Atlas of lysosomal aging reveals a metabolite signature shared with lysosomal storage disorders.

Puszynska AM, Nguyen TP, Cangelosi AL, Armani A, Roberts JM, Singh KA, Cameron JC, Tseyang T, Liu GY, Lai S, Sprenger HG, Yang J, Colgan WN, Kedir JF, Kajderowicz KM, Esantsi TK, Lu YR, Waite M, Kunchok T, Lewis CA, Schulte F, Bell GW, Sabatini DM, Weissman JS

Open source

DOI: 10.1126/science.ady0832
Published: 2026 Jul 30
Container: Science (New York, N.Y.)
Publisher: Not recorded
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1126/science.ady0832,
  title = {Atlas of lysosomal aging reveals a metabolite signature shared with lysosomal storage disorders.},
  author = {Puszynska AM and Nguyen TP and Cangelosi AL and Armani A and Roberts JM and Singh KA and Cameron JC and Tseyang T and Liu GY and Lai S and Sprenger HG and Yang J and Colgan WN and Kedir JF and Kajderowicz KM and Esantsi TK and Lu YR and Waite M and Kunchok T and Lewis CA and Schulte F and Bell GW and Sabatini DM and Weissman JS},
  year = {2026},
  journal = {Science (New York, N.Y.)},
  doi = {10.1126/science.ady0832},
  url = {https://doi.org/10.1126/science.ady0832}
}

RIS

TY  - JOUR
TI  - Atlas of lysosomal aging reveals a metabolite signature shared with lysosomal storage disorders.
AU  - Puszynska AM
AU  - Nguyen TP
AU  - Cangelosi AL
AU  - Armani A
AU  - Roberts JM
AU  - Singh KA
AU  - Cameron JC
AU  - Tseyang T
AU  - Liu GY
AU  - Lai S
AU  - Sprenger HG
AU  - Yang J
AU  - Colgan WN
AU  - Kedir JF
AU  - Kajderowicz KM
AU  - Esantsi TK
AU  - Lu YR
AU  - Waite M
AU  - Kunchok T
AU  - Lewis CA
AU  - Schulte F
AU  - Bell GW
AU  - Sabatini DM
AU  - Weissman JS
PY  - 2026
JO  - Science (New York, N.Y.)
DO  - 10.1126/science.ady0832
UR  - https://doi.org/10.1126/science.ady0832
ER  -

APA

AM, P., TP, N., AL, C., A, A., JM, R., KA, S., JC, C., T, T., GY, L., S, L., HG, S., J, Y., WN, C., JF, K., KM, K., TK, E., YR, L., M, W., T, K., CA, L., F, S., GW, B., DM, S., & JS, W. (2026). Atlas of lysosomal aging reveals a metabolite signature shared with lysosomal storage disorders.. Science (New York, N.Y.). https://doi.org/10.1126/science.ady0832

Source records

pubmed · retrieved 2026-11-10T09:56:17.232Z