Early-life colonization with <i>Clostridioides difficile</i> remodels the developing gut

Alexa Semon, Haider S. Manzer, Orlaith Keenan, Tiffany H. Zhou, Connor Tiffany, Qianxuan She, Montana Knight, Ashley S. Weiss, Kassy Donohoe, Brendan T. Morrow, Rochelle C. Glover, Maria E. Kovalik, Ceylan Tanes, Kyle Bittinger, Babette S. Zemel, Gary D. Wu, Michael A. Silverman, Jeffrey S. Gerber, Rubén Cano Rodríguez, D. Borden Lacy, Tatiana A. Karakasheva, Mohamad-Gabriel Alameh, Drew Weissman, Stacey L. Schultz-Cherry, Jason W. Rosch, Paul J. Planet, Ahmed M. Moustafa, Emma E. Furth, Michael C. Abt, Judith R. Kelsen, Maire A. Conrad, Kathryn E. Hamilton, Joseph P. Zackular

Open source

DOI: 10.1126/science.ady2886
Published: 2026-09-03
Container: Science
Publisher: American Association for the Advancement of Science (AAAS)
Open access: unknown

Credibility signals

uncertain Score 64/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

supportingDOI registered: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
supportingDOI resolves: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredOpen access status: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
supportingMetadata completeness: All 6 scored descriptive metadata groups are present. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.1126/science.ady2886,
  title = {Early-life colonization with
                    <i>Clostridioides difficile</i>
                    remodels the developing gut},
  author = {Alexa Semon and Haider S. Manzer and Orlaith Keenan and Tiffany H. Zhou and Connor Tiffany and Qianxuan She and Montana Knight and Ashley S. Weiss and Kassy Donohoe and Brendan T. Morrow and Rochelle C. Glover and Maria E. Kovalik and Ceylan Tanes and Kyle Bittinger and Babette S. Zemel and Gary D. Wu and Michael A. Silverman and Jeffrey S. Gerber and Rubén Cano Rodríguez and D. Borden Lacy and Tatiana A. Karakasheva and Mohamad-Gabriel Alameh and Drew Weissman and Stacey L. Schultz-Cherry and Jason W. Rosch and Paul J. Planet and Ahmed M. Moustafa and Emma E. Furth and Michael C. Abt and Judith R. Kelsen and Maire A. Conrad and Kathryn E. Hamilton and Joseph P. Zackular},
  year = {2026},
  journal = {Science},
  doi = {10.1126/science.ady2886},
  url = {https://doi.org/10.1126/science.ady2886}
}

RIS

TY  - JOUR
TI  - Early-life colonization with
                    <i>Clostridioides difficile</i>
                    remodels the developing gut
AU  - Alexa Semon
AU  - Haider S. Manzer
AU  - Orlaith Keenan
AU  - Tiffany H. Zhou
AU  - Connor Tiffany
AU  - Qianxuan She
AU  - Montana Knight
AU  - Ashley S. Weiss
AU  - Kassy Donohoe
AU  - Brendan T. Morrow
AU  - Rochelle C. Glover
AU  - Maria E. Kovalik
AU  - Ceylan Tanes
AU  - Kyle Bittinger
AU  - Babette S. Zemel
AU  - Gary D. Wu
AU  - Michael A. Silverman
AU  - Jeffrey S. Gerber
AU  - Rubén Cano Rodríguez
AU  - D. Borden Lacy
AU  - Tatiana A. Karakasheva
AU  - Mohamad-Gabriel Alameh
AU  - Drew Weissman
AU  - Stacey L. Schultz-Cherry
AU  - Jason W. Rosch
AU  - Paul J. Planet
AU  - Ahmed M. Moustafa
AU  - Emma E. Furth
AU  - Michael C. Abt
AU  - Judith R. Kelsen
AU  - Maire A. Conrad
AU  - Kathryn E. Hamilton
AU  - Joseph P. Zackular
PY  - 2026
JO  - Science
DO  - 10.1126/science.ady2886
UR  - https://doi.org/10.1126/science.ady2886
ER  -

APA

Semon, A., Manzer, H. S., Keenan, O., Zhou, T. H., Tiffany, C., She, Q., Knight, M., Weiss, A. S., Donohoe, K., Morrow, B. T., Glover, R. C., Kovalik, M. E., Tanes, C., Bittinger, K., Zemel, B. S., Wu, G. D., Silverman, M. A., Gerber, J. S., Rodríguez, R. C., Lacy, D. B., Karakasheva, T. A., Alameh, M., Weissman, D., Schultz-Cherry, S. L., Rosch, J. W., Planet, P. J., Moustafa, A. M., Furth, E. E., Abt, M. C., Kelsen, J. R., Conrad, M. A., Hamilton, K. E., & Zackular, J. P. (2026). Early-life colonization with <i>Clostridioides difficile</i> remodels the developing gut. Science. https://doi.org/10.1126/science.ady2886

Source records

crossref · retrieved 2026-11-10T18:00:16.773Z