Robust CD4(+) CAR T cell Expansion Is Associated with Non-ICANS Neurotoxicities Following Ciltacabtagene Autoleucel.

Jurgens EM, Mitra S, Herrera K, Nemirovsky D, Bready B, Derkach A, Hosszu K, McAvoy D, Firestone RS, Rajeeve S, Lesokhin AM, Korde N, Tan CR, Hashmi H, Hassoun H, Maclachlan K, Shah UA, Hultcrantz M, Merz M, Maura F, Giralt SA, Shah G, Landau HJ, Scordo M, Santomasso BD, Park J, Leslie C, Usmani SZ, Perica K, Mailankody S

Open source

DOI: 10.1101/2025.10.28.25338924
Published: 2025 Oct 30
Container: medRxiv : the preprint server for health sciences
Publisher: Not recorded
Open access: yes

Credibility signals

limited evidence Score 45/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

cautionDOI registered: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
cautionDOI resolves: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
supportingOpen access status: Normalized open-access status: open. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1101/2025.10.28.25338924,
  title = {Robust CD4(+) CAR T cell Expansion Is Associated with Non-ICANS Neurotoxicities Following Ciltacabtagene Autoleucel.},
  author = {Jurgens EM and Mitra S and Herrera K and Nemirovsky D and Bready B and Derkach A and Hosszu K and McAvoy D and Firestone RS and Rajeeve S and Lesokhin AM and Korde N and Tan CR and Hashmi H and Hassoun H and Maclachlan K and Shah UA and Hultcrantz M and Merz M and Maura F and Giralt SA and Shah G and Landau HJ and Scordo M and Santomasso BD and Park J and Leslie C and Usmani SZ and Perica K and Mailankody S},
  year = {2025},
  journal = {medRxiv : the preprint server for health sciences},
  doi = {10.1101/2025.10.28.25338924},
  url = {https://doi.org/10.1101/2025.10.28.25338924}
}

RIS

TY  - JOUR
TI  - Robust CD4(+) CAR T cell Expansion Is Associated with Non-ICANS Neurotoxicities Following Ciltacabtagene Autoleucel.
AU  - Jurgens EM
AU  - Mitra S
AU  - Herrera K
AU  - Nemirovsky D
AU  - Bready B
AU  - Derkach A
AU  - Hosszu K
AU  - McAvoy D
AU  - Firestone RS
AU  - Rajeeve S
AU  - Lesokhin AM
AU  - Korde N
AU  - Tan CR
AU  - Hashmi H
AU  - Hassoun H
AU  - Maclachlan K
AU  - Shah UA
AU  - Hultcrantz M
AU  - Merz M
AU  - Maura F
AU  - Giralt SA
AU  - Shah G
AU  - Landau HJ
AU  - Scordo M
AU  - Santomasso BD
AU  - Park J
AU  - Leslie C
AU  - Usmani SZ
AU  - Perica K
AU  - Mailankody S
PY  - 2025
JO  - medRxiv : the preprint server for health sciences
DO  - 10.1101/2025.10.28.25338924
UR  - https://doi.org/10.1101/2025.10.28.25338924
ER  -

APA

EM, J., S, M., K, H., D, N., B, B., A, D., K, H., D, M., RS, F., S, R., AM, L., N, K., CR, T., H, H., H, H., K, M., UA, S., M, H., M, M., F, M., SA, G., G, S., HJ, L., M, S., BD, S., J, P., C, L., SZ, U., K, P., & S, M. (2025). Robust CD4(+) CAR T cell Expansion Is Associated with Non-ICANS Neurotoxicities Following Ciltacabtagene Autoleucel.. medRxiv : the preprint server for health sciences. https://doi.org/10.1101/2025.10.28.25338924

Source records

pubmed · retrieved 2026-09-27T17:22:57.941Z