De novo design of RNA pseudoknots with deep learning

Jill Townley, Wipapat Kladwang, David Baker, Hamish M. Blair, Christian A. Choe, Gina El Nesr, Andrew Favor, Eli Fisker, Daniel B. Haack, Shujun He, Jason Hingey, Po-Ssu Huang, Rui Huang, Chaitanya K. Joshi, Thomas Karagianes, Andrew Kubaney, Pietro Liò, Adamo Mancino, Jonathan Romano, Boris Rudolfs, Nicholas Spellmon, Navtej Toor, Jigyasa Verma, Vivian Wu, Zhiheng Yu, Eterna Participants, Rhiju Das

Open source

DOI
10.1126/science.aeg6829
Published
2026-08-27
Container
Science
Publisher
American Association for the Advancement of Science (AAAS)
Open access
unknown

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BibTeX

@article{allodium:10.1126/science.aeg6829,
  title = {De novo design of RNA pseudoknots with deep learning},
  author = {Jill Townley and Wipapat Kladwang and David Baker and Hamish M. Blair and Christian A. Choe and Gina El Nesr and Andrew Favor and Eli Fisker and Daniel B. Haack and Shujun He and Jason Hingey and Po-Ssu Huang and Rui Huang and Chaitanya K. Joshi and Thomas Karagianes and Andrew Kubaney and Pietro Liò and Adamo Mancino and Jonathan Romano and Boris Rudolfs and Nicholas Spellmon and Navtej Toor and Jigyasa Verma and Vivian Wu and Zhiheng Yu and Eterna Participants and Rhiju Das},
  year = {2026},
  journal = {Science},
  doi = {10.1126/science.aeg6829},
  url = {https://doi.org/10.1126/science.aeg6829}
}

RIS

TY  - JOUR
TI  - De novo design of RNA pseudoknots with deep learning
AU  - Jill Townley
AU  - Wipapat Kladwang
AU  - David Baker
AU  - Hamish M. Blair
AU  - Christian A. Choe
AU  - Gina El Nesr
AU  - Andrew Favor
AU  - Eli Fisker
AU  - Daniel B. Haack
AU  - Shujun He
AU  - Jason Hingey
AU  - Po-Ssu Huang
AU  - Rui Huang
AU  - Chaitanya K. Joshi
AU  - Thomas Karagianes
AU  - Andrew Kubaney
AU  - Pietro Liò
AU  - Adamo Mancino
AU  - Jonathan Romano
AU  - Boris Rudolfs
AU  - Nicholas Spellmon
AU  - Navtej Toor
AU  - Jigyasa Verma
AU  - Vivian Wu
AU  - Zhiheng Yu
AU  - Eterna Participants
AU  - Rhiju Das
PY  - 2026
JO  - Science
DO  - 10.1126/science.aeg6829
UR  - https://doi.org/10.1126/science.aeg6829
ER  - 

APA

Townley, J., Kladwang, W., Baker, D., Blair, H. M., Choe, C. A., Nesr, G. E., Favor, A., Fisker, E., Haack, D. B., He, S., Hingey, J., Huang, P., Huang, R., Joshi, C. K., Karagianes, T., Kubaney, A., Liò, P., Mancino, A., Romano, J., Rudolfs, B., Spellmon, N., Toor, N., Verma, J., Wu, V., Yu, Z., Participants, E., & Das, R. (2026). De novo design of RNA pseudoknots with deep learning. Science. https://doi.org/10.1126/science.aeg6829

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