The H3 <sup>K36M</sup> oncohistone inhibits NSD2 to activate a SETD2-dependent antiviral-like immune response in KRAS-driven lung cancer

Amy C. Gladstein, Carson D. Poltorack, Akino Mercy Charles Solomon, Sharan Venkatesh, Keren M. Adler, Maggie R. Robertson, Stephanie Stransky, Valerie M. Irizarry-Negron, Dain A. Ruiz, Nelson F. Freeburg, Simone Sidoli, Irfan A. Asangani, Sydney M. Shaffer, David M. Feldser

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DOI: 10.1101/2025.05.25.655971
Published: 2025-05-28
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Publisher: openRxiv
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BibTeX

@article{allodium:10.1101/2025.05.25.655971,
  title = {The H3
                  <sup>K36M</sup>
                  oncohistone inhibits NSD2 to activate a SETD2-dependent antiviral-like immune response in KRAS-driven lung cancer},
  author = {Amy C. Gladstein and Carson D. Poltorack and Akino Mercy Charles Solomon and Sharan Venkatesh and Keren M. Adler and Maggie R. Robertson and Stephanie Stransky and Valerie M. Irizarry-Negron and Dain A. Ruiz and Nelson F. Freeburg and Simone Sidoli and Irfan A. Asangani and Sydney M. Shaffer and David M. Feldser},
  year = {2025},
  doi = {10.1101/2025.05.25.655971},
  url = {https://doi.org/10.1101/2025.05.25.655971}
}

RIS

TY  - JOUR
TI  - The H3
                  <sup>K36M</sup>
                  oncohistone inhibits NSD2 to activate a SETD2-dependent antiviral-like immune response in KRAS-driven lung cancer
AU  - Amy C. Gladstein
AU  - Carson D. Poltorack
AU  - Akino Mercy Charles Solomon
AU  - Sharan Venkatesh
AU  - Keren M. Adler
AU  - Maggie R. Robertson
AU  - Stephanie Stransky
AU  - Valerie M. Irizarry-Negron
AU  - Dain A. Ruiz
AU  - Nelson F. Freeburg
AU  - Simone Sidoli
AU  - Irfan A. Asangani
AU  - Sydney M. Shaffer
AU  - David M. Feldser
PY  - 2025
DO  - 10.1101/2025.05.25.655971
UR  - https://doi.org/10.1101/2025.05.25.655971
ER  -

APA

Gladstein, A. C., Poltorack, C. D., Solomon, A. M. C., Venkatesh, S., Adler, K. M., Robertson, M. R., Stransky, S., Irizarry-Negron, V. M., Ruiz, D. A., Freeburg, N. F., Sidoli, S., Asangani, I. A., Shaffer, S. M., & Feldser, D. M. (2025). The H3 <sup>K36M</sup> oncohistone inhibits NSD2 to activate a SETD2-dependent antiviral-like immune response in KRAS-driven lung cancer. https://doi.org/10.1101/2025.05.25.655971

Source records

crossref · retrieved 2026-09-27T09:53:44.539Z