontine DMG and recurrent/refractory pediatric CNS tumors: a phase 1 trial.
AU  - Ronsley R
AU  - Huang W
AU  - Rohlf E
AU  - Seidel K
AU  - Brown C
AU  - Beebe A
AU  - Rawlings-Rhea SD
AU  - Lindgren C
AU  - Sad T
AU  - Crotty EE
AU  - Leary SES
AU  - Thomsen A
AU  - Beckstrom AR
AU  - Holtzclaw SL
AU  - Hoeppner C
AU  - Hurst D
AU  - MacQuivey M
AU  - Goldstein HE
AU  - Browd SR
AU  - Hauptman JS
AU  - Lee A
AU  - Ojemann JG
AU  - Wright JN
AU  - Albert CM
AU  - Pinto N
AU  - Gustafson JA
AU  - Ho O
AU  - Pattabhi S
AU  - Summers C
AU  - Annesley C
AU  - Wendler JN
AU  - Gust J
AU  - Gardner RA
AU  - Park JR
AU  - Jensen MC
AU  - Vitanza NA
PY  - 2026
JO  - Neuro-oncology
DO  - 10.1093/neuonc/noag171
UR  - https://doi.org/10.1093/neuonc/noag171
ER  -

APA

R, R., W, H., E, R., K, S., C, B., A, B., SD, R., C, L., T, S., EE, C., SES, L., A, T., AR, B., SL, H., C, H., D, H., M, M., HE, G., SR, B., JS, H., A, L., JG, O., JN, W., CM, A., N, P., JA, G., O, H., S, P., C, S., C, A., JN, W., J, G., RA, G., JR, P., MC, J., & NA, V. (2026). Intracerebroventricular B7-H3-targeting CAR T cells for non-pontine DMG and recurrent/refractory pediatric CNS tumors: a phase 1 trial.. Neuro-oncology. https://doi.org/10.1093/neuonc/noag171

Source records

pubmed · retrieved 2026-09-26T02:41:50.236Z