LAMP2A gene therapy mitigates Parkinson's disease-related pathology in nonhuman primates.

Arotcarena ML, Fouka M, Gialinaki EG, Giannopoulou M, Jadot H, Darricau M, Lovisotto A, Dovero S, Planche V, Balpe E, Achour M, Thiolat ML, Dutheil N, Li Q, Noe E, Pioli EY, Harhouri K, Steinschneider R, Kirik D, Jensen NM, Jensen PH, Stefanis L, Bezard E, Dehay B, Xilouri M

Open source

DOI: 10.1126/sciadv.aeg1787
Published: 2026 Oct 30
Container: Science advances
Publisher: Not recorded
Open access: yes

Credibility signals

limited evidence Score 45/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

cautionDOI registered: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
cautionDOI resolves: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
supportingOpen access status: Normalized open-access status: open. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1126/sciadv.aeg1787,
  title = {LAMP2A gene therapy mitigates Parkinson's disease-related pathology in nonhuman primates.},
  author = {Arotcarena ML and Fouka M and Gialinaki EG and Giannopoulou M and Jadot H and Darricau M and Lovisotto A and Dovero S and Planche V and Balpe E and Achour M and Thiolat ML and Dutheil N and Li Q and Noe E and Pioli EY and Harhouri K and Steinschneider R and Kirik D and Jensen NM and Jensen PH and Stefanis L and Bezard E and Dehay B and Xilouri M},
  year = {2026},
  journal = {Science advances},
  doi = {10.1126/sciadv.aeg1787},
  url = {https://doi.org/10.1126/sciadv.aeg1787}
}

RIS

TY  - JOUR
TI  - LAMP2A gene therapy mitigates Parkinson's disease-related pathology in nonhuman primates.
AU  - Arotcarena ML
AU  - Fouka M
AU  - Gialinaki EG
AU  - Giannopoulou M
AU  - Jadot H
AU  - Darricau M
AU  - Lovisotto A
AU  - Dovero S
AU  - Planche V
AU  - Balpe E
AU  - Achour M
AU  - Thiolat ML
AU  - Dutheil N
AU  - Li Q
AU  - Noe E
AU  - Pioli EY
AU  - Harhouri K
AU  - Steinschneider R
AU  - Kirik D
AU  - Jensen NM
AU  - Jensen PH
AU  - Stefanis L
AU  - Bezard E
AU  - Dehay B
AU  - Xilouri M
PY  - 2026
JO  - Science advances
DO  - 10.1126/sciadv.aeg1787
UR  - https://doi.org/10.1126/sciadv.aeg1787
ER  -

APA

ML, A., M, F., EG, G., M, G., H, J., M, D., A, L., S, D., V, P., E, B., M, A., ML, T., N, D., Q, L., E, N., EY, P., K, H., R, S., D, K., NM, J., PH, J., L, S., E, B., B, D., & M, X. (2026). LAMP2A gene therapy mitigates Parkinson's disease-related pathology in nonhuman primates.. Science advances. https://doi.org/10.1126/sciadv.aeg1787

Source records

pubmed · retrieved 2026-11-10T19:52:00.023Z