Efficacy and Safety of Sodium-Glucose Cotransporter-2 Inhibitors for Heart Failure in Children and Adolescents: A Single-Arm and Pairwise Systematic Review and Meta-Analysis with GRADE Assessment of the Evidence

Leen Adel Aldossary, Raghad Mamdouh Alanazi, Rana Motlk Almutairi, Tayba Abdulrahman Mugibel, Karen Deaa Ghanam, Robaiya Awadh Robaiya Ben-obaidellah, Khloud Awadh Mohammed, Asrar Abdulkarim Alharbi, Joudi Ali Almahabi, Rawan Abdullah Saad Alzahrani, Hala Salim Abu-Qasem, Mohamed Hamouda Elkasaby, Omer A. Algonaid, William H. Frishman, Wilbert S. Aronow

Open source

DOI: 10.1097/crd.0000000000001483
Published: 2026-09-29
Container: Cardiology in Review
Publisher: Ovid Technologies (Wolters Kluwer Health)
Open access: unknown

Credibility signals

uncertain Score 64/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

supportingDOI registered: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
supportingDOI resolves: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredOpen access status: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
supportingMetadata completeness: All 6 scored descriptive metadata groups are present. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1097/crd.0000000000001483,
  title = {Efficacy and Safety of Sodium-Glucose Cotransporter-2 Inhibitors for Heart Failure in Children and Adolescents: A Single-Arm and Pairwise Systematic Review and Meta-Analysis with GRADE Assessment of the Evidence},
  author = {Leen Adel Aldossary and Raghad Mamdouh Alanazi and Rana Motlk Almutairi and Tayba Abdulrahman Mugibel and Karen Deaa Ghanam and Robaiya Awadh Robaiya Ben-obaidellah and Khloud Awadh Mohammed and Asrar Abdulkarim Alharbi and Joudi Ali Almahabi and Rawan Abdullah Saad Alzahrani and Hala Salim Abu-Qasem and Mohamed Hamouda Elkasaby and Omer A. Algonaid and William H. Frishman and Wilbert S. Aronow},
  year = {2026},
  journal = {Cardiology in Review},
  doi = {10.1097/crd.0000000000001483},
  url = {https://doi.org/10.1097/crd.0000000000001483}
}

RIS

TY  - JOUR
TI  - Efficacy and Safety of Sodium-Glucose Cotransporter-2 Inhibitors for Heart Failure in Children and Adolescents: A Single-Arm and Pairwise Systematic Review and Meta-Analysis with GRADE Assessment of the Evidence
AU  - Leen Adel Aldossary
AU  - Raghad Mamdouh Alanazi
AU  - Rana Motlk Almutairi
AU  - Tayba Abdulrahman Mugibel
AU  - Karen Deaa Ghanam
AU  - Robaiya Awadh Robaiya Ben-obaidellah
AU  - Khloud Awadh Mohammed
AU  - Asrar Abdulkarim Alharbi
AU  - Joudi Ali Almahabi
AU  - Rawan Abdullah Saad Alzahrani
AU  - Hala Salim Abu-Qasem
AU  - Mohamed Hamouda Elkasaby
AU  - Omer A. Algonaid
AU  - William H. Frishman
AU  - Wilbert S. Aronow
PY  - 2026
JO  - Cardiology in Review
DO  - 10.1097/crd.0000000000001483
UR  - https://doi.org/10.1097/crd.0000000000001483
ER  -

APA

Aldossary, L. A., Alanazi, R. M., Almutairi, R. M., Mugibel, T. A., Ghanam, K. D., Ben-obaidellah, R. A. R., Mohammed, K. A., Alharbi, A. A., Almahabi, J. A., Alzahrani, R. A. S., Abu-Qasem, H. S., Elkasaby, M. H., Algonaid, O. A., Frishman, W. H., & Aronow, W. S. (2026). Efficacy and Safety of Sodium-Glucose Cotransporter-2 Inhibitors for Heart Failure in Children and Adolescents: A Single-Arm and Pairwise Systematic Review and Meta-Analysis with GRADE Assessment of the Evidence. Cardiology in Review. https://doi.org/10.1097/crd.0000000000001483

Source records

crossref · retrieved 2026-11-10T17:59:52.027Z