EGFR inhibition down-regulates MGMT and enhances responsiveness to temozolomide in glioblastoma

Arifa Nayab, Nouman Mughal, Meher Angez, Sansi Xing, Aarohan M. Burma, Harshitha Balla, Sani H. Kizilbash, Xiaoyao Yang, Muhammad Asad Maqbool, Fazal Arain, Azhar Hussain, Sahara Amir, Deepti Singh, Alyiah Karmali, Saif Somani, Toral R. Patel, Ankur Patel, Kimmo J. Hatanpaa, Michael Youssef, Nawal Shaikh, Carissa Ye, Dawen Zhao, Sandeep Burma, Jann N. Sarkaria, Nazanin K. Majd, Mansoor Saleh, Alain Charest, C. Ryan Miller, Louis B. Nabors, Mary Susmitha Kataru, Chandler E. Tolbert, Fatima Jimenez, Syed Ather Enam, Amyn A. Habib, Gao Guo

Open source

DOI: 10.1126/scitranslmed.adx8398
Published: 2026-07-08
Container: Science Translational Medicine
Publisher: American Association for the Advancement of Science (AAAS)
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1126/scitranslmed.adx8398,
  title = {EGFR inhibition down-regulates MGMT and enhances responsiveness to temozolomide in glioblastoma},
  author = {Arifa Nayab and Nouman Mughal and Meher Angez and Sansi Xing and Aarohan M. Burma and Harshitha Balla and Sani H. Kizilbash and Xiaoyao Yang and Muhammad Asad Maqbool and Fazal Arain and Azhar Hussain and Sahara Amir and Deepti Singh and Alyiah Karmali and Saif Somani and Toral R. Patel and Ankur Patel and Kimmo J. Hatanpaa and Michael Youssef and Nawal Shaikh and Carissa Ye and Dawen Zhao and Sandeep Burma and Jann N. Sarkaria and Nazanin K. Majd and Mansoor Saleh and Alain Charest and C. Ryan Miller and Louis B. Nabors and Mary Susmitha Kataru and Chandler E. Tolbert and Fatima Jimenez and Syed Ather Enam and Amyn A. Habib and Gao Guo},
  year = {2026},
  journal = {Science Translational Medicine},
  doi = {10.1126/scitranslmed.adx8398},
  url = {https://doi.org/10.1126/scitranslmed.adx8398}
}

RIS

TY  - JOUR
TI  - EGFR inhibition down-regulates MGMT and enhances responsiveness to temozolomide in glioblastoma
AU  - Arifa Nayab
AU  - Nouman Mughal
AU  - Meher Angez
AU  - Sansi Xing
AU  - Aarohan M. Burma
AU  - Harshitha Balla
AU  - Sani H. Kizilbash
AU  - Xiaoyao Yang
AU  - Muhammad Asad Maqbool
AU  - Fazal Arain
AU  - Azhar Hussain
AU  - Sahara Amir
AU  - Deepti Singh
AU  - Alyiah Karmali
AU  - Saif Somani
AU  - Toral R. Patel
AU  - Ankur Patel
AU  - Kimmo J. Hatanpaa
AU  - Michael Youssef
AU  - Nawal Shaikh
AU  - Carissa Ye
AU  - Dawen Zhao
AU  - Sandeep Burma
AU  - Jann N. Sarkaria
AU  - Nazanin K. Majd
AU  - Mansoor Saleh
AU  - Alain Charest
AU  - C. Ryan Miller
AU  - Louis B. Nabors
AU  - Mary Susmitha Kataru
AU  - Chandler E. Tolbert
AU  - Fatima Jimenez
AU  - Syed Ather Enam
AU  - Amyn A. Habib
AU  - Gao Guo
PY  - 2026
JO  - Science Translational Medicine
DO  - 10.1126/scitranslmed.adx8398
UR  - https://doi.org/10.1126/scitranslmed.adx8398
ER  -

APA

Nayab, A., Mughal, N., Angez, M., Xing, S., Burma, A. M., Balla, H., Kizilbash, S. H., Yang, X., Maqbool, M. A., Arain, F., Hussain, A., Amir, S., Singh, D., Karmali, A., Somani, S., Patel, T. R., Patel, A., Hatanpaa, K. J., Youssef, M., Shaikh, N., Ye, C., Zhao, D., Burma, S., Sarkaria, J. N., Majd, N. K., Saleh, M., Charest, A., Miller, C. R., Nabors, L. B., Kataru, M. S., Tolbert, C. E., Jimenez, F., Enam, S. A., Habib, A. A., & Guo, G. (2026). EGFR inhibition down-regulates MGMT and enhances responsiveness to temozolomide in glioblastoma. Science Translational Medicine. https://doi.org/10.1126/scitranslmed.adx8398

Source records

crossref · retrieved 2026-09-26T16:44:49.473Z