An N-terminal CDC42 T43I variant reveals the mechanism of pyrin inflammasome activation.

Aoki M, Iannuzzo A, Mertz P, Feng S, Iwata N, Perugini C, Tsuchida N, El Masri R, Kuchitsu Y, Tacine R, Coppola S, Shibata H, Cescato M, Nishitani-Isa M, Terré A, Kawasaki Y, Dalmon S, Nishimura K, Magnotti F, Miyatake S, André M, Hamada K, London J, Izawa K, Niwa A, Okamoto N, Ogata K, Nishikawa M, Zara E, Saito MK, Tartaglia M, Ito S, Rodero MP, Nagata KI, Smahi A, Matsumoto N, Le Corre L, Takita J, Boursier G, Hijikata A, Henry T, Taguchi T, Hentgen V, Georgin-Lavialle S, Honda Y, Masters SL, Yasumi T, Delon J

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DOI: 10.1126/sciimmunol.aea0515
Published: 2026 Aug 7
Container: Science immunology
Publisher: Not recorded
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1126/sciimmunol.aea0515,
  title = {An N-terminal CDC42 T43I variant reveals the mechanism of pyrin inflammasome activation.},
  author = {Aoki M and Iannuzzo A and Mertz P and Feng S and Iwata N and Perugini C and Tsuchida N and El Masri R and Kuchitsu Y and Tacine R and Coppola S and Shibata H and Cescato M and Nishitani-Isa M and Terré A and Kawasaki Y and Dalmon S and Nishimura K and Magnotti F and Miyatake S and André M and Hamada K and London J and Izawa K and Niwa A and Okamoto N and Ogata K and Nishikawa M and Zara E and Saito MK and Tartaglia M and Ito S and Rodero MP and Nagata KI and Smahi A and Matsumoto N and Le Corre L and Takita J and Boursier G and Hijikata A and Henry T and Taguchi T and Hentgen V and Georgin-Lavialle S and Honda Y and Masters SL and Yasumi T and Delon J},
  year = {2026},
  journal = {Science immunology},
  doi = {10.1126/sciimmunol.aea0515},
  url = {https://doi.org/10.1126/sciimmunol.aea0515}
}

RIS

TY  - JOUR
TI  - An N-terminal CDC42 T43I variant reveals the mechanism of pyrin inflammasome activation.
AU  - Aoki M
AU  - Iannuzzo A
AU  - Mertz P
AU  - Feng S
AU  - Iwata N
AU  - Perugini C
AU  - Tsuchida N
AU  - El Masri R
AU  - Kuchitsu Y
AU  - Tacine R
AU  - Coppola S
AU  - Shibata H
AU  - Cescato M
AU  - Nishitani-Isa M
AU  - Terré A
AU  - Kawasaki Y
AU  - Dalmon S
AU  - Nishimura K
AU  - Magnotti F
AU  - Miyatake S
AU  - André M
AU  - Hamada K
AU  - London J
AU  - Izawa K
AU  - Niwa A
AU  - Okamoto N
AU  - Ogata K
AU  - Nishikawa M
AU  - Zara E
AU  - Saito MK
AU  - Tartaglia M
AU  - Ito S
AU  - Rodero MP
AU  - Nagata KI
AU  - Smahi A
AU  - Matsumoto N
AU  - Le Corre L
AU  - Takita J
AU  - Boursier G
AU  - Hijikata A
AU  - Henry T
AU  - Taguchi T
AU  - Hentgen V
AU  - Georgin-Lavialle S
AU  - Honda Y
AU  - Masters SL
AU  - Yasumi T
AU  - Delon J
PY  - 2026
JO  - Science immunology
DO  - 10.1126/sciimmunol.aea0515
UR  - https://doi.org/10.1126/sciimmunol.aea0515
ER  -

APA

M, A., A, I., P, M., S, F., N, I., C, P., N, T., R, E. M., Y, K., R, T., S, C., H, S., M, C., M, N., A, T., Y, K., S, D., K, N., F, M., S, M., M, A., K, H., J, L., K, I., A, N., N, O., K, O., M, N., E, Z., MK, S., M, T., S, I., MP, R., KI, N., A, S., N, M., L, L. C., J, T., G, B., A, H., T, H., T, T., V, H., S, G., Y, H., SL, M., T, Y., & J, D. (2026). An N-terminal CDC42 T43I variant reveals the mechanism of pyrin inflammasome activation.. Science immunology. https://doi.org/10.1126/sciimmunol.aea0515

Source records

pubmed · retrieved 2026-09-25T00:53:41.032Z