The FAP × CD3 bispecific antibody OMTX305 induces T cell-mediated antitumor effects in patient-derived ex vivo models of solid tumors.

Thiel J, Schlegel JA, Liang C, Mürdter TE, Kneer A, Dreher S, Schäfer A, Seifert O, Kühl L, Preissler G, Simon L, Fabre M, Egaña I, Kurz KS, Ott G, Kontermann RE, Aulitzky WE, Schwab M, Olayioye MA, Dong M

Open source

DOI: 10.1126/sciadv.aee2124
Published: 2026 Sep 11
Container: Science advances
Publisher: Not recorded
Open access: yes

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Cite this work

BibTeX

@article{allodium:10.1126/sciadv.aee2124,
  title = {The FAP × CD3 bispecific antibody OMTX305 induces T cell-mediated antitumor effects in patient-derived ex vivo models of solid tumors.},
  author = {Thiel J and Schlegel JA and Liang C and Mürdter TE and Kneer A and Dreher S and Schäfer A and Seifert O and Kühl L and Preissler G and Simon L and Fabre M and Egaña I and Kurz KS and Ott G and Kontermann RE and Aulitzky WE and Schwab M and Olayioye MA and Dong M},
  year = {2026},
  journal = {Science advances},
  doi = {10.1126/sciadv.aee2124},
  url = {https://doi.org/10.1126/sciadv.aee2124}
}

RIS

TY  - JOUR
TI  - The FAP × CD3 bispecific antibody OMTX305 induces T cell-mediated antitumor effects in patient-derived ex vivo models of solid tumors.
AU  - Thiel J
AU  - Schlegel JA
AU  - Liang C
AU  - Mürdter TE
AU  - Kneer A
AU  - Dreher S
AU  - Schäfer A
AU  - Seifert O
AU  - Kühl L
AU  - Preissler G
AU  - Simon L
AU  - Fabre M
AU  - Egaña I
AU  - Kurz KS
AU  - Ott G
AU  - Kontermann RE
AU  - Aulitzky WE
AU  - Schwab M
AU  - Olayioye MA
AU  - Dong M
PY  - 2026
JO  - Science advances
DO  - 10.1126/sciadv.aee2124
UR  - https://doi.org/10.1126/sciadv.aee2124
ER  -

APA

J, T., JA, S., C, L., TE, M., A, K., S, D., A, S., O, S., L, K., G, P., L, S., M, F., I, E., KS, K., G, O., RE, K., WE, A., M, S., MA, O., & M, D. (2026). The FAP × CD3 bispecific antibody OMTX305 induces T cell-mediated antitumor effects in patient-derived ex vivo models of solid tumors.. Science advances. https://doi.org/10.1126/sciadv.aee2124

Source records

pubmed · retrieved 2026-09-24T22:27:51.666Z