Depression severity and efficacy outcomes: post hoc analyses from a phase 3 trial of esmethadone for the adjunctive treatment of major depressive disorder with inadequate response to standard antidepressants

Clotilde Guidetti, George I. Papakostas, Steven Stahl, Luca Pani, Sara De Martin, Andrea Mattarei, Stefano Comai, Cornelia Kröger, Paggard Champasa, Charles W. Gorodetzky, Frank J. Vocci, Thomas R. Kosten, David Bushnell, Martin Kappler, Franco Folli, Charles E. Inturrisi, Marco Pappagallo, Paolo L. Manfredi, Maurizio Fava

Open source

DOI
10.1097/yic.0000000000000618
Published
2026-02-17
Container
International Clinical Psychopharmacology
Publisher
Ovid Technologies (Wolters Kluwer Health)
Open access
unknown

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BibTeX

@article{allodium:10.1097/yic.0000000000000618,
  title = {Depression severity and efficacy outcomes: post hoc analyses from a phase 3 trial of esmethadone for the adjunctive treatment of major depressive disorder with inadequate response to standard antidepressants},
  author = {Clotilde Guidetti and George I. Papakostas and Steven Stahl and Luca Pani and Sara De Martin and Andrea Mattarei and Stefano Comai and Cornelia Kröger and Paggard Champasa and Charles W. Gorodetzky and Frank J. Vocci and Thomas R. Kosten and David Bushnell and Martin Kappler and Franco Folli and Charles E. Inturrisi and Marco Pappagallo and Paolo L. Manfredi and Maurizio Fava},
  year = {2026},
  journal = {International Clinical Psychopharmacology},
  doi = {10.1097/yic.0000000000000618},
  url = {https://doi.org/10.1097/yic.0000000000000618}
}

RIS

TY  - JOUR
TI  - Depression severity and efficacy outcomes: post hoc analyses from a phase 3 trial of esmethadone for the adjunctive treatment of major depressive disorder with inadequate response to standard antidepressants
AU  - Clotilde Guidetti
AU  - George I. Papakostas
AU  - Steven Stahl
AU  - Luca Pani
AU  - Sara De Martin
AU  - Andrea Mattarei
AU  - Stefano Comai
AU  - Cornelia Kröger
AU  - Paggard Champasa
AU  - Charles W. Gorodetzky
AU  - Frank J. Vocci
AU  - Thomas R. Kosten
AU  - David Bushnell
AU  - Martin Kappler
AU  - Franco Folli
AU  - Charles E. Inturrisi
AU  - Marco Pappagallo
AU  - Paolo L. Manfredi
AU  - Maurizio Fava
PY  - 2026
JO  - International Clinical Psychopharmacology
DO  - 10.1097/yic.0000000000000618
UR  - https://doi.org/10.1097/yic.0000000000000618
ER  - 

APA

Guidetti, C., Papakostas, G. I., Stahl, S., Pani, L., Martin, S. D., Mattarei, A., Comai, S., Kröger, C., Champasa, P., Gorodetzky, C. W., Vocci, F. J., Kosten, T. R., Bushnell, D., Kappler, M., Folli, F., Inturrisi, C. E., Pappagallo, M., Manfredi, P. L., & Fava, M. (2026). Depression severity and efficacy outcomes: post hoc analyses from a phase 3 trial of esmethadone for the adjunctive treatment of major depressive disorder with inadequate response to standard antidepressants. International Clinical Psychopharmacology. https://doi.org/10.1097/yic.0000000000000618

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