Stratifying Lung Adenocarcinoma Risk with Multi-ancestry Polygenic Risk Scores in East Asian Never-Smokers

Batel Blechter, Xiaoyu Wang, Juncheng Dai, Christiana Karsonaki, Jianxin Shi, Kouya Shiraishi, Jiyeon Choi, Keitaro Matsuo, Tzu-Yu Chen, Rayjean J Hung, Kexin Chen, Xiao-Ou Shu, Young Tae Kim, Parichoy Pal Choudhury, Jacob Williams, Maria Teresa Landi, Dongxin Lin, Wei Zheng, Zhihua Yin, Baosen Zhou, Jiucun Wang, Wei Jie Seow, Lei Song, I-Shou Chang, Wei Hu, Li-Hsin Chien, Qiuyin Cai, Yun-Chul Hong, Hee Nam Kim, Yi-Long Wu, Maria Pik Wong, Brian Douglas Richardson, Shilan Li, Tongwu Zhang, Charles Breeze, Zhaoming Wang, Bryan A Bassig, Jin Hee Kim, Demetrius Albanes, Jason YY Wong, Min-Ho Shin, Lap Ping Chung, Yang Yang, Hong Zheng, Hongji Dai, Yasushi Yatabe, Xu-Chao Zhang, Young-Chul Kim, Neil E Caporaso, Jiang Chang, James Chung Man Ho, Yataro Daigo, Yukihide Momozawa, Yoichiro Kamatani, Masashi Kobayashi, Kenichi Okubo, Takayuki Honda, H Dean Hosgood, Hideo Kunitoh, Shun-ichi Watanabe, Yohei Miyagi, Shingo Matsumoto, Hidehito Horinouchi, Masahiro Tsuboi, Ryuji Hamamoto, Koichi Goto, Atsushi Takahashi, Akiteru Goto, Yoshihiro Minamiya, Megumi Hara, Yuichiro Nishida, Kenji Takeuchi, Kenji Wakai, Koichi Matsuda, Yoshinori Murakami, Kimihiro Shimizu, Hiroyuki Suzuki, Motonobu Saito, Yoichi Ohtaki, Kazumi Tanaka, Tangchun Wu, Fusheng Wei, Mitchell J Machiela, Yeul Hong Kim, In-Jae Oh, Victor Ho Fun Lee, Gee-Chen Chang, Kuan-Yu Chen, Wu-Chou Su, Yuh-Min Chen, Adeline Seow, Jae Yong Park, Sun-Seog Kweon, Yu-Tang Gao, Jianjun Liu, Ann G Schwartz, Richard Houlston, Ivan P Gorlov, Xifeng Wu, Ping Yang, Stephen Lam, Adonina Tardon, Chu Chen, Stig E Bojesen, Mattias Johansson, Angela Risch, Heike Bickeböller, Bu-Tian Ji, H-Erich Wichmann, David C Christiani, Gad Rennert, Susanne M Arnold, Paul Brennan, James McKay, John K Field, Michael P.A. Davies, Sanjay S Shete, Loïc Le Marchand, Geoffrey Liu, Angeline S Andrew, Lambertus A Kiemeney, Shan Zienolddiny-Narui, Kjell Grankvist, Angela Cox, Fiona Taylor, Jian-Min Yuan, Philip Lazarus, Matthew B Schabath, Melinda C Aldrich, Hyo-Sung Jeon, Shih Sheng Jiang, Chung-Hsing Chen, Chin-Fu Hsiao, Zhibin Hu, Laura Burdett, Meredith Yeager, Amy Hutchinson, Belynda Hicks, Jia Liu, Sonja I Berndt, Wei Wu, Junwen Wang, Yuqing Li, Jin Eun Choi, Kyong Hwa Park, Sook Whan Sung, Chang Hyun Kang, Wen-Chang Wang, Jun Xu, Peng Guan, Wen Tan, Chong-Jen Yu, Gong Yang, Alan Dart Loon Sihoe, Yi Young Choi, In Kyu Park, Hsiao-Han Hung, Roel C.H. Vermeulen, Iona Cheng, Junjie Wu, Fang-Yu Tsai, John K.C. Chan, Jihua Li, Hsien-Chih Lin, Jie Liu, Bao Song, Norie Sawada, Taiki Yamaji, Kathleen Wyatt, Hongxia Ma, Meng Zhu, Yifan Wang, Tianchen Qi, Xuelian Li, Yangwu Ren, Ann Chao, Motoki Iwasaki, Junjie Zhu, Guoping Wu, Chih-Yi Chen, Chien-Jen Chen, Pan-Chyr Yang, Victoria L. Stevens, Joseph F. Fraumeni, Kuang Lin, Robin G Walters, Zhengming Chen, Nilanjan Chatterjee, Olga Y Gorlova, Christopher I Amos, Hongbing Shen, Chao Agnes Hsiung, Stephen J Chanock, Nathaniel Rothman, Takashi Kohno, Qing Lan, Haoyu Zhang

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DOI
10.1101/2024.06.26.24309127
Published
2024-06-27
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openRxiv
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BibTeX

@article{allodium:10.1101/2024.06.26.24309127,
  title = {Stratifying Lung Adenocarcinoma Risk with Multi-ancestry Polygenic Risk Scores in East Asian Never-Smokers},
  author = {Batel Blechter and Xiaoyu Wang and Juncheng Dai and Christiana Karsonaki and Jianxin Shi and Kouya Shiraishi and Jiyeon Choi and Keitaro Matsuo and Tzu-Yu Chen and Rayjean J Hung and Kexin Chen and Xiao-Ou Shu and Young Tae Kim and Parichoy Pal Choudhury and Jacob Williams and Maria Teresa Landi and Dongxin Lin and Wei Zheng and Zhihua Yin and Baosen Zhou and Jiucun Wang and Wei Jie Seow and Lei Song and I-Shou Chang and Wei Hu and Li-Hsin Chien and Qiuyin Cai and Yun-Chul Hong and Hee Nam Kim and Yi-Long Wu and Maria Pik Wong and Brian Douglas Richardson and Shilan Li and Tongwu Zhang and Charles Breeze and Zhaoming Wang and Bryan A Bassig and Jin Hee Kim and Demetrius Albanes and Jason YY Wong and Min-Ho Shin and Lap Ping Chung and Yang Yang and Hong Zheng and Hongji Dai and Yasushi Yatabe and Xu-Chao Zhang and Young-Chul Kim and Neil E Caporaso and Jiang Chang and James Chung Man Ho and Yataro Daigo and Yukihide Momozawa and Yoichiro Kamatani and Masashi Kobayashi and Kenichi Okubo and Takayuki Honda and H Dean Hosgood and Hideo Kunitoh and Shun-ichi Watanabe and Yohei Miyagi and Shingo Matsumoto and Hidehito Horinouchi and Masahiro Tsuboi and Ryuji Hamamoto and Koichi Goto and Atsushi Takahashi and Akiteru Goto and Yoshihiro Minamiya and Megumi Hara and Yuichiro Nishida and Kenji Takeuchi and Kenji Wakai and Koichi Matsuda and Yoshinori Murakami and Kimihiro Shimizu and Hiroyuki Suzuki and Motonobu Saito and Yoichi Ohtaki and Kazumi Tanaka and Tangchun Wu and Fusheng Wei and Mitchell J Machiela and Yeul Hong Kim and In-Jae Oh and Victor Ho Fun Lee and Gee-Chen Chang and Kuan-Yu Chen and Wu-Chou Su and Yuh-Min Chen and Adeline Seow and Jae Yong Park and Sun-Seog Kweon and Yu-Tang Gao and Jianjun Liu and Ann G Schwartz and Richard Houlston and Ivan P Gorlov and Xifeng Wu and Ping Yang and Stephen Lam and Adonina Tardon and Chu Chen and Stig E Bojesen and Mattias Johansson and Angela Risch and Heike Bickeböller and Bu-Tian Ji and H-Erich Wichmann and David C Christiani and Gad Rennert and Susanne M Arnold and Paul Brennan and James McKay and John K Field and Michael P.A. Davies and Sanjay S Shete and Loïc Le Marchand and Geoffrey Liu and Angeline S Andrew and Lambertus A Kiemeney and Shan Zienolddiny-Narui and Kjell Grankvist and Angela Cox and Fiona Taylor and Jian-Min Yuan and Philip Lazarus and Matthew B Schabath and Melinda C Aldrich and Hyo-Sung Jeon and Shih Sheng Jiang and Chung-Hsing Chen and Chin-Fu Hsiao and Zhibin Hu and Laura Burdett and Meredith Yeager and Amy Hutchinson and Belynda Hicks and Jia Liu and Sonja I Berndt and Wei Wu and Junwen Wang and Yuqing Li and Jin Eun Choi and Kyong Hwa Park and Sook Whan Sung and Chang Hyun Kang and Wen-Chang Wang and Jun Xu and Peng Guan and Wen Tan and Chong-Jen Yu and Gong Yang and Alan Dart Loon Sihoe and Yi Young Choi and In Kyu Park and Hsiao-Han Hung and Roel C.H. Vermeulen and Iona Cheng and Junjie Wu and Fang-Yu Tsai and John K.C. Chan and Jihua Li and Hsien-Chih Lin and Jie Liu and Bao Song and Norie Sawada and Taiki Yamaji and Kathleen Wyatt and Hongxia Ma and Meng Zhu and Yifan Wang and Tianchen Qi and Xuelian Li and Yangwu Ren and Ann Chao and Motoki Iwasaki and Junjie Zhu and Guoping Wu and Chih-Yi Chen and Chien-Jen Chen and Pan-Chyr Yang and Victoria L. Stevens and Joseph F. Fraumeni and Kuang Lin and Robin G Walters and Zhengming Chen and Nilanjan Chatterjee and Olga Y Gorlova and Christopher I Amos and Hongbing Shen and Chao Agnes Hsiung and Stephen J Chanock and Nathaniel Rothman and Takashi Kohno and Qing Lan and Haoyu Zhang},
  year = {2024},
  doi = {10.1101/2024.06.26.24309127},
  url = {https://doi.org/10.1101/2024.06.26.24309127}
}

RIS

TY  - JOUR
TI  - Stratifying Lung Adenocarcinoma Risk with Multi-ancestry Polygenic Risk Scores in East Asian Never-Smokers
AU  - Batel Blechter
AU  - Xiaoyu Wang
AU  - Juncheng Dai
AU  - Christiana Karsonaki
AU  - Jianxin Shi
AU  - Kouya Shiraishi
AU  - Jiyeon Choi
AU  - Keitaro Matsuo
AU  - Tzu-Yu Chen
AU  - Rayjean J Hung
AU  - Kexin Chen
AU  - Xiao-Ou Shu
AU  - Young Tae Kim
AU  - Parichoy Pal Choudhury
AU  - Jacob Williams
AU  - Maria Teresa Landi
AU  - Dongxin Lin
AU  - Wei Zheng
AU  - Zhihua Yin
AU  - Baosen Zhou
AU  - Jiucun Wang
AU  - Wei Jie Seow
AU  - Lei Song
AU  - I-Shou Chang
AU  - Wei Hu
AU  - Li-Hsin Chien
AU  - Qiuyin Cai
AU  - Yun-Chul Hong
AU  - Hee Nam Kim
AU  - Yi-Long Wu
AU  - Maria Pik Wong
AU  - Brian Douglas Richardson
AU  - Shilan Li
AU  - Tongwu Zhang
AU  - Charles Breeze
AU  - Zhaoming Wang
AU  - Bryan A Bassig
AU  - Jin Hee Kim
AU  - Demetrius Albanes
AU  - Jason YY Wong
AU  - Min-Ho Shin
AU  - Lap Ping Chung
AU  - Yang Yang
AU  - Hong Zheng
AU  - Hongji Dai
AU  - Yasushi Yatabe
AU  - Xu-Chao Zhang
AU  - Young-Chul Kim
AU  - Neil E Caporaso
AU  - Jiang Chang
AU  - James Chung Man Ho
AU  - Yataro Daigo
AU  - Yukihide Momozawa
AU  - Yoichiro Kamatani
AU  - Masashi Kobayashi
AU  - Kenichi Okubo
AU  - Takayuki Honda
AU  - H Dean Hosgood
AU  - Hideo Kunitoh
AU  - Shun-ichi Watanabe
AU  - Yohei Miyagi
AU  - Shingo Matsumoto
AU  - Hidehito Horinouchi
AU  - Masahiro Tsuboi
AU  - Ryuji Hamamoto
AU  - Koichi Goto
AU  - Atsushi Takahashi
AU  - Akiteru Goto
AU  - Yoshihiro Minamiya
AU  - Megumi Hara
AU  - Yuichiro Nishida
AU  - Kenji Takeuchi
AU  - Kenji Wakai
AU  - Koichi Matsuda
AU  - Yoshinori Murakami
AU  - Kimihiro Shimizu
AU  - Hiroyuki Suzuki
AU  - Motonobu Saito
AU  - Yoichi Ohtaki
AU  - Kazumi Tanaka
AU  - Tangchun Wu
AU  - Fusheng Wei
AU  - Mitchell J Machiela
AU  - Yeul Hong Kim
AU  - In-Jae Oh
AU  - Victor Ho Fun Lee
AU  - Gee-Chen Chang
AU  - Kuan-Yu Chen
AU  - Wu-Chou Su
AU  - Yuh-Min Chen
AU  - Adeline Seow
AU  - Jae Yong Park
AU  - Sun-Seog Kweon
AU  - Yu-Tang Gao
AU  - Jianjun Liu
AU  - Ann G Schwartz
AU  - Richard Houlston
AU  - Ivan P Gorlov
AU  - Xifeng Wu
AU  - Ping Yang
AU  - Stephen Lam
AU  - Adonina Tardon
AU  - Chu Chen
AU  - Stig E Bojesen
AU  - Mattias Johansson
AU  - Angela Risch
AU  - Heike Bickeböller
AU  - Bu-Tian Ji
AU  - H-Erich Wichmann
AU  - David C Christiani
AU  - Gad Rennert
AU  - Susanne M Arnold
AU  - Paul Brennan
AU  - James McKay
AU  - John K Field
AU  - Michael P.A. Davies
AU  - Sanjay S Shete
AU  - Loïc Le Marchand
AU  - Geoffrey Liu
AU  - Angeline S Andrew
AU  - Lambertus A Kiemeney
AU  - Shan Zienolddiny-Narui
AU  - Kjell Grankvist
AU  - Angela Cox
AU  - Fiona Taylor
AU  - Jian-Min Yuan
AU  - Philip Lazarus
AU  - Matthew B Schabath
AU  - Melinda C Aldrich
AU  - Hyo-Sung Jeon
AU  - Shih Sheng Jiang
AU  - Chung-Hsing Chen
AU  - Chin-Fu Hsiao
AU  - Zhibin Hu
AU  - Laura Burdett
AU  - Meredith Yeager
AU  - Amy Hutchinson
AU  - Belynda Hicks
AU  - Jia Liu
AU  - Sonja I Berndt
AU  - Wei Wu
AU  - Junwen Wang
AU  - Yuqing Li
AU  - Jin Eun Choi
AU  - Kyong Hwa Park
AU  - Sook Whan Sung
AU  - Chang Hyun Kang
AU  - Wen-Chang Wang
AU  - Jun Xu
AU  - Peng Guan
AU  - Wen Tan
AU  - Chong-Jen Yu
AU  - Gong Yang
AU  - Alan Dart Loon Sihoe
AU  - Yi Young Choi
AU  - In Kyu Park
AU  - Hsiao-Han Hung
AU  - Roel C.H. Vermeulen
AU  - Iona Cheng
AU  - Junjie Wu
AU  - Fang-Yu Tsai
AU  - John K.C. Chan
AU  - Jihua Li
AU  - Hsien-Chih Lin
AU  - Jie Liu
AU  - Bao Song
AU  - Norie Sawada
AU  - Taiki Yamaji
AU  - Kathleen Wyatt
AU  - Hongxia Ma
AU  - Meng Zhu
AU  - Yifan Wang
AU  - Tianchen Qi
AU  - Xuelian Li
AU  - Yangwu Ren
AU  - Ann Chao
AU  - Motoki Iwasaki
AU  - Junjie Zhu
AU  - Guoping Wu
AU  - Chih-Yi Chen
AU  - Chien-Jen Chen
AU  - Pan-Chyr Yang
AU  - Victoria L. Stevens
AU  - Joseph F. Fraumeni
AU  - Kuang Lin
AU  - Robin G Walters
AU  - Zhengming Chen
AU  - Nilanjan Chatterjee
AU  - Olga Y Gorlova
AU  - Christopher I Amos
AU  - Hongbing Shen
AU  - Chao Agnes Hsiung
AU  - Stephen J Chanock
AU  - Nathaniel Rothman
AU  - Takashi Kohno
AU  - Qing Lan
AU  - Haoyu Zhang
PY  - 2024
DO  - 10.1101/2024.06.26.24309127
UR  - https://doi.org/10.1101/2024.06.26.24309127
ER  -

APA

Blechter, B., Wang, X., Dai, J., Karsonaki, C., Shi, J., Shiraishi, K., Choi, J., Matsuo, K., Chen, T., Hung, R. J., Chen, K., Shu, X., Kim, Y. T., Choudhury, P. P., Williams, J., Landi, M. T., Lin, D., Zheng, W., Yin, Z., Zhou, B., Wang, J., Seow, W. J., Song, L., Chang, I., Hu, W., Chien, L., Cai, Q., Hong, Y., Kim, H. N., Wu, Y., Wong, M. P., Richardson, B. D., Li, S., Zhang, T., Breeze, C., Wang, Z., Bassig, B. A., Kim, J. H., Albanes, D., Wong, J. Y., Shin, M., Chung, L. P., Yang, Y., Zheng, H., Dai, H., Yatabe, Y., Zhang, X., Kim, Y., Caporaso, N. E., Chang, J., Ho, J. C. M., Daigo, Y., Momozawa, Y., Kamatani, Y., Kobayashi, M., Okubo, K., Honda, T., Hosgood, H. D., Kunitoh, H., Watanabe, S., Miyagi, Y., Matsumoto, S., Horinouchi, H., Tsuboi, M., Hamamoto, R., Goto, K., Takahashi, A., Goto, A., Minamiya, Y., Hara, M., Nishida, Y., Takeuchi, K., Wakai, K., Matsuda, K., Murakami, Y., Shimizu, K., Suzuki, H., Saito, M., Ohtaki, Y., Tanaka, K., Wu, T., Wei, F., Machiela, M. J., Kim, Y. H., Oh, I., Lee, V. H. F., Chang, G., Chen, K., Su, W., Chen, Y., Seow, A., Park, J. Y., Kweon, S., Gao, Y., Liu, J., Schwartz, A. G., Houlston, R., Gorlov, I. P., Wu, X., Yang, P., Lam, S., Tardon, A., Chen, C., Bojesen, S. E., Johansson, M., Risch, A., Bickeböller, H., Ji, B., Wichmann, H., Christiani, D. C., Rennert, G., Arnold, S. M., Brennan, P., McKay, J., Field, J. K., Davies, M. P., Shete, S. S., Marchand, L. L., Liu, G., Andrew, A. S., Kiemeney, L. A., Zienolddiny-Narui, S., Grankvist, K., Cox, A., Taylor, F., Yuan, J., Lazarus, P., Schabath, M. B., Aldrich, M. C., Jeon, H., Jiang, S. S., Chen, C., Hsiao, C., Hu, Z., Burdett, L., Yeager, M., Hutchinson, A., Hicks, B., Liu, J., Berndt, S. I., Wu, W., Wang, J., Li, Y., Choi, J. E., Park, K. H., Sung, S. W., Kang, C. H., Wang, W., Xu, J., Guan, P., Tan, W., Yu, C., Yang, G., Sihoe, A. D. L., Choi, Y. Y., Park, I. K., Hung, H., Vermeulen, R. C., Cheng, I., Wu, J., Tsai, F., Chan, J. K., Li, J., Lin, H., Liu, J., Song, B., Sawada, N., Yamaji, T., Wyatt, K., Ma, H., Zhu, M., Wang, Y., Qi, T., Li, X., Ren, Y., Chao, A., Iwasaki, M., Zhu, J., Wu, G., Chen, C., Chen, C., Yang, P., Stevens, V. L., Fraumeni, J. F., Lin, K., Walters, R. G., Chen, Z., Chatterjee, N., Gorlova, O. Y., Amos, C. I., Shen, H., Hsiung, C. A., Chanock, S. J., Rothman, N., Kohno, T., Lan, Q., & Zhang, H. (2024). Stratifying Lung Adenocarcinoma Risk with Multi-ancestry Polygenic Risk Scores in East Asian Never-Smokers. https://doi.org/10.1101/2024.06.26.24309127

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