A phase 1 randomized, placebo-controlled trial of a combination typhoid and non-typhoidal Salmonella polysaccharide conjugate vaccine.

Chen WH, Barnes RS, Sikorski MJ, Datar R, Sukhavasi R, Liang Y, Rapaka RR, Pasetti MF, Sztein MB, Wahid R, Tennant SM, Simon R, Baliban SM, Galen JE, Lees A, Bernshtein B, Alter G, Ella R, Mohan K, Naidu MG, Rao DY, Ella KM, Levine MM

Open source

DOI: 10.1101/2025.09.15.25335795
Published: 2025 Sep 18
Container: medRxiv : the preprint server for health sciences
Publisher: Not recorded
Open access: yes

Credibility signals

limited evidence Score 45/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

cautionDOI registered: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
cautionDOI resolves: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
supportingOpen access status: Normalized open-access status: open. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1101/2025.09.15.25335795,
  title = {A phase 1 randomized, placebo-controlled trial of a combination typhoid and non-typhoidal Salmonella polysaccharide conjugate vaccine.},
  author = {Chen WH and Barnes RS and Sikorski MJ and Datar R and Sukhavasi R and Liang Y and Rapaka RR and Pasetti MF and Sztein MB and Wahid R and Tennant SM and Simon R and Baliban SM and Galen JE and Lees A and Bernshtein B and Alter G and Ella R and Mohan K and Naidu MG and Rao DY and Ella KM and Levine MM},
  year = {2025},
  journal = {medRxiv : the preprint server for health sciences},
  doi = {10.1101/2025.09.15.25335795},
  url = {https://doi.org/10.1101/2025.09.15.25335795}
}

RIS

TY  - JOUR
TI  - A phase 1 randomized, placebo-controlled trial of a combination typhoid and non-typhoidal Salmonella polysaccharide conjugate vaccine.
AU  - Chen WH
AU  - Barnes RS
AU  - Sikorski MJ
AU  - Datar R
AU  - Sukhavasi R
AU  - Liang Y
AU  - Rapaka RR
AU  - Pasetti MF
AU  - Sztein MB
AU  - Wahid R
AU  - Tennant SM
AU  - Simon R
AU  - Baliban SM
AU  - Galen JE
AU  - Lees A
AU  - Bernshtein B
AU  - Alter G
AU  - Ella R
AU  - Mohan K
AU  - Naidu MG
AU  - Rao DY
AU  - Ella KM
AU  - Levine MM
PY  - 2025
JO  - medRxiv : the preprint server for health sciences
DO  - 10.1101/2025.09.15.25335795
UR  - https://doi.org/10.1101/2025.09.15.25335795
ER  -

APA

WH, C., RS, B., MJ, S., R, D., R, S., Y, L., RR, R., MF, P., MB, S., R, W., SM, T., R, S., SM, B., JE, G., A, L., B, B., G, A., R, E., K, M., MG, N., DY, R., KM, E., & MM, L. (2025). A phase 1 randomized, placebo-controlled trial of a combination typhoid and non-typhoidal Salmonella polysaccharide conjugate vaccine.. medRxiv : the preprint server for health sciences. https://doi.org/10.1101/2025.09.15.25335795

Source records

pubmed · retrieved 2026-09-26T15:14:40.612Z
europe-pmc · retrieved 2026-09-26T15:14:40.604Z