SGLT2 inhibitors activate pantothenate kinase in the human heart

Nicholas Forelli, Trace Thome, Deborah M. Eaton, Kollin Schultz, Jiten Patel, Caitlyn E. Bowman, Ryo Kawakami, Jae Woo Jung, Ivan A. Kuznetsov, Kristina Li, Jialiu A. Liang, Kirsten Branch, Claire Brady, Kenneth C. Bedi, Yijun Yang, Kaustubh Koya, Nesrine Bouhrira, Emily Megill, Daniel S. Kantner, Louis G. Smith, Cristin F. MacIntosh, Kushol Gupta, Gregory R. Bowman, Nathaniel W. Snyder, Jonathan Edwards, Kenneth B. Margulies, Zoltan Arany

Open source

DOI: 10.1126/science.aeh4856
Published: 2026-08-27
Container: Science
Publisher: American Association for the Advancement of Science (AAAS)
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1126/science.aeh4856,
  title = {SGLT2 inhibitors activate pantothenate kinase in the human heart},
  author = {Nicholas Forelli and Trace Thome and Deborah M. Eaton and Kollin Schultz and Jiten Patel and Caitlyn E. Bowman and Ryo Kawakami and Jae Woo Jung and Ivan A. Kuznetsov and Kristina Li and Jialiu A. Liang and Kirsten Branch and Claire Brady and Kenneth C. Bedi and Yijun Yang and Kaustubh Koya and Nesrine Bouhrira and Emily Megill and Daniel S. Kantner and Louis G. Smith and Cristin F. MacIntosh and Kushol Gupta and Gregory R. Bowman and Nathaniel W. Snyder and Jonathan Edwards and Kenneth B. Margulies and Zoltan Arany},
  year = {2026},
  journal = {Science},
  doi = {10.1126/science.aeh4856},
  url = {https://doi.org/10.1126/science.aeh4856}
}

RIS

TY  - JOUR
TI  - SGLT2 inhibitors activate pantothenate kinase in the human heart
AU  - Nicholas Forelli
AU  - Trace Thome
AU  - Deborah M. Eaton
AU  - Kollin Schultz
AU  - Jiten Patel
AU  - Caitlyn E. Bowman
AU  - Ryo Kawakami
AU  - Jae Woo Jung
AU  - Ivan A. Kuznetsov
AU  - Kristina Li
AU  - Jialiu A. Liang
AU  - Kirsten Branch
AU  - Claire Brady
AU  - Kenneth C. Bedi
AU  - Yijun Yang
AU  - Kaustubh Koya
AU  - Nesrine Bouhrira
AU  - Emily Megill
AU  - Daniel S. Kantner
AU  - Louis G. Smith
AU  - Cristin F. MacIntosh
AU  - Kushol Gupta
AU  - Gregory R. Bowman
AU  - Nathaniel W. Snyder
AU  - Jonathan Edwards
AU  - Kenneth B. Margulies
AU  - Zoltan Arany
PY  - 2026
JO  - Science
DO  - 10.1126/science.aeh4856
UR  - https://doi.org/10.1126/science.aeh4856
ER  -

APA

Forelli, N., Thome, T., Eaton, D. M., Schultz, K., Patel, J., Bowman, C. E., Kawakami, R., Jung, J. W., Kuznetsov, I. A., Li, K., Liang, J. A., Branch, K., Brady, C., Bedi, K. C., Yang, Y., Koya, K., Bouhrira, N., Megill, E., Kantner, D. S., Smith, L. G., MacIntosh, C. F., Gupta, K., Bowman, G. R., Snyder, N. W., Edwards, J., Margulies, K. B., & Arany, Z. (2026). SGLT2 inhibitors activate pantothenate kinase in the human heart. Science. https://doi.org/10.1126/science.aeh4856

Source records

crossref · retrieved 2026-11-10T12:51:38.335Z