Characterizing oxidative metabolites of 6-methylnicotine (6MN; aka Metatine): divergent metabolism from nicotine and identification of urinary biomarkers of exposure

Zhengzhi Xie, Daniel J Conklin, Lexiao Jin, Alexis Miller, Heather Stowers, Jackie Gallagher, Rachel J Keith, Jin Y Chen, Pawel Lorkiewicz

Open source

DOI: 10.1093/toxsci/kfaf107
Published: 2025-07-21
Container: Toxicological Sciences
Publisher: Oxford University Press (OUP)
Open access: unknown

Credibility signals

uncertain Score 64/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

supportingDOI registered: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
supportingDOI resolves: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredOpen access status: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
supportingMetadata completeness: All 6 scored descriptive metadata groups are present. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1093/toxsci/kfaf107,
  title = {Characterizing oxidative metabolites of 6-methylnicotine (6MN; aka Metatine): divergent metabolism from nicotine and identification of urinary biomarkers of exposure},
  author = {Zhengzhi Xie and Daniel J Conklin and Lexiao Jin and Alexis Miller and Heather Stowers and Jackie Gallagher and Rachel J Keith and Jin Y Chen and Pawel Lorkiewicz},
  year = {2025},
  journal = {Toxicological Sciences},
  doi = {10.1093/toxsci/kfaf107},
  url = {https://doi.org/10.1093/toxsci/kfaf107}
}

RIS

TY  - JOUR
TI  - Characterizing oxidative metabolites of 6-methylnicotine (6MN; aka Metatine): divergent metabolism from nicotine and identification of urinary biomarkers of exposure
AU  - Zhengzhi Xie
AU  - Daniel J Conklin
AU  - Lexiao Jin
AU  - Alexis Miller
AU  - Heather Stowers
AU  - Jackie Gallagher
AU  - Rachel J Keith
AU  - Jin Y Chen
AU  - Pawel Lorkiewicz
PY  - 2025
JO  - Toxicological Sciences
DO  - 10.1093/toxsci/kfaf107
UR  - https://doi.org/10.1093/toxsci/kfaf107
ER  -

APA

Xie, Z., Conklin, D. J., Jin, L., Miller, A., Stowers, H., Gallagher, J., Keith, R. J., Chen, J. Y., & Lorkiewicz, P. (2025). Characterizing oxidative metabolites of 6-methylnicotine (6MN; aka Metatine): divergent metabolism from nicotine and identification of urinary biomarkers of exposure. Toxicological Sciences. https://doi.org/10.1093/toxsci/kfaf107

Source records

crossref · retrieved 2026-09-26T00:08:12.105Z