Substrate-bound structures of yeast ALA synthase reveal protein dynamics initiating heme biosynthesis

Jenny U. Tran, Thyandra A. Martinez, Christopher Jurich, Margaret R. Josling, Julian M. Zhang, Pedro H. Ayres-Galhardo, Jens Meiler, Zhongyue J. Yang, Jason A. MacGurn, Breann L. Brown

Open source

DOI
10.1126/sciadv.aef7768
Published
2026-10-16
Container
Science Advances
Publisher
American Association for the Advancement of Science (AAAS)
Open access
unknown

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BibTeX

@article{allodium:10.1126/sciadv.aef7768,
  title = {Substrate-bound structures of yeast ALA synthase reveal protein dynamics initiating heme biosynthesis},
  author = {Jenny U. Tran and Thyandra A. Martinez and Christopher Jurich and Margaret R. Josling and Julian M. Zhang and Pedro H. Ayres-Galhardo and Jens Meiler and Zhongyue J. Yang and Jason A. MacGurn and Breann L. Brown},
  year = {2026},
  journal = {Science Advances},
  doi = {10.1126/sciadv.aef7768},
  url = {https://doi.org/10.1126/sciadv.aef7768}
}

RIS

TY  - JOUR
TI  - Substrate-bound structures of yeast ALA synthase reveal protein dynamics initiating heme biosynthesis
AU  - Jenny U. Tran
AU  - Thyandra A. Martinez
AU  - Christopher Jurich
AU  - Margaret R. Josling
AU  - Julian M. Zhang
AU  - Pedro H. Ayres-Galhardo
AU  - Jens Meiler
AU  - Zhongyue J. Yang
AU  - Jason A. MacGurn
AU  - Breann L. Brown
PY  - 2026
JO  - Science Advances
DO  - 10.1126/sciadv.aef7768
UR  - https://doi.org/10.1126/sciadv.aef7768
ER  - 

APA

Tran, J. U., Martinez, T. A., Jurich, C., Josling, M. R., Zhang, J. M., Ayres-Galhardo, P. H., Meiler, J., Yang, Z. J., MacGurn, J. A., & Brown, B. L. (2026). Substrate-bound structures of yeast ALA synthase reveal protein dynamics initiating heme biosynthesis. Science Advances. https://doi.org/10.1126/sciadv.aef7768

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