Cas9 nickase-mediated contraction of CAG/CTG repeats is associated with phenotypic improvements in a Huntington's disease mouse model.

Murillo A, Alpaugh M, Peter Durairaj RR, Randall EL, Larin M, Heraty L, Aston AN, Taylor AS, Monteys AM, Stöberl N, Heuchan AER, Aeschlimann P, Fears K, Landles C, Osborne GF, Mangin A, Bhattacharyya S, Metzakopian E, Allen ND, Puymirat J, Bates GP, Davidson BL, Cicchetti F, Lelos MJ, Dion V

Open source

DOI: 10.1126/scitranslmed.aef9466
Published: 2026 Oct 21
Container: Science translational medicine
Publisher: Not recorded
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.1126/scitranslmed.aef9466,
  title = {Cas9 nickase-mediated contraction of CAG/CTG repeats is associated with phenotypic improvements in a Huntington's disease mouse model.},
  author = {Murillo A and Alpaugh M and Peter Durairaj RR and Randall EL and Larin M and Heraty L and Aston AN and Taylor AS and Monteys AM and Stöberl N and Heuchan AER and Aeschlimann P and Fears K and Landles C and Osborne GF and Mangin A and Bhattacharyya S and Metzakopian E and Allen ND and Puymirat J and Bates GP and Davidson BL and Cicchetti F and Lelos MJ and Dion V},
  year = {2026},
  journal = {Science translational medicine},
  doi = {10.1126/scitranslmed.aef9466},
  url = {https://doi.org/10.1126/scitranslmed.aef9466}
}

RIS

TY  - JOUR
TI  - Cas9 nickase-mediated contraction of CAG/CTG repeats is associated with phenotypic improvements in a Huntington's disease mouse model.
AU  - Murillo A
AU  - Alpaugh M
AU  - Peter Durairaj RR
AU  - Randall EL
AU  - Larin M
AU  - Heraty L
AU  - Aston AN
AU  - Taylor AS
AU  - Monteys AM
AU  - Stöberl N
AU  - Heuchan AER
AU  - Aeschlimann P
AU  - Fears K
AU  - Landles C
AU  - Osborne GF
AU  - Mangin A
AU  - Bhattacharyya S
AU  - Metzakopian E
AU  - Allen ND
AU  - Puymirat J
AU  - Bates GP
AU  - Davidson BL
AU  - Cicchetti F
AU  - Lelos MJ
AU  - Dion V
PY  - 2026
JO  - Science translational medicine
DO  - 10.1126/scitranslmed.aef9466
UR  - https://doi.org/10.1126/scitranslmed.aef9466
ER  -

APA

A, M., M, A., RR, P. D., EL, R., M, L., L, H., AN, A., AS, T., AM, M., N, S., AER, H., P, A., K, F., C, L., GF, O., A, M., S, B., E, M., ND, A., J, P., GP, B., BL, D., F, C., MJ, L., & V, D. (2026). Cas9 nickase-mediated contraction of CAG/CTG repeats is associated with phenotypic improvements in a Huntington's disease mouse model.. Science translational medicine. https://doi.org/10.1126/scitranslmed.aef9466

Source records

pubmed · retrieved 2026-11-10T10:39:21.476Z