Dose-dependent sensitivity of human three-dimensional chromatin to a heart disease-linked transcription factor.

Grant ZL, Kuang S, Zhang S, Horrillo AJ, Chen Z, Rao KS, Celen C, Kameswaran V, Joubran C, Lau PK, Dong K, Yang B, Bartosik WM, Zemke NR, Ren B, Srivastava D, Kathiriya IS, Pollard KS, Bruneau BG

Open source

DOI: 10.1126/science.adv5434
Published: 2026 Jul 23
Container: Science (New York, N.Y.)
Publisher: Not recorded
Open access: yes

Credibility signals

limited evidence Score 45/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

cautionDOI registered: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
cautionDOI resolves: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
supportingOpen access status: Normalized open-access status: open. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1126/science.adv5434,
  title = {Dose-dependent sensitivity of human three-dimensional chromatin to a heart disease-linked transcription factor.},
  author = {Grant ZL and Kuang S and Zhang S and Horrillo AJ and Chen Z and Rao KS and Celen C and Kameswaran V and Joubran C and Lau PK and Dong K and Yang B and Bartosik WM and Zemke NR and Ren B and Srivastava D and Kathiriya IS and Pollard KS and Bruneau BG},
  year = {2026},
  journal = {Science (New York, N.Y.)},
  doi = {10.1126/science.adv5434},
  url = {https://doi.org/10.1126/science.adv5434}
}

RIS

TY  - JOUR
TI  - Dose-dependent sensitivity of human three-dimensional chromatin to a heart disease-linked transcription factor.
AU  - Grant ZL
AU  - Kuang S
AU  - Zhang S
AU  - Horrillo AJ
AU  - Chen Z
AU  - Rao KS
AU  - Celen C
AU  - Kameswaran V
AU  - Joubran C
AU  - Lau PK
AU  - Dong K
AU  - Yang B
AU  - Bartosik WM
AU  - Zemke NR
AU  - Ren B
AU  - Srivastava D
AU  - Kathiriya IS
AU  - Pollard KS
AU  - Bruneau BG
PY  - 2026
JO  - Science (New York, N.Y.)
DO  - 10.1126/science.adv5434
UR  - https://doi.org/10.1126/science.adv5434
ER  -

APA

ZL, G., S, K., S, Z., AJ, H., Z, C., KS, R., C, C., V, K., C, J., PK, L., K, D., B, Y., WM, B., NR, Z., B, R., D, S., IS, K., KS, P., & BG, B. (2026). Dose-dependent sensitivity of human three-dimensional chromatin to a heart disease-linked transcription factor.. Science (New York, N.Y.). https://doi.org/10.1126/science.adv5434

Source records

pubmed · retrieved 2026-09-25T09:19:43.945Z