Safety and efficacy of long-term gantenerumab treatment in dominantly inherited Alzheimer’s disease: an open label extension of the phase 2/3 multicentre, randomised, double-blind, placebo-controlled platform DIAN-TU Trial

Randall J. Bateman, Yan Li, Eric M. McDade, Jorge J. Llibre-Guerra, David B. Clifford, Alireza Atri, Susan L. Mills, Anna M. Santacruz, Guoqiao Wang, Charlene Supnet, Tammie L. S. Benzinger, Brian A. Gordon, Laura Ibanez, Gregory Klein, Monika Baudler, Rachelle S. Doody, Paul Delmar, Geoffrey A. Kerchner, Tobias Bittner, Jakub Wojtowicz, Azad Bonni, Paulo Fontoura, Carsten Hofmann, Luka Kulic, Jason Hassenstab, Andrew J. Aschenbrenner, Richard J. Perrin, Carlos Cruchaga, Alan E. Renton, Chengjie Xiong, Alison A. Goate, John C. Morris, David M. Holtzman, B. Joy Snider, Catherine Mummery, William S. Brooks, David Wallon, Sarah B. Berman, Erik Roberson, Colin L. Masters, Douglas R. Galasko, Suman Jayadev, Rachel Sanchez-Valle, Jeremie Pariente, Justin Kinsella, Christopher H. van Dyck, Serge Gauthier, Ging-Yuek Robin Hsiung, Mario Masellis, Bruno Dubois, Lawrence S. Honig, Clifford R. Jack, Alisha Daniels, David Aguillón, Ricardo Allegri, Jasmeer Chhatwal, Gregory Day, Nick Fox, Edward Huey, Takeshi Ikeuchi, Mathias Jucker, Jae-Hong Lee, Allan I. Levey, Johannes Levin, Francisco Lopera, JeeHoon Roh, Pedro Rosa-Neto, Peter R. Schofield, Unknown

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DOI: 10.1101/2024.10.29.24316289
Published: 2024-11-06
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Publisher: openRxiv
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Cite this work

BibTeX

@article{allodium:10.1101/2024.10.29.24316289,
title = {Safety and efficacy of long-term gantenerumab treatment in dominantly inherited Alzheimer’s disease: an open label extension of the phase 2/3 multicentre, randomised, double-blind, placebo-controlled platform DIAN-TU Trial},
author = {Randall J. Bateman and Yan Li and Eric M. McDade and Jorge J. Llibre-Guerra and David B. Clifford and Alireza Atri and Susan L. Mills and Anna M. Santacruz and Guoqiao Wang and Charlene Supnet and Tammie L. S. Benzinger and Brian A. Gordon and Laura Ibanez and Gregory Klein and Monika Baudler and Rachelle S. Doody and Paul Delmar and Geoffrey A. Kerchner and Tobias Bittner and Jakub Wojtowicz and Azad Bonni and Paulo Fontoura and Carsten Hofmann and Luka Kulic and Jason Hassenstab and Andrew J. Aschenbrenner and Richard J. Perrin and Carlos Cruchaga and Alan E. Renton and Chengjie Xiong and Alison A. Goate and John C. Morris and David M. Holtzman and B. Joy Snider and Catherine Mummery and William S. Brooks and David Wallon and Sarah B. Berman and Erik Roberson and Colin L. Masters and Douglas R. Galasko and Suman Jayadev and Rachel Sanchez-Valle and Jeremie Pariente and Justin Kinsella and Christopher H. van Dyck and Serge Gauthier and Ging-Yuek Robin Hsiung and Mario Masellis and Bruno Dubois and Lawrence S. Honig and Clifford R. Jack and Alisha Daniels and David Aguillón and Ricardo Allegri and Jasmeer Chhatwal and Gregory Day and Nick Fox and Edward Huey and Takeshi Ikeuchi and Mathias Jucker and Jae-Hong Lee and Allan I. Levey and Johannes Levin and Francisco Lopera and JeeHoon Roh and Pedro Rosa-Neto and Peter R. Schofield and Unknown},
year = {2024},
doi = {10.1101/2024.10.29.24316289},
url = {https://doi.org/10.1101/2024.10.29.24316289}
}

RIS

TY  - JOUR
TI  - Safety and efficacy of long-term gantenerumab treatment in dominantly inherited Alzheimer’s disease: an open label extension of the phase 2/3 multicentre, randomised, double-blind, placebo-controlled platform DIAN-TU Trial
AU  - Randall J. Bateman
AU  - Yan Li
AU  - Eric M. McDade
AU  - Jorge J. Llibre-Guerra
AU  - David B. Clifford
AU  - Alireza Atri
AU  - Susan L. Mills
AU  - Anna M. Santacruz
AU  - Guoqiao Wang
AU  - Charlene Supnet
AU  - Tammie L. S. Benzinger
AU  - Brian A. Gordon
AU  - Laura Ibanez
AU  - Gregory Klein
AU  - Monika Baudler
AU  - Rachelle S. Doody
AU  - Paul Delmar
AU  - Geoffrey A. Kerchner
AU  - Tobias Bittner
AU  - Jakub Wojtowicz
AU  - Azad Bonni
AU  - Paulo Fontoura
AU  - Carsten Hofmann
AU  - Luka Kulic
AU  - Jason Hassenstab
AU  - Andrew J. Aschenbrenner
AU  - Richard J. Perrin
AU  - Carlos Cruchaga
AU  - Alan E. Renton
AU  - Chengjie Xiong
AU  - Alison A. Goate
AU  - John C. Morris
AU  - David M. Holtzman
AU  - B. Joy Snider
AU  - Catherine Mummery
AU  - William S. Brooks
AU  - David Wallon
AU  - Sarah B. Berman
AU  - Erik Roberson
AU  - Colin L. Masters
AU  - Douglas R. Galasko
AU  - Suman Jayadev
AU  - Rachel Sanchez-Valle
AU  - Jeremie Pariente
AU  - Justin Kinsella
AU  - Christopher H. van Dyck
AU  - Serge Gauthier
AU  - Ging-Yuek Robin Hsiung
AU  - Mario Masellis
AU  - Bruno Dubois
AU  - Lawrence S. Honig
AU  - Clifford R. Jack
AU  - Alisha Daniels
AU  - David Aguillón
AU  - Ricardo Allegri
AU  - Jasmeer Chhatwal
AU  - Gregory Day
AU  - Nick Fox
AU  - Edward Huey
AU  - Takeshi Ikeuchi
AU  - Mathias Jucker
AU  - Jae-Hong Lee
AU  - Allan I. Levey
AU  - Johannes Levin
AU  - Francisco Lopera
AU  - JeeHoon Roh
AU  - Pedro Rosa-Neto
AU  - Peter R. Schofield
AU  - Unknown
PY  - 2024
DO  - 10.1101/2024.10.29.24316289
UR  - https://doi.org/10.1101/2024.10.29.24316289
ER  -

APA

Bateman, R. J., Li, Y., McDade, E. M., Llibre-Guerra, J. J., Clifford, D. B., Atri, A., Mills, S. L., Santacruz, A. M., Wang, G., Supnet, C., Benzinger, T. L. S., Gordon, B. A., Ibanez, L., Klein, G., Baudler, M., Doody, R. S., Delmar, P., Kerchner, G. A., Bittner, T., Wojtowicz, J., Bonni, A., Fontoura, P., Hofmann, C., Kulic, L., Hassenstab, J., Aschenbrenner, A. J., Perrin, R. J., Cruchaga, C., Renton, A. E., Xiong, C., Goate, A. A., Morris, J. C., Holtzman, D. M., Snider, B. J., Mummery, C., Brooks, W. S., Wallon, D., Berman, S. B., Roberson, E., Masters, C. L., Galasko, D. R., Jayadev, S., Sanchez-Valle, R., Pariente, J., Kinsella, J., Dyck, C. H. V., Gauthier, S., Hsiung, G. R., Masellis, M., Dubois, B., Honig, L. S., Jack, C. R., Daniels, A., Aguillón, D., Allegri, R., Chhatwal, J., Day, G., Fox, N., Huey, E., Ikeuchi, T., Jucker, M., Lee, J., Levey, A. I., Levin, J., Lopera, F., Roh, J., Rosa-Neto, P., Schofield, P. R., & Unknown (2024). Safety and efficacy of long-term gantenerumab treatment in dominantly inherited Alzheimer’s disease: an open label extension of the phase 2/3 multicentre, randomised, double-blind, placebo-controlled platform DIAN-TU Trial. https://doi.org/10.1101/2024.10.29.24316289

Source records

crossref · retrieved 2026-09-26T02:25:11.482Z