Efficacy and Safety of Remimazolam Tosylate versus Propofol for Sedation of Postoperative Mechanically Ventilated Patients in Intensive Care Units: A Multicenter, Randomized, Single-blind, Noninferiority, Phase 3 Trial

Xiangdong Guan, Ning Liu, Fenghui Lin, Jianbo Yu, Mei Yang, Qianyun Zhou, Kun Chen, Xiangyou Yu, Xiaobo Huang, Jianjun Zhu, Jie Lyu, Chunmei Gui, Zhenjie Hu, Shaopeng Zheng, Bin He, Maojuan Wang, Zhanbiao Yu, Xinglong Ma, Ailian Lv, Jiaqiang Zhang, Jingyuan Xu, Jilu Ye, Jianguo Gong, Xin Tian, Jing Zhou, Fachun Zhou, Li Yu, Wenlong He, Xi Li, Tengrui Yin, Huixin Zhao, Yan Ding, Minying Chen

Open source

DOI: 10.1097/aln.0000000000006047
Published: 2026-03-19
Container: Anesthesiology
Publisher: Ovid Technologies (Wolters Kluwer Health)
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1097/aln.0000000000006047,
  title = {Efficacy and Safety of Remimazolam Tosylate versus Propofol for Sedation of Postoperative Mechanically Ventilated Patients in Intensive Care Units: A Multicenter, Randomized, Single-blind, Noninferiority, Phase 3 Trial},
  author = {Xiangdong Guan and Ning Liu and Fenghui Lin and Jianbo Yu and Mei Yang and Qianyun Zhou and Kun Chen and Xiangyou Yu and Xiaobo Huang and Jianjun Zhu and Jie Lyu and Chunmei Gui and Zhenjie Hu and Shaopeng Zheng and Bin He and Maojuan Wang and Zhanbiao Yu and Xinglong Ma and Ailian Lv and Jiaqiang Zhang and Jingyuan Xu and Jilu Ye and Jianguo Gong and Xin Tian and Jing Zhou and Fachun Zhou and Li Yu and Wenlong He and Xi Li and Tengrui Yin and Huixin Zhao and Yan Ding and Minying Chen},
  year = {2026},
  journal = {Anesthesiology},
  doi = {10.1097/aln.0000000000006047},
  url = {https://doi.org/10.1097/aln.0000000000006047}
}

RIS

TY  - JOUR
TI  - Efficacy and Safety of Remimazolam Tosylate versus Propofol for Sedation of Postoperative Mechanically Ventilated Patients in Intensive Care Units: A Multicenter, Randomized, Single-blind, Noninferiority, Phase 3 Trial
AU  - Xiangdong Guan
AU  - Ning Liu
AU  - Fenghui Lin
AU  - Jianbo Yu
AU  - Mei Yang
AU  - Qianyun Zhou
AU  - Kun Chen
AU  - Xiangyou Yu
AU  - Xiaobo Huang
AU  - Jianjun Zhu
AU  - Jie Lyu
AU  - Chunmei Gui
AU  - Zhenjie Hu
AU  - Shaopeng Zheng
AU  - Bin He
AU  - Maojuan Wang
AU  - Zhanbiao Yu
AU  - Xinglong Ma
AU  - Ailian Lv
AU  - Jiaqiang Zhang
AU  - Jingyuan Xu
AU  - Jilu Ye
AU  - Jianguo Gong
AU  - Xin Tian
AU  - Jing Zhou
AU  - Fachun Zhou
AU  - Li Yu
AU  - Wenlong He
AU  - Xi Li
AU  - Tengrui Yin
AU  - Huixin Zhao
AU  - Yan Ding
AU  - Minying Chen
PY  - 2026
JO  - Anesthesiology
DO  - 10.1097/aln.0000000000006047
UR  - https://doi.org/10.1097/aln.0000000000006047
ER  -

APA

Guan, X., Liu, N., Lin, F., Yu, J., Yang, M., Zhou, Q., Chen, K., Yu, X., Huang, X., Zhu, J., Lyu, J., Gui, C., Hu, Z., Zheng, S., He, B., Wang, M., Yu, Z., Ma, X., Lv, A., Zhang, J., Xu, J., Ye, J., Gong, J., Tian, X., Zhou, J., Zhou, F., Yu, L., He, W., Li, X., Yin, T., Zhao, H., Ding, Y., & Chen, M. (2026). Efficacy and Safety of Remimazolam Tosylate versus Propofol for Sedation of Postoperative Mechanically Ventilated Patients in Intensive Care Units: A Multicenter, Randomized, Single-blind, Noninferiority, Phase 3 Trial. Anesthesiology. https://doi.org/10.1097/aln.0000000000006047

Source records

crossref · retrieved 2026-09-26T07:28:36.355Z