Splicing-associated network PAK1-CLK1/4-SRRM1 is a vulnerability to overcome chemoresistance in human and mouse acute myeloid leukemia.

Vaganay C, Ling F, Kelly LM, Charles J, Meslin PA, Pasquer H, Kim R, Passet M, Duchmann M, Pelissier-Menjaud L, Lecourt S, Su AH, Latour E, Bassil CF, Alexe G, Fortin G, Nhat DH, Culeux C, Legrand C, Fodil S, Huynh T, Saadallah K, Ramos A, Lombard B, Loew D, Delaney CD, Lonchamp C, Fontaine M, Pacchiardi K, Kocijancic A, Aziez L, Fenouille N, Sebert M, Adès L, Raffoux E, Hemann MT, Clappier E, Benajiba L, Stegmaier K, Wood KC, Itzykson R, Forget A, Lobry C, Puissant A

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DOI: 10.1126/scitranslmed.adx3847
Published: 2026 Jul 8
Container: Science translational medicine
Publisher: Not recorded
Open access: yes

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Cite this work

BibTeX

@article{allodium:10.1126/scitranslmed.adx3847,
  title = {Splicing-associated network PAK1-CLK1/4-SRRM1 is a vulnerability to overcome chemoresistance in human and mouse acute myeloid leukemia.},
  author = {Vaganay C and Ling F and Kelly LM and Charles J and Meslin PA and Pasquer H and Kim R and Passet M and Duchmann M and Pelissier-Menjaud L and Lecourt S and Su AH and Latour E and Bassil CF and Alexe G and Fortin G and Nhat DH and Culeux C and Legrand C and Fodil S and Huynh T and Saadallah K and Ramos A and Lombard B and Loew D and Delaney CD and Lonchamp C and Fontaine M and Pacchiardi K and Kocijancic A and Aziez L and Fenouille N and Sebert M and Adès L and Raffoux E and Hemann MT and Clappier E and Benajiba L and Stegmaier K and Wood KC and Itzykson R and Forget A and Lobry C and Puissant A},
  year = {2026},
  journal = {Science translational medicine},
  doi = {10.1126/scitranslmed.adx3847},
  url = {https://doi.org/10.1126/scitranslmed.adx3847}
}

RIS

TY  - JOUR
TI  - Splicing-associated network PAK1-CLK1/4-SRRM1 is a vulnerability to overcome chemoresistance in human and mouse acute myeloid leukemia.
AU  - Vaganay C
AU  - Ling F
AU  - Kelly LM
AU  - Charles J
AU  - Meslin PA
AU  - Pasquer H
AU  - Kim R
AU  - Passet M
AU  - Duchmann M
AU  - Pelissier-Menjaud L
AU  - Lecourt S
AU  - Su AH
AU  - Latour E
AU  - Bassil CF
AU  - Alexe G
AU  - Fortin G
AU  - Nhat DH
AU  - Culeux C
AU  - Legrand C
AU  - Fodil S
AU  - Huynh T
AU  - Saadallah K
AU  - Ramos A
AU  - Lombard B
AU  - Loew D
AU  - Delaney CD
AU  - Lonchamp C
AU  - Fontaine M
AU  - Pacchiardi K
AU  - Kocijancic A
AU  - Aziez L
AU  - Fenouille N
AU  - Sebert M
AU  - Adès L
AU  - Raffoux E
AU  - Hemann MT
AU  - Clappier E
AU  - Benajiba L
AU  - Stegmaier K
AU  - Wood KC
AU  - Itzykson R
AU  - Forget A
AU  - Lobry C
AU  - Puissant A
PY  - 2026
JO  - Science translational medicine
DO  - 10.1126/scitranslmed.adx3847
UR  - https://doi.org/10.1126/scitranslmed.adx3847
ER  -

APA

C, V., F, L., LM, K., J, C., PA, M., H, P., R, K., M, P., M, D., L, P., S, L., AH, S., E, L., CF, B., G, A., G, F., DH, N., C, C., C, L., S, F., T, H., K, S., A, R., B, L., D, L., CD, D., C, L., M, F., K, P., A, K., L, A., N, F., M, S., L, A., E, R., MT, H., E, C., L, B., K, S., KC, W., R, I., A, F., C, L., & A, P. (2026). Splicing-associated network PAK1-CLK1/4-SRRM1 is a vulnerability to overcome chemoresistance in human and mouse acute myeloid leukemia.. Science translational medicine. https://doi.org/10.1126/scitranslmed.adx3847

Source records

pubmed · retrieved 2026-09-25T17:08:23.332Z