A phase 1 feasibility trial of BE-CAR33, an "off-the-shelf" base-edited CAR33 T cell therapy for acute myeloid leukemia.

Georgiadis C, Chiesa R, Rashed H, Hughes BK, Preece R, Gough O, Pinner D, Adams S, Thomas R, Etuk A, Mishra A, Zhan H, Braybrook T, Gilmour K, Potter V, Bartram J, Ancliff P, Sauer M, Qasim W, Base Edited-CAR T cell group, Base-Edited CAR T Group.

Open source

DOI
10.1126/scitranslmed.aei0875
Published
2026-08-19
Container
Sci Transl Med
Publisher
Not recorded
Open access
no

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BibTeX

@article{allodium:10.1126/scitranslmed.aei0875,
  title = {A phase 1 feasibility trial of BE-CAR33, an "off-the-shelf" base-edited CAR33 T cell therapy for acute myeloid leukemia.},
  author = {Georgiadis C and  Chiesa R and  Rashed H and  Hughes BK and  Preece R and  Gough O and  Pinner D and  Adams S and  Thomas R and  Etuk A and  Mishra A and  Zhan H and  Braybrook T and  Gilmour K and  Potter V and  Bartram J and  Ancliff P and  Sauer M and  Qasim W and  Base Edited-CAR T cell group and  Base-Edited CAR T Group.},
  year = {2026},
  journal = {Sci Transl Med},
  doi = {10.1126/scitranslmed.aei0875},
  url = {https://doi.org/10.1126/scitranslmed.aei0875}
}

RIS

TY  - JOUR
TI  - A phase 1 feasibility trial of BE-CAR33, an "off-the-shelf" base-edited CAR33 T cell therapy for acute myeloid leukemia.
AU  - Georgiadis C
AU  -  Chiesa R
AU  -  Rashed H
AU  -  Hughes BK
AU  -  Preece R
AU  -  Gough O
AU  -  Pinner D
AU  -  Adams S
AU  -  Thomas R
AU  -  Etuk A
AU  -  Mishra A
AU  -  Zhan H
AU  -  Braybrook T
AU  -  Gilmour K
AU  -  Potter V
AU  -  Bartram J
AU  -  Ancliff P
AU  -  Sauer M
AU  -  Qasim W
AU  -  Base Edited-CAR T cell group
AU  -  Base-Edited CAR T Group.
PY  - 2026
JO  - Sci Transl Med
DO  - 10.1126/scitranslmed.aei0875
UR  - https://doi.org/10.1126/scitranslmed.aei0875
ER  - 

APA

C, G., R, C., H, R., BK, H., R, P., O, G., D, P., S, A., R, T., A, E., A, M., H, Z., T, B., K, G., V, P., J, B., P, A., M, S., W, Q., group, B. E. T. C., & Group., B. C. T. (2026). A phase 1 feasibility trial of BE-CAR33, an "off-the-shelf" base-edited CAR33 T cell therapy for acute myeloid leukemia.. Sci Transl Med. https://doi.org/10.1126/scitranslmed.aei0875

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