Extended in vivo activity of VRC01 HIV-1 prophylaxis entails initial protective efficacy and subsequent breakthrough infections

Allan C. deCamp, Michal Juraska, Li Li, Craig A. Magaret, Brian D. Williamson, Hongjun Bai, Yunda Huang, Elena E. Giorgi, Lily Zhang, Lindsay N. Carpp, Srilatha Edupuganti, Nyaradzo M. Mgodi, Kevin Gillespie, Beatrix Haddock, Pedro Gonzales, Robinson Cabello, Catherine Orrell, Javier R. Lama, Fatima Laher, Erica M. Lazarus, Jorge Sanchez, Ian Frank, Juan C. Hinojosa, Magdalena E. Sobieszczyk, Pamela G. Mukwekwerere, Joseph Makhema, Lindsey R. Baden, Kelly E. Seaton, John Hural, M. Juliana McElrath, Simbarashe Takuva, April K. Randhawa, Nidhi Kochar, Estelle Piwowar-Manning, Deborah J. Donnell, Nirupama Sista, Philip Andrew, Shelly T. Karuna, James G. Kublin, Glenda E. Gray, Myron S. Cohen, Dan H. Barouch, Georgia D. Tomaras, Morgane Rolland, David C. Montefiori, Lynn Morris, James I. Mullins, Carolyn Williamson, Lawrence Corey, Peter B. Gilbert

Open source

DOI
10.1126/scitranslmed.aec3480
Published
2026-11-04
Container
Science Translational Medicine
Publisher
American Association for the Advancement of Science (AAAS)
Open access
unknown

Credibility signals

uncertain Score 64/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

Cite this work

BibTeX

@article{allodium:10.1126/scitranslmed.aec3480,
  title = {Extended in vivo activity of VRC01 HIV-1 prophylaxis entails initial protective efficacy and subsequent breakthrough infections},
  author = {Allan C. deCamp and Michal Juraska and Li Li and Craig A. Magaret and Brian D. Williamson and Hongjun Bai and Yunda Huang and Elena E. Giorgi and Lily Zhang and Lindsay N. Carpp and Srilatha Edupuganti and Nyaradzo M. Mgodi and Kevin Gillespie and Beatrix Haddock and Pedro Gonzales and Robinson Cabello and Catherine Orrell and Javier R. Lama and Fatima Laher and Erica M. Lazarus and Jorge Sanchez and Ian Frank and Juan C. Hinojosa and Magdalena E. Sobieszczyk and Pamela G. Mukwekwerere and Joseph Makhema and Lindsey R. Baden and Kelly E. Seaton and John Hural and M. Juliana McElrath and Simbarashe Takuva and April K. Randhawa and Nidhi Kochar and Estelle Piwowar-Manning and Deborah J. Donnell and Nirupama Sista and Philip Andrew and Shelly T. Karuna and James G. Kublin and Glenda E. Gray and Myron S. Cohen and Dan H. Barouch and Georgia D. Tomaras and Morgane Rolland and David C. Montefiori and Lynn Morris and James I. Mullins and Carolyn Williamson and Lawrence Corey and Peter B. Gilbert},
  year = {2026},
  journal = {Science Translational Medicine},
  doi = {10.1126/scitranslmed.aec3480},
  url = {https://doi.org/10.1126/scitranslmed.aec3480}
}

RIS

TY  - JOUR
TI  - Extended in vivo activity of VRC01 HIV-1 prophylaxis entails initial protective efficacy and subsequent breakthrough infections
AU  - Allan C. deCamp
AU  - Michal Juraska
AU  - Li Li
AU  - Craig A. Magaret
AU  - Brian D. Williamson
AU  - Hongjun Bai
AU  - Yunda Huang
AU  - Elena E. Giorgi
AU  - Lily Zhang
AU  - Lindsay N. Carpp
AU  - Srilatha Edupuganti
AU  - Nyaradzo M. Mgodi
AU  - Kevin Gillespie
AU  - Beatrix Haddock
AU  - Pedro Gonzales
AU  - Robinson Cabello
AU  - Catherine Orrell
AU  - Javier R. Lama
AU  - Fatima Laher
AU  - Erica M. Lazarus
AU  - Jorge Sanchez
AU  - Ian Frank
AU  - Juan C. Hinojosa
AU  - Magdalena E. Sobieszczyk
AU  - Pamela G. Mukwekwerere
AU  - Joseph Makhema
AU  - Lindsey R. Baden
AU  - Kelly E. Seaton
AU  - John Hural
AU  - M. Juliana McElrath
AU  - Simbarashe Takuva
AU  - April K. Randhawa
AU  - Nidhi Kochar
AU  - Estelle Piwowar-Manning
AU  - Deborah J. Donnell
AU  - Nirupama Sista
AU  - Philip Andrew
AU  - Shelly T. Karuna
AU  - James G. Kublin
AU  - Glenda E. Gray
AU  - Myron S. Cohen
AU  - Dan H. Barouch
AU  - Georgia D. Tomaras
AU  - Morgane Rolland
AU  - David C. Montefiori
AU  - Lynn Morris
AU  - James I. Mullins
AU  - Carolyn Williamson
AU  - Lawrence Corey
AU  - Peter B. Gilbert
PY  - 2026
JO  - Science Translational Medicine
DO  - 10.1126/scitranslmed.aec3480
UR  - https://doi.org/10.1126/scitranslmed.aec3480
ER  - 

APA

deCamp, A. C., Juraska, M., Li, L., Magaret, C. A., Williamson, B. D., Bai, H., Huang, Y., Giorgi, E. E., Zhang, L., Carpp, L. N., Edupuganti, S., Mgodi, N. M., Gillespie, K., Haddock, B., Gonzales, P., Cabello, R., Orrell, C., Lama, J. R., Laher, F., Lazarus, E. M., Sanchez, J., Frank, I., Hinojosa, J. C., Sobieszczyk, M. E., Mukwekwerere, P. G., Makhema, J., Baden, L. R., Seaton, K. E., Hural, J., McElrath, M. J., Takuva, S., Randhawa, A. K., Kochar, N., Piwowar-Manning, E., Donnell, D. J., Sista, N., Andrew, P., Karuna, S. T., Kublin, J. G., Gray, G. E., Cohen, M. S., Barouch, D. H., Tomaras, G. D., Rolland, M., Montefiori, D. C., Morris, L., Mullins, J. I., Williamson, C., Corey, L., & Gilbert, P. B. (2026). Extended in vivo activity of VRC01 HIV-1 prophylaxis entails initial protective efficacy and subsequent breakthrough infections. Science Translational Medicine. https://doi.org/10.1126/scitranslmed.aec3480

Source records