Charting the undiscovered metabolome with synthetic multiplexing implicates ibuprofen-carnitine in myotoxicity

Abubaker Patan, Shipei Xing, Vincent Charron-Lamoureux, Zhewen Hu, Victoria Deleray, Julius Agongo, Jasmine Zemlin, Harsha Gouda, Prajit Rajkumar, Yasin El Abiead, Aubreyana E. McMaugh, Hannah Heath, Helena Mannochio-Russo, Ipsita Mohanty, Laila Abolfathi, Ricardo Almada-Monter, Jia Yang, Carlynda Lee, Daniel Leanos, Noah Weimann, Wataru Tsuda, Sadie Giddings, Tammy Bui, Eric Ding, Kine Eide Kvitne, Haoqi Nina Zhao, Simone Zuffa, Paulo Wender Portal Gomes, Vivian Nguyen, Aileen Andrade, Maria A Pawlowski, Ashley C Ferland, Elisabeth Orozco, Wilhan Donizete Gonçalves Nunes, Andrés M. Caraballo-Rodríguez, Lurian Caetano David, Kathleen M. Giacomini, Adrian Jinich, Jeremy Carver, Nuno Bandeira, Mingxun Wang, Lindsey A. Burnett, Dionicio Siegel, Pieter C. Dorrestein

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DOI: 10.1101/2025.11.18.689170
Published: 2025-11-19
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Publisher: openRxiv
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Cite this work

BibTeX

@article{allodium:10.1101/2025.11.18.689170,
  title = {Charting the undiscovered metabolome with synthetic multiplexing implicates ibuprofen-carnitine in myotoxicity},
  author = {Abubaker Patan and Shipei Xing and Vincent Charron-Lamoureux and Zhewen Hu and Victoria Deleray and Julius Agongo and Jasmine Zemlin and Harsha Gouda and Prajit Rajkumar and Yasin El Abiead and Aubreyana E. McMaugh and Hannah Heath and Helena Mannochio-Russo and Ipsita Mohanty and Laila Abolfathi and Ricardo Almada-Monter and Jia Yang and Carlynda Lee and Daniel Leanos and Noah Weimann and Wataru Tsuda and Sadie Giddings and Tammy Bui and Eric Ding and Kine Eide Kvitne and Haoqi Nina Zhao and Simone Zuffa and Paulo Wender Portal Gomes and Vivian Nguyen and Aileen Andrade and Maria A Pawlowski and Ashley C Ferland and Elisabeth Orozco and Wilhan Donizete Gonçalves Nunes and Andrés M. Caraballo-Rodríguez and Lurian Caetano David and Kathleen M. Giacomini and Adrian Jinich and Jeremy Carver and Nuno Bandeira and Mingxun Wang and Lindsey A. Burnett and Dionicio Siegel and Pieter C. Dorrestein},
  year = {2025},
  doi = {10.1101/2025.11.18.689170},
  url = {https://doi.org/10.1101/2025.11.18.689170}
}

RIS

TY  - JOUR
TI  - Charting the undiscovered metabolome with synthetic multiplexing implicates ibuprofen-carnitine in myotoxicity
AU  - Abubaker Patan
AU  - Shipei Xing
AU  - Vincent Charron-Lamoureux
AU  - Zhewen Hu
AU  - Victoria Deleray
AU  - Julius Agongo
AU  - Jasmine Zemlin
AU  - Harsha Gouda
AU  - Prajit Rajkumar
AU  - Yasin El Abiead
AU  - Aubreyana E. McMaugh
AU  - Hannah Heath
AU  - Helena Mannochio-Russo
AU  - Ipsita Mohanty
AU  - Laila Abolfathi
AU  - Ricardo Almada-Monter
AU  - Jia Yang
AU  - Carlynda Lee
AU  - Daniel Leanos
AU  - Noah Weimann
AU  - Wataru Tsuda
AU  - Sadie Giddings
AU  - Tammy Bui
AU  - Eric Ding
AU  - Kine Eide Kvitne
AU  - Haoqi Nina Zhao
AU  - Simone Zuffa
AU  - Paulo Wender Portal Gomes
AU  - Vivian Nguyen
AU  - Aileen Andrade
AU  - Maria A Pawlowski
AU  - Ashley C Ferland
AU  - Elisabeth Orozco
AU  - Wilhan Donizete Gonçalves Nunes
AU  - Andrés M. Caraballo-Rodríguez
AU  - Lurian Caetano David
AU  - Kathleen M. Giacomini
AU  - Adrian Jinich
AU  - Jeremy Carver
AU  - Nuno Bandeira
AU  - Mingxun Wang
AU  - Lindsey A. Burnett
AU  - Dionicio Siegel
AU  - Pieter C. Dorrestein
PY  - 2025
DO  - 10.1101/2025.11.18.689170
UR  - https://doi.org/10.1101/2025.11.18.689170
ER  -

APA

Patan, A., Xing, S., Charron-Lamoureux, V., Hu, Z., Deleray, V., Agongo, J., Zemlin, J., Gouda, H., Rajkumar, P., Abiead, Y. E., McMaugh, A. E., Heath, H., Mannochio-Russo, H., Mohanty, I., Abolfathi, L., Almada-Monter, R., Yang, J., Lee, C., Leanos, D., Weimann, N., Tsuda, W., Giddings, S., Bui, T., Ding, E., Kvitne, K. E., Zhao, H. N., Zuffa, S., Gomes, P. W. P., Nguyen, V., Andrade, A., Pawlowski, M. A., Ferland, A. C., Orozco, E., Nunes, W. D. G., Caraballo-Rodríguez, A. M., David, L. C., Giacomini, K. M., Jinich, A., Carver, J., Bandeira, N., Wang, M., Burnett, L. A., Siegel, D., & Dorrestein, P. C. (2025). Charting the undiscovered metabolome with synthetic multiplexing implicates ibuprofen-carnitine in myotoxicity. https://doi.org/10.1101/2025.11.18.689170

Source records

crossref · retrieved 2026-09-25T10:42:25.074Z