The (amide-)N-methylnicotinamide is a microbe-derived NAD <sup>+</sup> precursor that drives gut stem cell renewal

Jiangmeng Han, Jayson M. Antonio, Jagannatham Naidu Bhupana, Garam Choi, Jiaxing Yang, Eric Chiles, Yan Tong, Mohamed Asik Rajmohamed, Hung-Ting Wu, Dahui Wang, Vik Meadows, Nicolas Lapaque, Jean-Pierre Etchegaray, Rafal Filip, Ta-Chiang Liu, Pawel R. Kiela, Nicholas Bessman, Ronaldo P. Ferraris, Ching-On Wong, Xiaoyang Su, Nan Gao

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DOI: 10.1126/sciadv.aef2882
Published: 2026-11-06
Container: Science Advances
Publisher: American Association for the Advancement of Science (AAAS)
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1126/sciadv.aef2882,
  title = {The (amide-)N-methylnicotinamide is a microbe-derived NAD
                    <sup>+</sup>
                    precursor that drives gut stem cell renewal},
  author = {Jiangmeng Han and Jayson M. Antonio and Jagannatham Naidu Bhupana and Garam Choi and Jiaxing Yang and Eric Chiles and Yan Tong and Mohamed Asik Rajmohamed and Hung-Ting Wu and Dahui Wang and Vik Meadows and Nicolas Lapaque and Jean-Pierre Etchegaray and Rafal Filip and Ta-Chiang Liu and Pawel R. Kiela and Nicholas Bessman and Ronaldo P. Ferraris and Ching-On Wong and Xiaoyang Su and Nan Gao},
  year = {2026},
  journal = {Science Advances},
  doi = {10.1126/sciadv.aef2882},
  url = {https://doi.org/10.1126/sciadv.aef2882}
}

RIS

TY  - JOUR
TI  - The (amide-)N-methylnicotinamide is a microbe-derived NAD
                    <sup>+</sup>
                    precursor that drives gut stem cell renewal
AU  - Jiangmeng Han
AU  - Jayson M. Antonio
AU  - Jagannatham Naidu Bhupana
AU  - Garam Choi
AU  - Jiaxing Yang
AU  - Eric Chiles
AU  - Yan Tong
AU  - Mohamed Asik Rajmohamed
AU  - Hung-Ting Wu
AU  - Dahui Wang
AU  - Vik Meadows
AU  - Nicolas Lapaque
AU  - Jean-Pierre Etchegaray
AU  - Rafal Filip
AU  - Ta-Chiang Liu
AU  - Pawel R. Kiela
AU  - Nicholas Bessman
AU  - Ronaldo P. Ferraris
AU  - Ching-On Wong
AU  - Xiaoyang Su
AU  - Nan Gao
PY  - 2026
JO  - Science Advances
DO  - 10.1126/sciadv.aef2882
UR  - https://doi.org/10.1126/sciadv.aef2882
ER  -

APA

Han, J., Antonio, J. M., Bhupana, J. N., Choi, G., Yang, J., Chiles, E., Tong, Y., Rajmohamed, M. A., Wu, H., Wang, D., Meadows, V., Lapaque, N., Etchegaray, J., Filip, R., Liu, T., Kiela, P. R., Bessman, N., Ferraris, R. P., Wong, C., Su, X., & Gao, N. (2026). The (amide-)N-methylnicotinamide is a microbe-derived NAD <sup>+</sup> precursor that drives gut stem cell renewal. Science Advances. https://doi.org/10.1126/sciadv.aef2882

Source records

crossref · retrieved 2026-11-08T11:47:02.962Z