Functional recovery of islet β cells in human type 2 diabetes: Transcriptome signatures unveil therapeutic approaches.

Suleiman M, Sawatani T, Tesi M, Yi X, Papadopoulou T, Rufer C, Lytrivi M, Bosi E, Burdet F, Fantuzzi F, De Luca C, Sebastiani G, Saponaro C, Pugliese LA, Del Guerra S, Pocai A, De Simone P, Ghinolfi D, Boggi U, Kessler C, Grieco GE, Fignani D, Kerr-Conte J, Pattou F, Nacher M, Montanya E, Mourad N, Buemi A, Citi V, Martelli A, Benedetti G, Calderone V, Rossi L, Paolicchi A, Cardarelli F, Dotta F, Eizirik DL, Ibberson M, Marchetti P, Cnop M, Marselli L

Open source

DOI: 10.1126/sciadv.ads2905
Published: 2025 Oct 10
Container: Science advances
Publisher: Not recorded
Open access: yes

Credibility signals

limited evidence Score 45/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

cautionDOI registered: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
cautionDOI resolves: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
supportingOpen access status: Normalized open-access status: open. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1126/sciadv.ads2905,
  title = {Functional recovery of islet β cells in human type 2 diabetes: Transcriptome signatures unveil therapeutic approaches.},
  author = {Suleiman M and Sawatani T and Tesi M and Yi X and Papadopoulou T and Rufer C and Lytrivi M and Bosi E and Burdet F and Fantuzzi F and De Luca C and Sebastiani G and Saponaro C and Pugliese LA and Del Guerra S and Pocai A and De Simone P and Ghinolfi D and Boggi U and Kessler C and Grieco GE and Fignani D and Kerr-Conte J and Pattou F and Nacher M and Montanya E and Mourad N and Buemi A and Citi V and Martelli A and Benedetti G and Calderone V and Rossi L and Paolicchi A and Cardarelli F and Dotta F and Eizirik DL and Ibberson M and Marchetti P and Cnop M and Marselli L},
  year = {2025},
  journal = {Science advances},
  doi = {10.1126/sciadv.ads2905},
  url = {https://doi.org/10.1126/sciadv.ads2905}
}

RIS

TY  - JOUR
TI  - Functional recovery of islet β cells in human type 2 diabetes: Transcriptome signatures unveil therapeutic approaches.
AU  - Suleiman M
AU  - Sawatani T
AU  - Tesi M
AU  - Yi X
AU  - Papadopoulou T
AU  - Rufer C
AU  - Lytrivi M
AU  - Bosi E
AU  - Burdet F
AU  - Fantuzzi F
AU  - De Luca C
AU  - Sebastiani G
AU  - Saponaro C
AU  - Pugliese LA
AU  - Del Guerra S
AU  - Pocai A
AU  - De Simone P
AU  - Ghinolfi D
AU  - Boggi U
AU  - Kessler C
AU  - Grieco GE
AU  - Fignani D
AU  - Kerr-Conte J
AU  - Pattou F
AU  - Nacher M
AU  - Montanya E
AU  - Mourad N
AU  - Buemi A
AU  - Citi V
AU  - Martelli A
AU  - Benedetti G
AU  - Calderone V
AU  - Rossi L
AU  - Paolicchi A
AU  - Cardarelli F
AU  - Dotta F
AU  - Eizirik DL
AU  - Ibberson M
AU  - Marchetti P
AU  - Cnop M
AU  - Marselli L
PY  - 2025
JO  - Science advances
DO  - 10.1126/sciadv.ads2905
UR  - https://doi.org/10.1126/sciadv.ads2905
ER  -

APA

M, S., T, S., M, T., X, Y., T, P., C, R., M, L., E, B., F, B., F, F., C, D. L., G, S., C, S., LA, P., S, D. G., A, P., P, D. S., D, G., U, B., C, K., GE, G., D, F., J, K., F, P., M, N., E, M., N, M., A, B., V, C., A, M., G, B., V, C., L, R., A, P., F, C., F, D., DL, E., M, I., P, M., M, C., & L, M. (2025). Functional recovery of islet β cells in human type 2 diabetes: Transcriptome signatures unveil therapeutic approaches.. Science advances. https://doi.org/10.1126/sciadv.ads2905

Source records

pubmed · retrieved 2026-09-26T10:48:33.276Z