Progression to rheumatoid arthritis in at-risk individuals is defined by systemic inflammation and by T and B cell dysregulation

Ziyuan He, Marla C. Glass, Pravina Venkatesan, Marie L. Feser, Leander Lazaro, Lauren Y. Okada, Nhung T. T. Tran, Yudong D. He, Samir Rachid Zaim, Christy E. Bennett, Padmapriyadarshini Ravisankar, Elisabeth M. Dornisch, Alexandra C. Ferrannini, Najeeb A. Arishi, Ashley G. Asamoah, Saman Barzideh, Lynne A. Becker, Elizabeth A. Bemis, Jane H. Buckner, Christopher E. Collora, Megan A. L. Criley, M. Kristen Demoruelle, Chelsie L. Fleischer, Jessica Garber, Palak C. Genge, Qiuyu Gong, Lucas T. Graybuck, Claire E. Gustafson, Brian C. Hattel, Veronica Hernandez, Alexander T. Heubeck, Erin K. Kawelo, Upaasana Krishnan, Emma L. Kuan, Kristine A. Kuhn, Christian M. LaFrance, Kevin J. Lee, Ruoxin Li, Cara Lord, Regina R. Mettey, Laura Moss, Blessing Musgrove, Katherine HY Nguyen, Andrea Ochoa, Vaishnavi Parthasarathy, Mark-Phillip Pebworth, Chong Pedrick, Tao Peng, Cole G. Phalen, Julian Reading, Charles R. Roll, Jennifer A. Seifert, Marguerite D. Siedschlag, Cate Speake, Christopher C. Striebich, Tyanna J. Stuckey, Elliott G. Swanson, Hideto Takada, Tylor Thai, Zachary J. Thomson, Nguyen Trieu, Vlad Tsaltskan, Wei Wang, Morgan D. A. Weiss, Amy Westermann, Fan Zhang, David L. Boyle, Ananda W. Goldrath, Thomas F. Bumol, Xiao-jun Li, V. Michael Holers, Peter J. Skene, Adam K. Savage, Gary S. Firestein, Kevin D. Deane, Troy R. Torgerson, Mark A. Gillespie

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DOI: 10.1126/scitranslmed.adt7214
Published: 2025-09-24
Container: Science Translational Medicine
Publisher: American Association for the Advancement of Science (AAAS)
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1126/scitranslmed.adt7214,
title = {Progression to rheumatoid arthritis in at-risk individuals is defined by systemic inflammation and by T and B cell dysregulation},
author = {Ziyuan He and Marla C. Glass and Pravina Venkatesan and Marie L. Feser and Leander Lazaro and Lauren Y. Okada and Nhung T. T. Tran and Yudong D. He and Samir Rachid Zaim and Christy E. Bennett and Padmapriyadarshini Ravisankar and Elisabeth M. Dornisch and Alexandra C. Ferrannini and Najeeb A. Arishi and Ashley G. Asamoah and Saman Barzideh and Lynne A. Becker and Elizabeth A. Bemis and Jane H. Buckner and Christopher E. Collora and Megan A. L. Criley and M. Kristen Demoruelle and Chelsie L. Fleischer and Jessica Garber and Palak C. Genge and Qiuyu Gong and Lucas T. Graybuck and Claire E. Gustafson and Brian C. Hattel and Veronica Hernandez and Alexander T. Heubeck and Erin K. Kawelo and Upaasana Krishnan and Emma L. Kuan and Kristine A. Kuhn and Christian M. LaFrance and Kevin J. Lee and Ruoxin Li and Cara Lord and Regina R. Mettey and Laura Moss and Blessing Musgrove and Katherine HY Nguyen and Andrea Ochoa and Vaishnavi Parthasarathy and Mark-Phillip Pebworth and Chong Pedrick and Tao Peng and Cole G. Phalen and Julian Reading and Charles R. Roll and Jennifer A. Seifert and Marguerite D. Siedschlag and Cate Speake and Christopher C. Striebich and Tyanna J. Stuckey and Elliott G. Swanson and Hideto Takada and Tylor Thai and Zachary J. Thomson and Nguyen Trieu and Vlad Tsaltskan and Wei Wang and Morgan D. A. Weiss and Amy Westermann and Fan Zhang and David L. Boyle and Ananda W. Goldrath and Thomas F. Bumol and Xiao-jun Li and V. Michael Holers and Peter J. Skene and Adam K. Savage and Gary S. Firestein and Kevin D. Deane and Troy R. Torgerson and Mark A. Gillespie},
year = {2025},
journal = {Science Translational Medicine},
doi = {10.1126/scitranslmed.adt7214},
url = {https://doi.org/10.1126/scitranslmed.adt7214}
}

RIS

TY  - JOUR
TI  - Progression to rheumatoid arthritis in at-risk individuals is defined by systemic inflammation and by T and B cell dysregulation
AU  - Ziyuan He
AU  - Marla C. Glass
AU  - Pravina Venkatesan
AU  - Marie L. Feser
AU  - Leander Lazaro
AU  - Lauren Y. Okada
AU  - Nhung T. T. Tran
AU  - Yudong D. He
AU  - Samir Rachid Zaim
AU  - Christy E. Bennett
AU  - Padmapriyadarshini Ravisankar
AU  - Elisabeth M. Dornisch
AU  - Alexandra C. Ferrannini
AU  - Najeeb A. Arishi
AU  - Ashley G. Asamoah
AU  - Saman Barzideh
AU  - Lynne A. Becker
AU  - Elizabeth A. Bemis
AU  - Jane H. Buckner
AU  - Christopher E. Collora
AU  - Megan A. L. Criley
AU  - M. Kristen Demoruelle
AU  - Chelsie L. Fleischer
AU  - Jessica Garber
AU  - Palak C. Genge
AU  - Qiuyu Gong
AU  - Lucas T. Graybuck
AU  - Claire E. Gustafson
AU  - Brian C. Hattel
AU  - Veronica Hernandez
AU  - Alexander T. Heubeck
AU  - Erin K. Kawelo
AU  - Upaasana Krishnan
AU  - Emma L. Kuan
AU  - Kristine A. Kuhn
AU  - Christian M. LaFrance
AU  - Kevin J. Lee
AU  - Ruoxin Li
AU  - Cara Lord
AU  - Regina R. Mettey
AU  - Laura Moss
AU  - Blessing Musgrove
AU  - Katherine HY Nguyen
AU  - Andrea Ochoa
AU  - Vaishnavi Parthasarathy
AU  - Mark-Phillip Pebworth
AU  - Chong Pedrick
AU  - Tao Peng
AU  - Cole G. Phalen
AU  - Julian Reading
AU  - Charles R. Roll
AU  - Jennifer A. Seifert
AU  - Marguerite D. Siedschlag
AU  - Cate Speake
AU  - Christopher C. Striebich
AU  - Tyanna J. Stuckey
AU  - Elliott G. Swanson
AU  - Hideto Takada
AU  - Tylor Thai
AU  - Zachary J. Thomson
AU  - Nguyen Trieu
AU  - Vlad Tsaltskan
AU  - Wei Wang
AU  - Morgan D. A. Weiss
AU  - Amy Westermann
AU  - Fan Zhang
AU  - David L. Boyle
AU  - Ananda W. Goldrath
AU  - Thomas F. Bumol
AU  - Xiao-jun Li
AU  - V. Michael Holers
AU  - Peter J. Skene
AU  - Adam K. Savage
AU  - Gary S. Firestein
AU  - Kevin D. Deane
AU  - Troy R. Torgerson
AU  - Mark A. Gillespie
PY  - 2025
JO  - Science Translational Medicine
DO  - 10.1126/scitranslmed.adt7214
UR  - https://doi.org/10.1126/scitranslmed.adt7214
ER  -

APA

He, Z., Glass, M. C., Venkatesan, P., Feser, M. L., Lazaro, L., Okada, L. Y., Tran, N. T. T., He, Y. D., Zaim, S. R., Bennett, C. E., Ravisankar, P., Dornisch, E. M., Ferrannini, A. C., Arishi, N. A., Asamoah, A. G., Barzideh, S., Becker, L. A., Bemis, E. A., Buckner, J. H., Collora, C. E., Criley, M. A. L., Demoruelle, M. K., Fleischer, C. L., Garber, J., Genge, P. C., Gong, Q., Graybuck, L. T., Gustafson, C. E., Hattel, B. C., Hernandez, V., Heubeck, A. T., Kawelo, E. K., Krishnan, U., Kuan, E. L., Kuhn, K. A., LaFrance, C. M., Lee, K. J., Li, R., Lord, C., Mettey, R. R., Moss, L., Musgrove, B., Nguyen, K. H., Ochoa, A., Parthasarathy, V., Pebworth, M., Pedrick, C., Peng, T., Phalen, C. G., Reading, J., Roll, C. R., Seifert, J. A., Siedschlag, M. D., Speake, C., Striebich, C. C., Stuckey, T. J., Swanson, E. G., Takada, H., Thai, T., Thomson, Z. J., Trieu, N., Tsaltskan, V., Wang, W., Weiss, M. D. A., Westermann, A., Zhang, F., Boyle, D. L., Goldrath, A. W., Bumol, T. F., Li, X., Holers, V. M., Skene, P. J., Savage, A. K., Firestein, G. S., Deane, K. D., Torgerson, T. R., & Gillespie, M. A. (2025). Progression to rheumatoid arthritis in at-risk individuals is defined by systemic inflammation and by T and B cell dysregulation. Science Translational Medicine. https://doi.org/10.1126/scitranslmed.adt7214

Source records

crossref · retrieved 2026-09-26T08:14:28.593Z