Artificial Liver Support Effectively Removes Immunosuppressive Bile Acids From Circulation in Patients With Severe Liver Failure: A Proof of Concept Study

Julia Leonhardt, Hartmut H.-J. Schmidt, Sebastian Koball, Matthias Dollinger, Christian Wilms, Sophie Neugebauer, Julia Kunze, Michael Kiehntopf, Michael Hinz, Johanna Backhus, Jörg Henschel, Sebastian Klammt, Christoph Sponholz, Adrian Dominik, Steffen Mitzner, Jan Stange, Michael Bauer, Andreas Kortgen

Open source

DOI: 10.1097/cce.0000000000001419
Published: 2026-06
Container: Critical Care Explorations
Publisher: Ovid Technologies (Wolters Kluwer Health)
Open access: unknown

Credibility signals

uncertain Score 64/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

supportingDOI registered: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
supportingDOI resolves: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredOpen access status: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
supportingMetadata completeness: All 6 scored descriptive metadata groups are present. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1097/cce.0000000000001419,
  title = {Artificial Liver Support Effectively Removes Immunosuppressive Bile Acids From Circulation in Patients With Severe Liver Failure: A Proof of Concept Study},
  author = {Julia Leonhardt and Hartmut H.-J. Schmidt and Sebastian Koball and Matthias Dollinger and Christian Wilms and Sophie Neugebauer and Julia Kunze and Michael Kiehntopf and Michael Hinz and Johanna Backhus and Jörg Henschel and Sebastian Klammt and Christoph Sponholz and Adrian Dominik and Steffen Mitzner and Jan Stange and Michael Bauer and Andreas Kortgen},
  year = {2026},
  journal = {Critical Care Explorations},
  doi = {10.1097/cce.0000000000001419},
  url = {https://doi.org/10.1097/cce.0000000000001419}
}

RIS

TY  - JOUR
TI  - Artificial Liver Support Effectively Removes Immunosuppressive Bile Acids From Circulation in Patients With Severe Liver Failure: A Proof of Concept Study
AU  - Julia Leonhardt
AU  - Hartmut H.-J. Schmidt
AU  - Sebastian Koball
AU  - Matthias Dollinger
AU  - Christian Wilms
AU  - Sophie Neugebauer
AU  - Julia Kunze
AU  - Michael Kiehntopf
AU  - Michael Hinz
AU  - Johanna Backhus
AU  - Jörg Henschel
AU  - Sebastian Klammt
AU  - Christoph Sponholz
AU  - Adrian Dominik
AU  - Steffen Mitzner
AU  - Jan Stange
AU  - Michael Bauer
AU  - Andreas Kortgen
PY  - 2026
JO  - Critical Care Explorations
DO  - 10.1097/cce.0000000000001419
UR  - https://doi.org/10.1097/cce.0000000000001419
ER  -

APA

Leonhardt, J., Schmidt, H. H., Koball, S., Dollinger, M., Wilms, C., Neugebauer, S., Kunze, J., Kiehntopf, M., Hinz, M., Backhus, J., Henschel, J., Klammt, S., Sponholz, C., Dominik, A., Mitzner, S., Stange, J., Bauer, M., & Kortgen, A. (2026). Artificial Liver Support Effectively Removes Immunosuppressive Bile Acids From Circulation in Patients With Severe Liver Failure: A Proof of Concept Study. Critical Care Explorations. https://doi.org/10.1097/cce.0000000000001419

Source records

crossref · retrieved 2026-09-26T11:30:59.858Z